Bone Mineral Density News and Research

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$Ankle fracture severity linked to obesity$

Ankle fracture severity linked to obesity

Obese patients experience more severe ankle fractures than individuals with a healthy body mass index, research suggests.

12 Jul 2012

Merck announces update on odanacatib Phase III trial for osteoporosis

Merck, known as MSD outside the United States and Canada, announced today an update on the Phase III trial assessing fracture risk reduction with odanacatib, Merck's investigational cathepsin K (cat-K) inhibitor.

12 Jul 2012

Mechanical treatment shows promise in thalassemia

Vibration therapy may be an effective nonpharmacologic intervention to increase bone mass in patients with thalassemia, US researchers report

10 Jul 2012

High ferritin warns of bone loss

Individuals with high levels of ferritin, an indicator of iron stores within the body, have accelerated bone loss at the proximal femur, Korean researchers report.

10 Jul 2012

$Vertebral fracture more common among Chinese women than men$

Vertebral fracture more common among Chinese women than men

Vertebral deformities occur at a similar rate among Chinese men and women aged 65 years or older, research findings show.

10 Jul 2012

Platelet activation linked to osteoporosis

Elderly, postmenopausal women with osteoporosis have elevated platelet volumes, report researchers.

2 Jul 2012

$Epilepsy patients unaware of fracture risk$

Epilepsy patients unaware of fracture risk

Few patients with epilepsy are aware that taking anti-epileptic drugs puts them at increased risk for falls and fractures, report researchers.

29 Jun 2012

Young inflammatory bowel disease patients have low bone mass

Children and adolescents with inflammatory bowel disease have significantly lower bone mineral density than their healthy peers, even after adjusting for pubertal delay, Finnish researchers report.

29 Jun 2012

$Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs$

Study sheds light on increased risk of fractures and falls among epilepsy patients using AEDs

New research has shed light on the high risk of fractures, falls, and osteoporosis among epilepsy patients using antiepileptic drugs (AEDs) with most patients unaware of the risks associated with taking the drugs.

29 Jun 2012

Young inflammatory bowel disease patients have low bone mass

Children and adolescents with inflammatory bowel disease have significantly lower bone mineral density than their healthy peers, even after adjusting for pubertal delay, Finnish researchers report.

28 Jun 2012

$Chinese herbal preparation reduces fragility fractures$

Chinese herbal preparation reduces fragility fractures

Herbal Fufang – a multi-herbal preparation used in traditional Chinese medicine –increases bone mineral density and reduces fragility fractures in postmenopausal women, Chinese researchers report.

27 Jun 2012

HIV therapy affects bone mass within 2 years

Young men receiving antiretroviral therapy for recently diagnosed HIV are more likely to have low bone mineral density than are other men of a similar age, US researchers report.

25 Jun 2012

Connexin 43 deficiency may protect against bed rest-associated bone loss

Mice lacking connexin 43, the most abundant gap junction protein in bone, have a decreased susceptibility to the effects of mechanical unloading on bone, US researchers report.

21 Jun 2012

Osteoporosis screening recommended for men at risk

Men at increased risk for osteoporosis should undergo bone mineral density testing with dual energy X-ray absorptiometry, concludes The Endocrine Society’s Clinical Practice Guideline “Osteoporosis in Men.”

20 Jun 2012

IOF review outlines pathophysiology, diagnosis and management of osteoporosis in young adults

Much of the research defining osteoporosis and fracture risk has focused on older adults, i.e. postmenopausal women and men over the age of 50. While older adults are at highest risk of osteoporosis and related fractures, the disease can also affect younger adults between 20 and 50 years of age. However, the diagnosis and management of osteoporosis in young adults is complicated by special challenges, including a complex pathophysiology and the related fact that there is no clear definition of osteoporosis, or of intervention thresholds, in this age group.

20 Jun 2012

Young men with HIV more likely to experience low bone mass

Young men being treated for HIV are more likely to experience low bone mass than are other men their age, according to results from a research network supported by the National Institutes of Health. The findings indicate that physicians who care for these patients should monitor them regularly for signs of bone thinning, which could foretell a risk for fractures. The young men in the study did not have HIV at birth and had been diagnosed with HIV an average of two years earlier.

20 Jun 2012

Clinical practice guidelines for management of osteoporosis in men

Osteoporosis in men causes significant morbidity and mortality. Today, the Endocrine Society released clinical practice guidelines (CPG) for management of this condition in men.

19 Jun 2012

Osteoporosis self-reports unreliable measure for case defintions

Self-reports of incident osteoporosis in middle-aged and older women should not be relied on for a case definition, suggest study findings showing poor-to-moderate validity for this measure.

14 Jun 2012

$Environmental factors more important than genetic for vertebral fracture$

Environmental factors more important than genetic for vertebral fracture

Individual-specific environmental factors such as lifestyle have a greater influence on vertebral fracture risk than genetic factors, suggest study findings.

13 Jun 2012

Genetic influence on postmenopausal bone loss falls with age

The effect of genetics on bone loss rates in postmenopausal women reduces until the age of 65 years, after which time its influence disappears completely, according to results from a twin-based study.

8 Jun 2012