Clostridium News and Research

RSS

Salmonella cases are not associated with Danish broiler meat, shows report

The number of Danes who contracted a salmonella infection reached a historic low level in 2013. More than half of those infected became ill during a trip abroad.

20 Jun 2014

Fecal microbiota transplantation works by restoring healthy bacteria and functioning to recipient's gut

Fecal microbiota transplantation --- the process of delivering stool bacteria from a healthy donor to a patient suffering from intestinal infection with the bacterium Clostridium difficile --- works by restoring healthy bacteria and functioning to the recipient's gut, according to a study published this week in mBio-, the online open-access journal of the American Society for Microbiology.

17 Jun 2014

C. difficile bacteria pose major health threat without proper infection prevention in hospitals, homes

Without proper infection prevention in hospitals, and now homes, the Clostridium difficile bacteria poses a major health threat, cautions a Case Western Reserve University infection control researcher.

17 Jun 2014

Specific enzyme helps protect good commensal bacteria from harmful effects of antibiotics

Researchers from Case Western Reserve University in Cleveland have discovered that populating the gastrointestinal (GI) tracts of mice with Bacteroides species producing a specific enzyme helps protect the good commensal bacteria from the harmful effects of antibiotics.

13 Jun 2014

Superbugs decrease among patients after adding UVD to cleaning regimen

Healthcare-associated vancomycin-resistant enterococcus (VRE), methicillin-resistant Staphylococcus aureus (MRSA), Clostridium difficile (CD), and other multidrug-resistant organisms (MDRO) were decreased among patients after adding ultraviolet environmental disinfection (UVD) to the cleaning regimen, according to a study published in the June issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

28 May 2014

Sanofi presents Phase II trial results for investigational vaccine for prevention of CDI

Sanofi Pasteur, the vaccines division of Sanofi, presented Phase II (H-030-012) trial results for an investigational vaccine for the prevention of Clostridium difficile infection at the 114th General Meeting of the American Society for Microbiology.

20 May 2014

Auxilium Pharmaceuticals presents new XIAFLEX clinical trial data at AUA Meeting

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced that new analyses of data were presented from its clinical program and pivotal IMPRESS (The Investigation for Maximal Peyronie's Reduction Efficacy and Safety Studies) trials, the Phase 3 studies that evaluated XIAFLEX® (collagenase clostridium histolyticum or CCH) for the treatment of Peyronie's disease (PD).

19 May 2014

Da Volterra presents promising results of DAV-132 compound for prevention of severe C. diff infections

Da Volterra, a leading biopharmaceutical company in the field of bacterial resistance, announces today very promising new results about DAV132 in the prevention of the side effects of antibiotics and the occurrence of severe Clostridium difficile infections.

13 May 2014

Luminex announces group B strep as fifth assay planned for launch menu of ARIES

Luminex Corporation today announced that Group B Streptococcus (group B strep, GBS) is the fifth assay planned for the launch menu of its new sample-to-answer system, ARIES™.

From Luminex 12 May 2014

New expert guidance encourages healthcare institutions to implement prevention efforts infectious diarrhea

With rates of Clostridium difficile (C. difficile) now rivaling drug-resistant Methicillin-resistant Staphylococcus aureus (MRSA) as the most common bacteria to cause healthcare-associated infections, new expert guidance encourages healthcare institutions to implement and prioritize prevention efforts for this infectious diarrhea.

7 May 2014

Use of frozen stool for fecal transplant successfully treats C. difficile infection

Using frozen stool from healthy, unrelated donors was safe and effective in treating patients with serious, relapsing diarrhea caused by Clostridium difficile, according to a new pilot study published in Clinical Infectious Diseases and available online.

25 Apr 2014

Nearly 179 million cases of acute diarrhea occur each year in the U.S.

In the United States, approximately 179 million cases of acute diarrhea occur each year, and most of those cases are entirely preventable, a researcher from The University of Texas Health Science Center at Houston concluded in a New England Journal of Medicine review article.

23 Apr 2014

Freiburg researchers discover molecule that smuggles toxins from intestinal pathogens into human cells

Prof. Dr. Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the Institute of Experimental and Clinical Pharmacology and Toxicology of the University of Freiburg have discovered the receptor responsible for smuggling the toxin of the bacterium Clostridium perfringens into the cell.

17 Apr 2014

Daylight Medical releases SKY 6Xi disinfection technology for mobile devices

Daylight Medical, manufacturer and provider of innovative medical products, is pleased to announce its rollout of SKY 6Xi, disinfection technology for mobile devices. SKY 6Xi uses high intensity (254 nanometer wavelength) ultraviolet light in the "C" spectrum (UVC) at close proximity to thoroughly disinfect a mobile device. The unique power of SKY reduces the risk that Hospital-acquired infections (HAIs) are transmitted to patients while improving safety for healthcare workers.

15 Apr 2014

New data shows that gut microbiota has potential role in development of ALD

Exciting new data presented today at the International Liver Congress- 2014 shows that the gut microbiota has a potential role in the development of alcoholic liver disease (ALD).

15 Apr 2014

Expert guidance highlights strategies to prevent catheter-associated urinary tract infections

New expert guidance highlights strategies for implementing and prioritizing efforts to prevent catheter-associated urinary tract infections (CAUTI) in hospitals.

9 Apr 2014

Hospital infection rates down, but patients still dying of preventable causes

Hospitals and nursing homes have been trying to cut the facility-acquired infection rates, which has worked better for some conditions than others.

28 Mar 2014

PCORI to award $7 million contract to Chicago coalition to establish clinical data research network

On December 17, 2013, the Patient-Centered Outcomes Research Institute (PCORI) announced its intention to award an 18-month, $7 million contract to a Chicago area coalition of 20 health and hospital organizations including Loyola University Health System.

12 Mar 2014

Study: Severe C. difficile infections occur among children who prescribed antibiotics in doctor's offices

The majority of pediatric Clostridium difficile infections, which are bacterial infections that cause severe diarrhea and are potentially life-threatening, occur among children in the general community who recently took antibiotics prescribed in doctor's offices for other conditions, according to a new study by the Centers for Disease Control and Prevention published this week in Pediatrics.

10 Mar 2014

Viewpoints: Obama's budget punts on entitlements; Medicaid debate rankles states

There is a lesson in this unexpected juxtaposition nevertheless: No nation can safely base its tax and spending plans on inflexible commitments. Political life, both domestic and international, is too unpredictable. Yet U.S. government spending is mostly on autopilot. The government is scheduled to lay out $3.8 trillion this fiscal year - 70 percent of which will go to mandatory-spending programs, chiefly Social Security, Medicare, Medicaid and interest on the federal debt. Mr. Obama's plan for fiscal 2015 does not change this; it would increase overall spending slightly, paying for it with selected tax increases, while shifting money among priorities here and there. But these tweaks would take place within the same 30 percent of discretionary spending that the current budget contains (3/4).

6 Mar 2014