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Scientists unearth dual-action weapons against deadly tuberculosis

A research team has detected various substances that have a dual effect against tuberculosis: They make the bacteria causing the disease less pathogenic for human immune cells and boost the activity of conventional antibiotics / publication in ‘Cell Chemical Biology’.

4 Jan 2024

Metabolically armored CAR-T cells demonstrate lasting efficacy against solid tumors

At EPFL's School of Engineering, Professor Li Tang's Laboratory of Biomaterials for Immunoengineering has made significant strides in cancer treatment research.

4 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse.

4 Jan 2024

Diet-related inflammation may raise stroke risk, US study finds

The relationship between the dietary inflammatory index (DII) and stroke incidence.

4 Jan 2024

Combination therapy of dapagliflozin and semaglutide shows superior efficacy in type 2 diabetes management

Study demonstrates that combining dapagliflozin and semaglutide significantly improves glycemic control and other health parameters in type 2 diabetes patients, outperforming dapagliflozin alone.

3 Jan 2024

Simple technique boosts antibody delivery for treating brain diseases

The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors.

3 Jan 2024

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.

3 Jan 2024

Study maps gene network orchestrating complex process of IgG glycosylation in aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Mapping of the gene network that regulates glycan clock of ageing."

3 Jan 2024

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

3 Jan 2024

EGCG effect: Study suggests green tea compound may ease inflammatory iron deficiency

Whether a polyphenol found in green tea, reduces inflammation.

3 Jan 2024

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

Study evaluates the impact of hybrid immunity on SARS-CoV-2 antibody levels in Canadian adults, revealing that hybrid immunity, combining vaccination and recovery from infection, significantly reduces COVID-19 morbidity and mortality.

2 Jan 2024

Novel PET tracer accurately detects common cancer mutation for tailored treatment

A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy.

2 Jan 2024

New method designs high-affinity, orally bioavailable peptides

For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy.

28 Dec 2023

Plant-based fats and proteins shine in low-carb weight management

Low-carbohydrate diets comprised mostly of plant-based proteins and fats with healthy carbohydrates such as whole grains were associated with slower long-term weight gain than low-carbohydrate diets comprised mostly of animal proteins and fats with unhealthy carbohydrates like refined starches, according to a new study led by Harvard T.H. Chan School of Public Health.

27 Dec 2023

Brain bleeds in older adults linked to amyloid deposits in blood vessels

A common type of brain bleed in older adults, known as subdural hemorrhage, is associated with the presence of amyloid deposits in cerebral blood vessels, according to a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and Yale School of Medicine.

26 Dec 2023

Laboratory News and Research

Scientists unearth dual-action weapons against deadly tuberculosis

Metabolically armored CAR-T cells demonstrate lasting efficacy against solid tumors

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Unmasking the persistent threats of long-COVID's pulmonary sequelae

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Diet-related inflammation may raise stroke risk, US study finds

Combination therapy of dapagliflozin and semaglutide shows superior efficacy in type 2 diabetes management

Simple technique boosts antibody delivery for treating brain diseases

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

Study maps gene network orchestrating complex process of IgG glycosylation in aging

Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

EGCG effect: Study suggests green tea compound may ease inflammatory iron deficiency

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

Novel PET tracer accurately detects common cancer mutation for tailored treatment

New method designs high-affinity, orally bioavailable peptides

Plant-based fats and proteins shine in low-carb weight management

Brain bleeds in older adults linked to amyloid deposits in blood vessels

New drug screening system helps uncover promising target for pancreatic cancer treatments

Researchers receive two grants to study tuberculosis drug development

Brain injury markers found in the blood months after COVID-19 infection

Pittcon 2024 - Advancing Science on the West Coast eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo