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One type of Chlamydia protein manipulates human cells in two different ways

When Chlamydia trachomatis, the bacterium that causes one of the most common sexually transmitted infections worldwide, infects a human cell, it hijacks parts of the host to build protective layers around itself.

8 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

Texas A&M study identifies new brain region involved in inhibiting fear

A study conducted at Texas A&M University has identified a new area in the brain involved in inhibiting fear, a discovery that holds potential for clinical interventions in patients with psychiatric diseases such as post-traumatic stress disorder.

31 Oct 2018

Top researchers call for unified standards in 3D genome and epigenetic data

Studying the three-dimensional structure of DNA and its dynamics is revealing a lot of information about gene expression, expanding our knowledge of how cells, tissues and organs actually work in health and disease.

30 Oct 2018

Dopamine neurons play role in reinforcing addictive effects of heroin

Scientists have made a major advance in untangling the brain circuits that lead to the powerful addictive effects of heroin, a study in the open-access journal eLife reports.

30 Oct 2018

Ten Allen Distinguished Investigators for 2018 announced by Paul G. Allen Frontiers Group

Nanoparticles that could reprogram a cancer patient's immune system inside their own body. Understanding a mysterious type of brain cell in the hopes of shedding new light on Alzheimer's disease. Reimagining nuclei, the DNA-storage compartments of our cells, as miniature lava lamps.

30 Oct 2018

Physician-scientists treat first patient in the U.S. with focused ultrasound for neuropathic leg pain

University of Maryland physician-scientists have treated the first patient in the United States with MRI-guided focused ultrasound for neuropathic leg pain as part of a pilot clinical trial.

30 Oct 2018

Quantum dot-based FISH method enhances cell imaging

A team of researchers from the University of Illinois at Urbana-Champaign and Mayo Clinic have engineered a new type of molecular probe that can measure and count RNA in cells and tissue without organic dyes.

30 Oct 2018

Duke researchers find way to detect blood doping in athletes

A Duke University research team has found a way to help sporting officials detect whether an athlete's blood has been doped by an infusion of their own stored blood.

19 Oct 2018

Gene sequencing reveals crucial molecular aspects of Trypanosoma brucei

Trypanosoma brucei, which causes sleeping sickness, evades the immune system by repeatedly altering the structure of its surface coat. Sequencing of its genome and studies of its 3D genome architecture have now revealed crucial molecular aspects of this strategy.

19 Oct 2018

Findings offer new insight into early changes that occur during AD pathology

Alzheimer's disease (AD) is the most common form of dementia, involving memory loss and a reduction in cognitive abilities.

12 Oct 2018

Scientists use haploid stem cells to produce mice with same-sex parents

In a new study, Chinese researchers were able to produce healthy mouse pups with two mothers. The research involved the use of haploid embryonic stem cells.

12 Oct 2018

Thalamus controls development of normal sleep and waking states, study finds

Consciousness requires continuous, internally generated activity in the brain. The modulation of this activity is the basis of the electroencephalogram (EEG) and of generation of sleep, dreams, and perception.

12 Oct 2018

Greater family size reduces cancer risk

Families with many children have a lower risk of cancer. Greater family size reduces the risk not only in women but also in men, a global study using data from 178 countries by the University of Zurich and the Adelaide Medical School has found.

10 Oct 2018

Massively parallel single-nucleus RNA sequencing reveals insights into heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

9 Oct 2018

Researchers identify neurons essential for normal sleep

Two decades ago, Clifford B. Saper, MD/PhD, Chairman of the Department of Neurology at Beth Israel Deaconess Medical Center, and colleagues discovered a set of nerve cells they thought might be the switch that turns the brain off, allowing it to sleep.

8 Oct 2018

New method for studying the cell nucleus could improve disease detection

Researchers at New York University have found a way to measure the physical properties of the nucleus and its constituents in live human cells.

5 Oct 2018

RNA sequencing method uncovers new insights into biological events in heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

5 Oct 2018

Researchers develop molecule that makes cancer cells sensitive to radiotherapy

Researchers from Karolinska Institutet and Kancera AB have developed a molecule that makes cancer cells sensitive to radiotherapy. In a study published in Nature Communications, the researchers describe a new way to block cancer cells' ability to repair their DNA and thus stop the survival of cancer cells.

25 Sep 2018