Induced Pluripotent Stem Cells News and Research

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'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

Age-related macular degeneration is one of the most common causes of vision loss in people over age 65.

10 May 2019

Scientists successfully create melanocyte precursor cells using stem cell technology

Our hair, skin and eyes are colored by a pigment called melanin, which is produced by pigment cells called melanocytes. Scientists have used stem cell technology to successfully create melanocyte precursor cells.

10 May 2019

Human iPSCs make more tiny 'cargo packets' to deliver cellular aging therapies

Johns Hopkins scientists report that adult cells reprogrammed to become primitive stem cells, called induced pluripotent stem cells, make tiny "cargo packets" able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells.

From Johns Hopkins Medicine 8 May 2019

Scientists describe how cells 'decide' between pluripotency and differentiation

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.

3 May 2019

Genetic mutations in brain development lead to discovery of rare genetic diseases

Mutations in a gene involved in brain development have led to the discovery of two new neurodevelopmental diseases by an international team led by researchers at McGill University and CHU Sainte-Justine Research Center.

26 Apr 2019

Combining biomaterial scaffolds with stem cells for tissue engineering applications

StemJournal, a new open access, peer-reviewed journal published by IOS Press, announces publication of its inaugural article, "Combining Stem Cells and Biomaterial Scaffolds for Constructing Tissues and Cell Delivery," by Stephanie M. Willerth, PhD, and Shelly E. Sakiyama-Elbert, PhD.

25 Apr 2019

Researchers create a working model of cerebral tract to study brain function

It takes a lot of connections to create human intelligence. Brain function depends on contacts between multiple regions within the brain.

19 Apr 2019

Two new epigenetic regulators maintain self-renewal of embryonic stem cells

Embryonic stem cells have the ability to self-renew, and, being pluripotent have the potential to create almost any cell type in the body.

19 Apr 2019

New catalog of DNA mutation 'fingerprints' could help doctors pinpoint cancer culprits

Scientists in Cambridge and London have developed a catalog of DNA mutation 'fingerprints' that could help doctors pinpoint the environmental culprit responsible for a patient's tumor - including showing some of the fingerprints left in lung tumors by specific chemicals found in tobacco smoke.

16 Apr 2019

Scientists investigate processes that lead to neuronal death in ALS patients

Amyotrophic lateral sclerosis is an incurable disease of the central nervous system. In most cases, ALS is fatal within a short period following diagnosis.

15 Apr 2019

Human iPSCs-derived mesenchymal stem cells could avoid ageing-related shortfalls

The use of primary mesenchymal stem cells is fraught with ageing-related shortfalls such as limited expansion and early senescence.

11 Apr 2019

UC San Diego Health treats first cancer patient with iPSC-derived cell therapy

After 10 years in remission, Derek Ruff's cancer returned, this time as stage IV colon cancer. Despite aggressive rounds of chemotherapy, palliative radiotherapy and immunotherapy, his disease progressed.

2 Apr 2019

Researchers develop new technology to mass produce cerebral cortex neurons

Korea Brain Research Institute (KBRI, President Pann Ghill Suh) announced on Mar. 4 that its research team led by principal researcher Yoichi Kosodo developed a technology to mass produce cerebral cortex neurons utilizing Induced pluripotent Stem Cells.

28 Mar 2019

Scientific Symposium at LABVOLUTION focuses on key issues in life sciences

The Scientific Symposium at LABVOLUTION will be focusing on key issues in the life sciences. Accordingly, a high level of visitor demand is anticipated.

From LABVOLUTION 25 Mar 2019

Antidepressant drugs may not work when neurons are out of shape

elective serotonin reuptake inhibitors are the most commonly prescribed medication for major depressive disorder, yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.

22 Mar 2019

Major success achieved by Axol Bioscience may help design new brain models

Axol Bioscience, a partner in the EU-funded MESO-BRAIN project (GA # 713140) has had a new proposal selected for funding by the EU through the FET (Future Emerging Technologies) Launchpad scheme.

From Axol Bioscience Ltd 21 Mar 2019

MIT announces creation of the Alana Down Syndrome Center

As part of MIT's continued mission to help build a better world, the Institute announced the creation of the Alana Down Syndrome Center, an innovative new research endeavor, technology development initiative, and fellowship program launched with a $28.6 million gift from Alana Foundation, a nonprofit organization started by Ana Lucia Villela of São Paulo, Brazil.

21 Mar 2019

Researchers find potential therapeutic strategy to treat Alzheimer's

Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro) have identified a potential therapeutic strategy to treat Alzheimer's, according to a study published in Journal of Neuroscience.

20 Feb 2019

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

Increased activity of EHMT2 gene deficient neurons could cause autism in humans

A novel investigation into the impacts of neuronal mutations on autism-related characteristics in humans has been described in the open-access journal eLife.

13 Feb 2019