Vagina News and Research

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Fibulin-5 protein can help prevent pelvic organ prolapse development in women

Pelvic organ prolapse is a disabling condition that affects almost 50% of women over the age of 50. It occurs when the muscles and ligaments supporting a woman's pelvic organs weaken such that the pelvic organs slip out of place, often protruding into the vagina.

26 Apr 2011

Squamous cell cancers can originate from hair follicle stem cells, finds study

Squamous cell cancers, which can occur in multiple organs in the body, can originate from hair follicle stem cells, a finding that could result in new strategies to treat and potentially prevent the disease, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center and the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.

20 Apr 2011

Researchers to wind down HIV prevention trial in women after interim results find drug not offering protection from HIV

Researchers on Monday announced they were calling off a trial to test whether taking an oral HIV drug reduces the risk of HIV infection in women after interim analysis of the study showed women taking the medication were no less likely to become infected with HIV than those who were not taking the medicine, the Associated Press reports.

20 Apr 2011

First ever light-activated, non-surgical treatment for HPV and pre-cancerous lesions of the cervix

A new non-surgical, tissue-preserving therapeutic procedure is being developed to more effectively remove HPV infection and treat precursors of cervical cancer.

16 Mar 2011

Organ removal surgery through body's orifices, without any visible incisions

The Chicago Park District physical instructor needed a way to get the surgery performed without being laid up for weeks so she opted for an innovative minimally invasive procedure called Natural Orifice Translumenal Endoscopic Surgery (NOTES) that would allow surgeons to perform organ removal surgery without any visible incisions and have her back on her feet the same day.

11 Mar 2011

Tenofovir gel more effective than oral tablet for HIV treatment: Study

In the first study to make head-to-head comparisons between tenofovir gel and oral tenofovir - two promising approaches for preventing HIV in women - researchers found that daily use of the vaginal gel achieved a more than 100-times higher concentration of active drug in vaginal tissue than did the oral tablet, while, compared to the gel, the tablet used daily was associated with a 20-times higher active drug concentration in blood.

1 Mar 2011

Anti-AIDS gel shows promise

Dr. Ian McGowan, a professor of medicine at the University of Pittsburgh who is leading a second-phase study of the gel said, “These are early results, but [they] help set the stage for current and future trials of rectal microbicides and the development of a rectal-specific formulation of tenofovir gel.” Researchers have focused on the use of microbicides such as tenofovir, as a preventive treatment to be used in vaginal sex. However, scientists think unprotected anal sex is much more risky.

1 Mar 2011

Tenofovir gel may help reduce risk of HIV from anal sex

A gel developed to protect against HIV during vaginal sex produced a strong antiviral effect when used in the rectum, according to an early-phase study presented today at the 18th Conference on Retroviruses and Opportunistic Infections (CROI). The results, based on rectal tissue biopsies sampled from HIV-negative men and women who used the product daily for one week, provide the first-ever evidence that tenofovir gel could help reduce the risk of HIV from anal sex, even though the vaginal gel formulation may not be optimal for rectal use.

28 Feb 2011

ITM research provides deep insight into interactions between HIV virus and human cells

Over the years, the AIDS virus has increasingly adapted itself to humans. This is shown by the research of Youssef Gali at the Institute of Tropical Medicine.

15 Feb 2011

Proellex vaginal delivery exhibits four times activity of oral dose in animal study

Repros Therapeutics Inc. today announced it has completed two animal model studies of the use of Proellex® in a vaginally administered formulation that demonstrated effects on progesterone sensitive tissues equivalent to the highest oral dose formerly in development by the Company.

28 Dec 2010

CT best way to detect cocaine in human drug couriers

According to a study presented today at the annual meeting of the Radiological Society of North America (RSNA), the best way to detect cocaine in the body of a human drug courier, known as a mule, is through computed tomography (CT).

1 Dec 2010

Important queries about PrEP, iPrEx trial for HIV infection

The results of the iPrEx PrEP effectiveness trial of once-daily TDF/FTC (brand name Truvada) in gay men, transgender women and other men who have sex with men are a landmark in HIV prevention research.

24 Nov 2010

iPrEx oral PrEP study achieves major milestone in HIV prevention research

This is a great day in the fight against AIDS. The positive results of the iPrEx oral PrEP study are a major milestone in HIV prevention research and provide important information about how antiretroviral drugs might be used for prevention by HIV-negative people at high risk for HIV infection, said AVAC Executive Director Mitchell Warren.

24 Nov 2010

Patients with germinal center-like structures face greater risk of developing non-Hodgkin's lymphoma

Biopsying the glands that produce saliva to test for germinal center-like formation when someone is diagnosed with primary Sjögren's Syndrome can predict later development of non-Hodgkin's lymphoma, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

9 Nov 2010

Hydroxychloroquine may reduce cardiac neonatal lupus in subsequent pregnancies: Research

Women with anti-SSA/Ro antibodies and a previous child who has heart block a condition where the electrical signal that makes the heart beat is damaged may potentially decrease their risk of delivering another child with life threatening heart disease by taking hydroxychloroquine (Plaquenil), according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Atlanta.

8 Nov 2010

Patients with advanced oropharyngeal cancer caused by HPV have better chances of survival

When the human papillomavirus (HPV) is found in cancer tumours of the tonsil and base of the tongue, patients are more likely to survive following treatment.

3 Nov 2010

CIHR, Genome BC announce $5.4 million for microbiome research

The University of British Columbia today welcomed the announcement of $5.4 million in funding from the Canadian Institutes of Health Research (CIHR) and Genome British Columbia for research into how micro-organisms affect human health.

15 Oct 2010

Researchers study bacterial ecosystem to optimize women's health

A team of Canadian researchers are examining the delicate balance of bacteria and viruses in women's bodies in order to optimize women's health through their lives.

15 Oct 2010

World's third rectal microbicide trial launched in Pittsburgh

The world's third rectal microbicide trial launched in Pittsburgh, Pennsylvania today, with sites preparing to open in Boston, Massachusetts, and Birmingham, Alabama soon. Scientists will test the rectal safety and acceptability of tenofovir gel, a microbicide developed for vaginal use that has shown promise for preventing HIV through vaginal intercourse. Depending on the outcome of this new study, tenofovir gel could be further evaluated to determine if it can reduce the risk of HIV among both men and women who engage in receptive anal intercourse.

14 Oct 2010

MTN-007 phase trial evaluates vaginal microbicide to prevent rectal transmission of HIV

Tenofovir gel, a vaginal microbicide that has shown promise for preventing HIV through vaginal sex, is being tested in a new trial looking at its safety and acceptability when used rectally. The results of the study, being led by the U.S. National Institutes of Health (NIH)-funded Microbicide Trials Network (MTN), will help determine if the gel should be evaluated further for its potential to prevent HIV among both men and women who engage in receptive anal intercourse.

13 Oct 2010

Vagina News and Research

Fibulin-5 protein can help prevent pelvic organ prolapse development in women

Squamous cell cancers can originate from hair follicle stem cells, finds study

Researchers to wind down HIV prevention trial in women after interim results find drug not offering protection from HIV

First ever light-activated, non-surgical treatment for HPV and pre-cancerous lesions of the cervix

Organ removal surgery through body's orifices, without any visible incisions

Tenofovir gel more effective than oral tablet for HIV treatment: Study

Anti-AIDS gel shows promise

Tenofovir gel may help reduce risk of HIV from anal sex

ITM research provides deep insight into interactions between HIV virus and human cells

Proellex vaginal delivery exhibits four times activity of oral dose in animal study

CT best way to detect cocaine in human drug couriers

Important queries about PrEP, iPrEx trial for HIV infection

iPrEx oral PrEP study achieves major milestone in HIV prevention research

Patients with germinal center-like structures face greater risk of developing non-Hodgkin's lymphoma

Hydroxychloroquine may reduce cardiac neonatal lupus in subsequent pregnancies: Research

Patients with advanced oropharyngeal cancer caused by HPV have better chances of survival

CIHR, Genome BC announce $5.4 million for microbiome research

Researchers study bacterial ecosystem to optimize women's health

World's third rectal microbicide trial launched in Pittsburgh

MTN-007 phase trial evaluates vaginal microbicide to prevent rectal transmission of HIV

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