Progenitor Cells News and Research

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Reduced scar formation in the central nervous system

Neural stem and progenitor cells, from the so-called subventricular zone, can help to repair a brain damaged by central nervous system disorders.

3 Feb 2020

Scientists describe genetic program behind primordial lung progenitors

For the first time, researchers describe the genetic program behind primordial lung progenitors--embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth.

31 Jan 2020

Increased brain growth, mutations and autism linked in new study

Salk Institute researchers have now found a pattern of DNA damage that is unique to brain cells derived from individuals with a single form of autism spectrum disorder (ASD) called macrocephalic ASD. The study, published in the journal Cell Stem Cell in January 2020, may offer an explanation about the developmental misstep that caused this disease.

30 Jan 2020

A single number aids biomedical data scientists in finding deadly cancer cells

Biomedical data scientists at the Stanford University School of Medicine have shown that the number of genes a cell uses to make RNA is a reliable indicator of how developed the cell is, a finding that could make it easier to target cancer-causing genes.

24 Jan 2020

Genes determining the browning of white fat finds study

The fat cells of the body play an essential role in the storage of energy and its release when necessary. Research has shown that apart from energy storage, these adipocytes or fat cells also play a role in hormonal balance and metabolism-regulating hunger. A new study titled, “Systems-genetics-based inference of a core regulatory network underlying white fat browning”, was published in the latest issue of the journal Cell Report.

13 Jan 2020

A molecular switch for repairing damage in central nervous system disorders discovered

A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis, Mayo Clinic researchers discovered.

11 Jan 2020

Mohamad Khazaei receives SCTM’s Young Investigator Award

Mohamad Khazaei, Ph.D., scientific associate in Dr. Michael Fehlings' lab at Krembil Research Institute, Toronto, is the latest recipient of STEM CELLS Translational Medicine's (SCTM) Young Investigator Award.

9 Jan 2020

Scientists explain how a common virus causes havoc on bone marrow, organ transplant patients

For the first time, scientists have discovered the molecular mechanism behind how a common virus can wreak havoc on bone marrow and organ transplant patients, according to a paper published in the journal Cell & Host Microbe.

19 Dec 2019

Modified stroke drug boosts injury repair in rats with spinal cord damage

Adding a modified stroke drug to stem cells used to treat rats with spinal injury boosted the therapy and motor activity.

17 Dec 2019

Stroke drug improves stem cell therapy in rat spinal cord injury models

Four months after treating them, Yasuhiro Shiga, MD, PhD, checked on his rats. Walking into the lab, he carried minimal expectations.

17 Dec 2019

Houston professor uses stem cells to develop next-generation biologic pacemakers

University of Houston associate professor of pharmacology Bradley McConnell is helping usher in a new age of cardiac pacemakers by using stem cells found in fat, converting them to heart cells, and reprogramming those to act as biologic pacemaker cells.

17 Dec 2019

Future cardiac outcomes can be predicted by cellular repair response to exercise

Future cardiac outcomes can be predicted by signs of cardiac stress that appear in the blood in response to exercise, Emory cardiologists report.

4 Dec 2019

Novel remote-controlled 'smart' platform aids in treatment of cardiovascular disease

According to the World Health Organization, cardiovascular disease has become the leading cause of death worldwide. However, vascular regeneration is a promising treatment for cardiovascular disease. Remodeling the endothelium - i.e., forming a confluent vascular endothelial cell monolayer on the lumen - plays a vital role in this process.

3 Dec 2019

Stem cells do help restore heart function – but in a different way

A new study published in the journal Nature shows that stem cells do work well to repair the damaged heart – but in an entirely different manner than was originally supposed. The study shows that stem cells, whether living or dead, when injected into the area of damage in the heart in mice, activate an intense acute inflammation. This triggers the classic wound healing response which finally results in the partial or complete recovery of mechanical function of the injured area.

28 Nov 2019

Researchers discover cellular origins of pediatric brain tumors

A research team led by Dr. Claudia Kleinman, an investigator at the Lady Davis Institute at the Jewish General Hospital, together with Dr. Nada Jabado, of the Research Institute of the McGill University Health Centre, and Dr. Michael Taylor, of The Hospital for Sick Children, discovered that several types of highly aggressive and, ultimately, fatal pediatric brain tumors originate during brain development.

25 Nov 2019

Scientists discover new approach to treating incurable leukemia in children

Acute lymphoblastic leukemia (ALL) is a form of blood cancer that primarily affects children and young people.

25 Nov 2019

Scientists grow complex organoids in the lab

Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.

19 Nov 2019

UCI researchers develop new cell therapy to improve memory, prevent seizures after TBI

Researchers from the University of California, Irvine developed a breakthrough cell therapy to improve memory and prevent seizures in mice following traumatic brain injury.

15 Nov 2019

Lithium corrects radiation damage to brain in young cancer patients

A new study on mice, published online in the journal Molecular Psychiatry, on November 14, 2019, shows that the intermittent use of lithium, which is widely used to stabilize the mood in conditions such as bipolar disorder, can correct memory and learning losses due to radiation therapy to the brain in very young animals, even when the lithium is given long after the injury.

14 Nov 2019

Study: Regular exercise reduces cholesterol, protects the cardiovascular system

Regular exercise protects the cardiovascular system by reducing risk factors such as cholesterol and blood pressure. "But we believe there are certain risk factors for cardiovascular disease that are not fully understood," says Matthias Nahrendorf, MD, PhD, of the Center for Systems Biology at MGH.

7 Nov 2019