Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Harmful alcohol consumption pattern may damage heart tissue

A pattern of harmful alcohol consumption, or heavy drinking, increases level of blood biomarkers indicating heart tissue damage, according to new research published today in the Journal of the American Heart Association, the open access journal of the American Heart Association.

18 Dec 2019

Genetic variant mainly found in individuals of African ancestry increases odds of heart failure

A genetic variant in the gene transthyretin (TTR)- which is found in about 3 percent of individuals of African ancestry- is a more significant cause of heart failure than previously believed, according to a multi-institution study led by researchers at Penn Medicine.

10 Dec 2019

Study identifies genetic variation linked to heart failure risk in people of African, Latino ancestry

A genetic variation believed to increase risk for heart failure in people of African or Latino ancestry has been identified in a new study by researchers from the Icahn School of Medicine at Mount Sinai and Perelman School of Medicine at the University of Pennsylvania.

9 Dec 2019

New program receives national recognition for treating hypertrophic cardiomyopathy

When Kayla Green was first diagnosed with hypertrophic cardiomyopathy, she felt vindicated.

4 Dec 2019

Study finds increase in pediatric palliative care involvement for children with VADs

At the study hospital, pediatric palliative care (PPC) involvement for children with VADs has sharply increased in recent years, according to the new research by Christopher Knoll, MD, and colleagues of Lucile Packard Children's Hospital Stanford, Palo Alto, Calif.

27 Nov 2019

Early diagnosis of peripartum cardiomyopathy associated with improved outcomes

Women who are diagnosed with peripartum cardiomyopathy (PPCM) during late pregnancy or within a month following delivery are more likely to experience restored cardiac function and improved outcomes compared to those who are diagnosed later in the postpartum period, according to a new study from Penn Medicine.

17 Nov 2019

Pacemaker-like device improves heart function in patients with chemotherapy-induced cardiomyopathy

With the advent of new therapies, cancer patients are surviving longer than ever before -- but the incidence of side-effect chemotherapy-induced cardiomyopathy (CHIC), or weakness of the heart muscle, is increasing.

13 Nov 2019

Cardiac resynchronization therapy improves heart function in cancer survivors

A pacemaker-like device restored heart function in a group of cancer survivors -- mostly women with breast cancer -- who had suffered from heart failure as a result of chemotherapy treatment, a study in the Journal of the American Medical Association reports.

12 Nov 2019

Researchers reveal initial results from a study of hypertrophic cardiomyopathy

Researchers have revealed the initial results from the world's largest comprehensive study of hypertrophic cardiomyopathy, an abnormal thickening of the heart that often goes undiagnosed and can prove deadly. The condition can present at any age, and it is the most common cause of sudden cardiac death in young athletes.

7 Nov 2019

Study identifies a kinase as potential target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies.

31 Oct 2019

Decision support tool could avert needless referrals of low-risk patients to cardiac specialists

Few events strike more fear in parents than hearing their child's heart "hurts."

25 Oct 2019

Cleveland Clinic announces Top 10 Medical Innovations for 2020

A dual-acting osteoporosis drug. Minimally invasive mitral valve surgery. New treatment for peanut allergies. These are some of the innovations that will enhance healing and change healthcare in the coming year, according to a distinguished panel of doctors and researchers.

23 Oct 2019

Signaling defects could cause congenital heart condition

A congenital heart condition known as left ventricular non-compaction (LVNC) - which occurs when muscly projections in the embryonic heart fail to transform into compact heart muscle - could be caused by signaling defects, according to new preclinical research led by Duke-NUS Medical School in Singapore.

17 Oct 2019

New drug treats inflammation related to inherited heart disease in young athletes

When young athletes experiences sudden cardiac death as they run down the playing field, it's usually due to arrhythmogenic cardiomyopathy, an inherited heart disease.

From Johns Hopkins Medicine 17 Oct 2019

Study reveals new and surprising function of adenine nucleotide translocator

Mutations in the gene that encodes a protein called adenine nucleotide translocator (ANT) cause a variety of conditions, such as heart disease and weakness of the eye muscles, but the underlying mechanism of how these mutations trigger disease has been unclear.

16 Oct 2019

β-blockers could regenerate infant heart muscle, mitigate effects of congenital heart disease

Surgery can mend congenital heart defects shortly after birth, but those babies will carry a higher risk of heart failure throughout the rest of their lives. Yet, according to a Science Translational Medicine study published today by UPMC Children's Hospital of Pittsburgh researchers, β-blockers could supplement surgery to regenerate infant heart muscle and mitigate the lasting effects of congenital heart disease.

9 Oct 2019

New drug Aliskiren shows promise for heart failure patients

A study published in the International Journal of Molecular Sciences, as part of a special issue “Heart Failure: From Molecular Basis to Therapy”, in August 2019, shows that aliskiren, a drug approved by the US Food and Drug Administration (FDA), can improve survival for over 5 years, on average, and enhance life quality in patients who have been correctly diagnosed with heart failure.

9 Oct 2019

Aliskiren drug can delay progression of congestive heart failure, lengthen survival rates

Researchers at the University of Arizona College of Medicine - Phoenix have shown for the first time in preclinical studies that Aliskiren, a drug that inhibits the enzyme that regulates blood pressure, can delay the progression of congestive heart failure and lengthen survival rates.

8 Oct 2019

Research findings open the way for more heart donations

There is a risk of every fourth heart examined for possible donation being dismissed as unusable due to stress-induced heart failure.

26 Sep 2019

Study finds no overall improvement in heart transplant waitlist after policy change

In March 2016, the Organ Procurement and Transplantation Network revised its criteria for prioritizing children awaiting heart transplantation in the U.S. with the intention of reducing the number of deaths on the waitlist, but a new study suggests unintended consequences.

23 Sep 2019