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Cancer patients receiving anti-PD-1 therapies may experience delayed skin reactions

Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay – sometimes even after treatment has concluded.

19 Jul 2018

Aspirin desensitization can help alleviate alcohol-induced allergies in patients with AERD

Patients who suffer from Aspirin Exacerbated Respiratory Disease often experience an additional allergic reaction when drinking alcohol, including nasal congestion, wheezing, and a runny nose.

10 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Geography may be destiny in end-of-life care for cancer patients

When it comes to how much end-of-life care a patient with cancer receives, geography may, indeed, be destiny, according to new research led by Harvard Medical School that found striking differences in terminal care across different parts of the country.

10 Jul 2018

Targeting multiple proteins may be key to treat neurodegenerative disorders

Nearly all major neurodegenerative diseases - from Alzheimer's to Parkinson's - are defined and diagnosed by the presence of one of four proteins that have gone rogue: tau, amyloid-beta, alpha-synuclein, or TDP-43.

6 Jul 2018

Brain stimulation can reduce a person's intention to commit violent act

Stimulating the prefrontal cortex, the part of the brain responsible for controlling complex ideas and behaviors, can reduce a person's intention to commit a violent act by more than 50 percent, according to research published in the Journal of Neuroscience from the University of Pennsylvania and Nanyang Technological University.

2 Jul 2018

Atlantic Health System starts enrolling patients in four pancreatic cancer clinical trials

Atlantic Health System is now enrolling patients in four pancreatic cancer clinical trials. Angela Alistar, MD, a nationally known expert on pancreatic cancer, is serving as national Principal Investigator on the first trial and as local PI on three other trials.

30 Jun 2018

Penn cancer researchers reveal secrets of 'hot' and 'cold' pancreatic tumors

So-called "hot" tumors filled with T cells are often considered to be more sensitive to immunotherapy compared to "cold" tumors with fewer T cells, but a clear demonstration of why has eluded cancer biologists--until now.

29 Jun 2018

Targeting proteins in semen could prevent sexually transmitted spread of Ebola virus

Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Researchers from the Perelman School of Medicine at the University of Pennsylvania report these findings in a study published this week in the Proceedings of the National Academy of Sciences.

26 Jun 2018

Blocking viral-host interaction slows down flu virus replication, study shows

Influenza A (flu A) hijacks host proteins for viral RNA splicing and blocking these interactions caused replication of the virus to slow, according to new research published in Nature Communications by Kristin W. Lynch, PhD, chair of the department of Biochemistry and Biophysics in the Perelman School of Medicine at the University of Pennsylvania, and doctoral student Matthew Thompson.

25 Jun 2018

UC San Diego launches new bacteriophage therapy center

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America's first Center for Innovative Phage Applications and Therapeutics

22 Jun 2018

'Antifreeze' molecules may hold key to better treatments for brain injuries

The key to better treatments for brain injuries and disease may lie in the molecules charged with preventing the clumping of specific proteins associated with cognitive decline and other neurological problems, researchers from the Perelman School of Medicine at the University of Pennsylvania report in a new study published in Neurobiology of Disease.

22 Jun 2018

Researchers highlight new nurse training model to address shortage of primary care

Nurse practitioners are providing an increasing proportion of primary care, which is in short supply in many areas of the country. NPs deliver quality care in retail clinics, community health centers, rural clinics, and in primary care and specialty medical practices.

21 Jun 2018

Penn Medicine team launches universal stroke awareness program

In an effort to improve stroke recognition and reduce life-threatening pre-hospital delays worldwide, an international team lead by researchers at Penn Medicine created a universal stroke awareness program, Stroke 112.

21 Jun 2018

Combining financial incentives and goal-setting with wearables may encourage heart patients to exercise

Combining financial incentives and personalized goal-setting with wearable devices may be an effective way of encouraging patients with heart disease to increase their physical activity.

13 Jun 2018

Penn research team identifies novel therapeutic target for heart disease

Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure, found researchers from the Perelman School of Medicine at the University of Pennsylvania.

12 Jun 2018

Study finds high insurance denial rates for life-saving hepatitis C drugs in the U.S.

The number of insurance denials for life-saving hepatitis C drugs among patients with both private and public insurers remains high across the United States, researchers from the Perelman School of Medicine at the University of Pennsylvania reported in a new study published in the journal Open Forum Infectious Diseases.

7 Jun 2018

Two-drug combination provides more reliable, effective care for women suffering miscarriage

A combination of the drugs mifepristone and misoprostol can help bring closure to some women and their families suffering from miscarriage, and reduces the need for surgical intervention to complete the painful miscarriage process.

7 Jun 2018

Study: 25% of Americans experience acute insomnia every year

About 25 percent of Americans experience acute insomnia each year, but about 75 percent of these individuals recover without developing persistent poor sleep or chronic insomnia, according to a study from researchers at the Perelman School of Medicine at the University of Pennsylvania which will be presented Monday at SLEEP 2018, the 32nd Annual Meeting of the Associated Professional Sleep Societies LLC.

6 Jun 2018

Medicare financial outlook worsens

Medicare's financial condition has taken a turn for the worse following higher-than-expected hospital spending and reduced payroll taxes that fund the program, the federal government reported Tuesday.

5 Jun 2018

Hospice News and Research

Cancer patients receiving anti-PD-1 therapies may experience delayed skin reactions

Aspirin desensitization can help alleviate alcohol-induced allergies in patients with AERD

Researchers use genome editing to reduce cholesterol levels in animal model

Geography may be destiny in end-of-life care for cancer patients

Targeting multiple proteins may be key to treat neurodegenerative disorders

Brain stimulation can reduce a person's intention to commit violent act

Atlantic Health System starts enrolling patients in four pancreatic cancer clinical trials

Penn cancer researchers reveal secrets of 'hot' and 'cold' pancreatic tumors

Targeting proteins in semen could prevent sexually transmitted spread of Ebola virus

Blocking viral-host interaction slows down flu virus replication, study shows

UC San Diego launches new bacteriophage therapy center

'Antifreeze' molecules may hold key to better treatments for brain injuries

Researchers highlight new nurse training model to address shortage of primary care

Penn Medicine team launches universal stroke awareness program

Combining financial incentives and goal-setting with wearables may encourage heart patients to exercise

Penn research team identifies novel therapeutic target for heart disease

Study finds high insurance denial rates for life-saving hepatitis C drugs in the U.S.

Two-drug combination provides more reliable, effective care for women suffering miscarriage

Study: 25% of Americans experience acute insomnia every year

Medicare financial outlook worsens

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