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Placental inflammation's role in adult depression and heart disease

An expression signature related to inflammation expressed in Hofbauer cells in the placenta, calculating polygenic risk scores to predict its expression.

14 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

A prospective path for allogeneic cellular immunotherapies.

13 Nov 2023

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

The role of interleukin (IL)-6 and IL-1α in sterile intraamniotic inflammation (SIAI), a condition associated with preterm birth (PTB).

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Concurrent sequencing of DNA and RNA to detect the predisposition to hereditary cancer.

8 Nov 2023

Immune imprinting: The crux of waning COVID-19 booster effectiveness against new variants

The study in Nature Microbiology reviews the concept of immune imprinting and its influence on antibody responses to SARS-CoV-2, highlighting challenges for COVID-19 booster vaccination efficacy against emerging variants. Researchers suggest that understanding immune imprinting is crucial for developing vaccines that elicit broad and lasting immune protection.

7 Nov 2023

The association between neighborhood deprivation, DNA methylation, and gene expression in breast tissue for Black and White women with breast cancer

Researchers investigated the association between neighborhood deprivation and alterations in DNA methylation and gene expression in breast cancer tissues of Black and White women.

7 Nov 2023

TIMP2 protein identified as key player in brain plasticity and memory

Researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix (ECM) of the adult brain hippocampus.

6 Nov 2023

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Researchers have mapped the complex epigenetic and transcriptomic landscape of cancer, revealing key regulatory elements across 11 tumor types that could unlock new insights into cancer progression and metastasis.

5 Nov 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

The Genomic Pre-trained Network (GPN), a multispecies model developed to learn genome-wide variant effects.

31 Oct 2023

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

The efficacy of the bivalent Pfizer-BioNTech COVID-19 messenger ribonucleic acid (mRNA) vaccine BNT162b2 BA.4/5.

30 Oct 2023

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Researchers found that SARS-CoV-2 antigens can persist in the body for up to 14 months after initial infection, challenging the idea that COVID-19 is a transient illness. This finding has implications for understanding long-term effects of the virus and could influence future treatments and vaccines.

30 Oct 2023

What's really in your kombucha and kefir?

Researchers have delved into the bacterial diversity of 47 different fermented foods, revealing significant variations in microbial richness and composition. The study highlights that foods like kombucha and kefirs have high microbial diversity, while plant-based yogurt alternatives and fermented vegetables show lower levels.

24 Oct 2023

Ribonucleic Acid News and Research

Placental inflammation's role in adult depression and heart disease

Pioneering study finds predictive biomarker in lung adenocarcinoma

Next-generation ovarian cancer therapy: Engineered Vδ2 T cells show promise in preclinical trials

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Cannabis use alters DNA methylation, with implications beyond smoking effects

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Immune imprinting: The crux of waning COVID-19 booster effectiveness against new variants

The association between neighborhood deprivation, DNA methylation, and gene expression in breast tissue for Black and White women with breast cancer

TIMP2 protein identified as key player in brain plasticity and memory

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Unsupervised genome-wide variant effect predictor based on pretraining of DNA language models

New omicron sublineages surge, but Pfizer-BioNTech bivalent booster retains effectiveness

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

What's really in your kombucha and kefir?

New research aims to understand the ecology of SARS-CoV-2 at the human-animal interface

Revolutionary approach links protein analysis and single-cell study to uncover disease mechanisms

The intricate interplay of stress, quality of life, and gut microbiota in newly diagnosed breast cancer patients

Resistant potato starch usage found to be feasible and safe for hematopoietic stem cell transplantation patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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