Umbilical Cord News and Research

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The umbilical cord is the structure that attaches the fetus to the placenta and acts as the medium through which nutrients, gases and waste products travel between the mother and the fetus.

C-section babies more likely to develop allergies

For expectant moms who may contemplate the pros and cons of natural child birth or Caesarian section, a Henry Ford Hospital study suggests that C-section babies are susceptible to developing allergies by age two.

25 Feb 2013

Gamida Cell announces results from NiCord Phase I/II study on hematological malignancies

Gamida Cell announced today the successful results of the Phase I/II study of its second pipeline product NiCord, umbilical cord derived stem cells expanded using the company's proprietary NAM technology.

15 Feb 2013

Paternal obesity may alter genetic mechanisms in next generations

A father's obesity is one factor that may influence his children's health and potentially raise their risk for diseases like cancer, according to new research from Duke Medicine.

6 Feb 2013

Potential connection between autism and insulin-like growth factor

A New York-based physician-researcher from Touro College of Osteopathic Medicine, best known for his research into fertility and twinning, has uncovered a potential connection between autism and a specific growth protein that could eventually be used as a way to predict an infant's propensity to later develop the disease.

2 Feb 2013

Researchers study innovative stem cell drug for treating localized cartilage damage

Rush University Medical Center is conducting the nation's first clinical study of an innovative stem cell drug, Cartistem, to repair knee cartilage damaged by aging, trauma or degenerative diseases such as osteoarthritis.

25 Jan 2013

Babies born to obese mothers have low levels of vitamin D

Women who are obese at the start of their pregnancy may be passing on insufficient levels of vitamin D to their babies, according to a new Northwestern Medicine- study.

8 Jan 2013

Umbilical cord stem cell therapy shows promise in infant BPD

Researchers have successfully used human umbilical cord stem cells to partially prevent damage and restore lung structure and function in an experimental animal model of bronchopulmonary dysplasia.

19 Dec 2012

Microarray analysis more effective in pinpointing potential genetic causes of stillbirth

Stillbirth is a tragedy that occurs in one of every 160 births in the United States. Compounding the sadness for many families, the standard medical test used to examine fetal chromosomes often can't pin down what caused their baby to die in utero. In most cases, the cause of the stillbirth is not immediately known.

6 Dec 2012

Reoperation not reliable indicator for hernia recurrence

Using reoperation rates as the indicator for recurrence after ventral hernia repair may underestimate the true recurrence rate, according to Danish study findings.

29 Nov 2012

Answers to the questions of stem cells

Next week, more than 1,200 people from 25 countries are expected to attend the 8th Annual World Stem Cell Summit in West Palm Beach, Fla., a gathering co-sponsored by Mayo Clinic. As those close to the science explore potential stem cell applications, many patients have questions about what stem cells are and how they are being used. Timothy Nelson, M.D., Ph.D., director of Mayo Clinic's Regenerative Medicine Consult Service, answers some of the most commonly asked questions about stem cells.

29 Nov 2012

Omega-3 fatty acids can benefit women at risk of postpartum depression

The "feel-good" hormone serotonin, depleted by pregnancy, can be replenished by adding sources of omega-3 to the diets of pregnant women and new mothers - a development particularly beneficial to the 10 to 15 percent of women at risk for postpartum depression, according to a recent University of Montreal study published in the latest edition of the Canadian Journal of Psychiatry.

29 Nov 2012

Researchers develop safe, feasible and robust co-culture system for hESC expansion

Researchers in Taiwan have developed a "safe, feasible and robust co-culture system" supplied by human umbilical cord mensenchymal stem cells (HUCMSCs) to feed the sustained culture used for human embryonic stem cell (hESC) expansion prior to cell transplantation.

17 Nov 2012

HUCPVC cell therapy more effective in restoring heart function after myocardial infarction

A study published this month by researchers at the University of Toronto and Toronto's Princess Margaret Hospital has shown that cells derived from the umbilical cord, "Human Umbilical Cord PeriVascular Cells" (HUCPVCs), are more effective in restoring heart function after an acute myocardial infarction (in common parlance, a heart attack) in a pre-clinical model than a similar cell population derived from bone marrow.

16 Nov 2012

Smoking affects development of peripheral allergy-relevant stem cells in the blood

Environmental contaminants, such as smoking, are harmful to the human organism in relation to the occurrence of allergies. This is known. Until now, researchers had never investigated whether and to what extent environmental contaminants also affect allergy-relevant stem cells.

15 Nov 2012

Exosomes alone could protect infants' lungs from dangerous inflammation

Researchers at Boston Children's Hospital have found that microscopic particles containing proteins and nucleic acids called exosomes could potentially protect the fragile lungs of premature babies from serious lung diseases and chronic lung injury caused by inflammation.

1 Nov 2012

Bodyguard macrophages protect stem cells from over-differentiation

Hiding deep inside the bone marrow are special cells. They wait patiently for the hour of need, at which point these blood forming stem cells can proliferate and differentiate into billions of mature blood immune cells to help the body cope with infection, for example, or extra red blood cells for low oxygen levels at high altitudes. Even in emergencies, however, the body keeps to a long-term plan: It maintains a reserve of undifferentiated stem cells for future needs and crises.

23 Oct 2012

Sickle cell disease treatments: An interview with Dr Niihara, CEO of Emmaus Medical

Sickle cell disease is a devastating hereditary condition that affects millions of people, particularly those in West and Central Africa as well as people of African descent in the United States, Europe and South America.

23 Oct 2012

New prototype mouse model duplicates the human response in rheumatoid arthritis

Researchers at Northwestern University Feinberg School of Medicine have developed the first animal model that duplicates the human response in rheumatoid arthritis (RA), an important step that may enable scientists to discover better medicines to treat the disease.

5 Oct 2012

Long-term survivors of hematopoietic cell transplants more likely to develop heart disease

New research appearing online today in Blood, the Journal of the American Society of Hematology (ASH), suggests that long-term survivors of hematopoietic cell transplants (HCT) are at an increased risk of developing heart disease risk factors such as high blood pressure, diabetes, and high cholesterol when compared to the general population.

4 Oct 2012

Study investigates time-dependent efficacy of hUCB MNCs after experimental brain ischemia

A research team from Germany has found that optimal benefit and functional improvement for ischemic stroke results when human umbilical cord blood mononuclear cells (hUCB MNCs) are transplanted into rat stroke models within 72 hours of the stroke.

3 Oct 2012

Umbilical Cord News and Research

Further Reading

C-section babies more likely to develop allergies

Gamida Cell announces results from NiCord Phase I/II study on hematological malignancies

Paternal obesity may alter genetic mechanisms in next generations

Potential connection between autism and insulin-like growth factor

Researchers study innovative stem cell drug for treating localized cartilage damage

Babies born to obese mothers have low levels of vitamin D

Umbilical cord stem cell therapy shows promise in infant BPD

Microarray analysis more effective in pinpointing potential genetic causes of stillbirth

Reoperation not reliable indicator for hernia recurrence

Answers to the questions of stem cells

Omega-3 fatty acids can benefit women at risk of postpartum depression

Researchers develop safe, feasible and robust co-culture system for hESC expansion

HUCPVC cell therapy more effective in restoring heart function after myocardial infarction

Smoking affects development of peripheral allergy-relevant stem cells in the blood

Exosomes alone could protect infants' lungs from dangerous inflammation

Bodyguard macrophages protect stem cells from over-differentiation

Sickle cell disease treatments: An interview with Dr Niihara, CEO of Emmaus Medical

New prototype mouse model duplicates the human response in rheumatoid arthritis

Long-term survivors of hematopoietic cell transplants more likely to develop heart disease

Study investigates time-dependent efficacy of hUCB MNCs after experimental brain ischemia

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