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AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

AbbVie, a research-based global biopharmaceutical company, today announced it submitted a supplemental New Drug Application to the U.S. Food and Drug Administration for venetoclax in combination with a hypomethylating agent or in combination with low-dose cytarabine for the treatment of newly diagnosed patients with acute myeloid leukemia who are ineligible for intensive chemotherapy.

20 Jul 2018

PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

PureTech Health plc, a clinical-stage biopharmaceutical company developing novel medicines focused on the Brain-Immune-Gut Axis, today announced that it has entered into a multiyear collaboration with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., to advance PureTech's milk-derived exosome platform technology for the oral administration of Roche's antisense oligonucleotide platform.

20 Jul 2018

Healthy behaviors are not effective in preventing gestational diabetes in obese women

A diet and exercise regime for high-risk obese pregnant women, whilst effective in promoting a healthy lifestyle, does not prevent gestational diabetes, finds a study led by King's College London.

20 Jul 2018

Study provides insights into healthy aging of Asian-Americans

Older Asian-American immigrants are healthier and happier if they are socially active, connected to their families and communities and are able to maintain their cultural values while adapting to western culture, according to a new Rutgers study.

19 Jul 2018

Health burdens of very high risk drinking are potentially large, study reveals

In an Addiction Biology study, the estimated prevalence of very high risk drinking level (VHRDL, defined as drinking >100 g of ethanol per day) in 13 European Union countries was 0.74-0.85 percent, with a risk of disease or injury of 13.5 per 100 people with VHRDL per year.

18 Jul 2018

New study demonstrates little effect of hormone therapy on artery thickness

Heart disease is still the number one killer of US women, and hormone therapy remains a top treatment for menopause symptoms.

18 Jul 2018

Electronic system to speed up facial pain diagnosis may improve quality of life and save money

Patients with persistent facial pain are costing the economy more than £3,000 each per year, new research has revealed.

17 Jul 2018

Certain blood thinners may increase risk of bleeding in CKD patients

Certain blood thinners approved to treat atrial fibrillation may put patients with chronic kidney disease at a higher risk of bleeding, according to the results of a study in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

13 Jul 2018

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

In an unexpected discovery, UCLA researchers have found that a gene previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type.

13 Jul 2018

Pittcon invites oral and poster presentations for 2019 Technical Program

The Pittcon Program Committee is pleased to announce its call for oral and poster presentations for its 2019 Technical Program in Philadelphia. The program will run from March 17-21 as part of Pittcon, the world’s leading annual conference and exposition on laboratory science.

From Pittcon 12 Jul 2018

Differences in mouth bacteria of HIV-infected youth may increase risk of cavities

A team of scientists from The Forsyth Institute, a global leader in oral health research, in collaboration with the NIH-funded Pediatric HIV/AIDS Cohort Study, has published the results of a new study indicating that differences in the mouth bacteria of youth born with HIV may increase their risk of cavities.

11 Jul 2018

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

Researchers at the University of Alabama at Birmingham Comprehensive Diabetes Center have discovered a safe and effective novel therapy to reduce insulin requirements and hypoglycemic episodes in adult subjects with recent onset Type 1 diabetes by promoting the patient's own beta cell function and insulin production -- the first such discovery to target diabetes in this manner.

9 Jul 2018

Researchers develop simple blood test to predict likely spread of rare cancer

New QUT research has shed fresh light on how head and neck cancer spreads to other organs and researchers are developing a simple blood test to tell doctors which patients are at risk of spread long before conventional imaging can.

9 Jul 2018

Study assesses effectiveness of chlorhexidine in preventing bacteremia after tooth extraction

A large number of bacteria are present in human mouths and may pass into the blood when procedures such as the removal of a tooth are carried out. Chlorhexidine mouthwashes have a powerful antimicrobial effect, but there are opposing positions on its use in these cases.

9 Jul 2018

Direct oral anticoagulants associated with reduced risks of major bleeding

New drugs known as direct oral anticoagulants used to treat serious blood clots are associated with reduced risks of major bleeding compared with the older anti-clotting drug, warfarin, finds a study in The BMJ today.

5 Jul 2018

$Research finds link between increased vitamin K2 levels and reduced fracture rates in children$

Research finds link between increased vitamin K2 levels and reduced fracture rates in children

Children and adolescents should supplement vitamin K to benefit from its bone health properties, according to a new study published in Nutrients.

From BetterYou Ltd 5 Jul 2018

Study does not find causal association between assisted reproduction and ovarian cancer risk

Following concerns over many years that hormonal stimulation of the ovaries necessary for IVF may increase the risk of ovarian cancer, a nationwide cohort study from Denmark has now concluded that any perceived increase in risk is actually a statistical bias resulting from vigilant diagnosis at the time of treatment.

3 Jul 2018

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Can-Fite BioPharma Ltd., a biotechnology company advancing a pipeline of proprietary small molecule drugs that address cancer, liver and inflammatory diseases, today announced that U.S. researchers published scientific findings recommending development of anti-Liver Cancer Drugs based on a mechanism of action utilized by Namodenoson.

2 Jul 2018

Study: Articulation-relevant brain regions are also active in perception of language

Brain regions that are involved in the articulation of language are also active in the perception of language.

2 Jul 2018

Antioxidant-enriched vitamin may decrease exacerbations in cystic fibrosis patients

An antioxidant-enriched vitamin may decrease respiratory exacerbations in people with cystic fibrosis(CF), according to new research published online in April in the American Journal of Respiratory and Critical Care Medicine.

2 Jul 2018

Oral News and Research

AbbVie submits supplemental NDA to FDA for venetoclax to treat acute myeloid leukemia

PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

Healthy behaviors are not effective in preventing gestational diabetes in obese women

Study provides insights into healthy aging of Asian-Americans

Health burdens of very high risk drinking are potentially large, study reveals

New study demonstrates little effect of hormone therapy on artery thickness

Electronic system to speed up facial pain diagnosis may improve quality of life and save money

Certain blood thinners may increase risk of bleeding in CKD patients

UCLA researchers uncover gene that controls equilibrium of bone and fat in bone marrow

Pittcon invites oral and poster presentations for 2019 Technical Program

Differences in mouth bacteria of HIV-infected youth may increase risk of cavities

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

Researchers develop simple blood test to predict likely spread of rare cancer

Study assesses effectiveness of chlorhexidine in preventing bacteremia after tooth extraction

Direct oral anticoagulants associated with reduced risks of major bleeding

Research finds link between increased vitamin K2 levels and reduced fracture rates in children

Study does not find causal association between assisted reproduction and ovarian cancer risk

U.S. researchers recommend development of anti-cancer drugs based on mechanism of Namodenoson

Study: Articulation-relevant brain regions are also active in perception of language

Antioxidant-enriched vitamin may decrease exacerbations in cystic fibrosis patients

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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