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Study provides insight into variable impact of TBI on long-term memory

Kessler Foundation researchers have authored a new article that provides insight into the variable impact of traumatic brain injury (TBI) on long-term memory. The article, "Working memory capacity links cognitive reserve with long-term memory in moderate to severe TBI: a translational approach," was epublished ahead of print on October 7 in the Journal of Neurology (10.1007/s00415-014-7523-4).

2 Dec 2014

New approach can prevent chronic marijuana use, relieve mood, anxiety disorders

Replenishing the supply of a molecule that normally activates cannabinoid receptors in the brain could relieve mood and anxiety disorders and enable some people to quit using marijuana, a Vanderbilt University study suggests.

2 Dec 2014

U of T professor wins GSK's 2014 Discovery Fast Track Challenge devoted for cancer research

University of Toronto (U of T) Professor Tania Watts is a winner of GSK's 2014 Discovery Fast Track Challenge, which is designed to accelerate the translation of academic research into novel therapies.

2 Dec 2014

Scientists challenge prevailing view of how bowel cancer develops in the large intestine

A new study that challenges the prevailing view of how bowel cancer develops in the large intestine is published today in Nature Medicine.

2 Dec 2014

Sanford-Burnham, Mayo Clinic scientists to jointly find new treatment for resistant hypertension

Sanford-Burnham Medical Research Institute at Lake Nona and Mayo Clinic today announced that a joint team of scientists has been selected as a winner of GlaxoSmithKline's 2014 Discovery Fast Track Challenge.

2 Dec 2014

Variants of ASIC1a gene appear to be associated with panic disorder

Panic disorder is a severe form of anxiety in which the affected individual feels an abrupt onset of fear, often accompanied by profound physical symptoms of discomfort. Scientists have known from studying twins that genes contribute to the risk of panic disorder, but very little is known about which specific genes are involved.

2 Dec 2014

Fenofibrate benefits in diabetic retinopathy mediated through PPARα

Peroxisome proliferator–activated receptor α exerts protective effects on retinal pericytes, shows research that explains why fenofibrate is protective against diabetic retinopathy.

1 Dec 2014

Exome sequencing refines 46,XY DSD diagnosis

Exome sequencing can identify a likely genetic cause of 46,XY disorders of sex development in about a third of cases, report researchers.

1 Dec 2014

MD Anderson professor receives 13th annual City of Florence Prize in Molecular Sciences

Peter Friedl, M.D., Ph.D., professor of genitourinary medical oncology at The University of Texas MD Anderson Cancer Center, has received one of Italy's top scientific awards for his work in imaging and cancer growth, metastasis and therapy response.

1 Dec 2014

Promising new therapeutic strategy for chronic kidney disease

Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease's progress towards kidney failure. Now, however, a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania, has found an aspect of CKD's development that points to a promising new therapeutic strategy.

1 Dec 2014

New book explores convergence as key to stable global agricultural platform

A scientific text, Convergence of Food Security, Energy Security and Sustainable Agriculture, is now available through Springer Science+Business Media.

1 Dec 2014

EMA accepts new IMBRUVICA (ibrutinib) application for treatment of Waldenstrom's macroglobulinemia

Pharmacyclics, Inc.today announced the acceptance of a Type II variation application for IMBRUVICA (ibrutinib) by the European Medicines Agency.

1 Dec 2014

CTI BioPharma announces upcoming presentations of pacritinib data at ASH Annual Meeting

CTI BioPharma Corp. (CTI) today announced the upcoming presentations of data highlighting pacritinib, an oral multikinase inhibitor with dual activity against JAK2 and FLT3, and tosedostat, an oral selective inhibitor of aminopeptidases, at the 56th American Society of Hematology (ASH) Annual Meeting and Exposition, being held December 6-9 in San Francisco, CA.

1 Dec 2014

CCR5 receptor plays key role in driving prostate cancer metastases

Although prostate cancer can be successfully treated in many men, when the disease metastasizes to the bone, it is eventually lethal. In a study published online December 1st in the journal Cancer Research, researchers show that the receptor CCR5 best known for its role in HIV therapy, may also be involved in driving the spread of prostate cancer to the bone.

1 Dec 2014

BioNano Genomics' IrysChip V2 named Top 10 Innovations of 2014

BioNano Genomics, the leader in genome mapping, announced today that The Scientist named the Company's IrysChip™ V2 one of the Top 10 Innovations of 2014.

1 Dec 2014

New vaccine shows promise in patients with metastatic breast cancer

A breast cancer vaccine developed at Washington University School of Medicine in St. Louis is safe in patients with metastatic breast cancer, results of an early clinical trial indicate. Preliminary evidence also suggests that the vaccine primed the patients' immune systems to attack tumor cells and helped slow the cancer's progression.

1 Dec 2014

Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

One of the main obstacles to finding effective therapies for human diseases has been our limited understanding of disease pathogenesis: we lack detailed knowledge of the cellular and molecular mechanisms that lead to the development of disease.

30 Nov 2014

Plaza Centers' shareholders approve proposed rights offering

Elbit Imaging Ltd. ("Elbit" or the "Company") announced today, following its announcements dated June 23, 2014 and October 14, 2014, that its 62.25% owned subsidiary, Plaza Centers N.V. ("Plaza"), announced that Plaza's shareholders have approved the proposed rights offering (the "Rights Offering") which forms part of Plaza's restructuring plan.

29 Nov 2014

Canadian Blood Services urges Canadians to support fundraising campaign

On "Giving Tuesday," Dec. 2, Canadian Blood Services is encouraging Canadians to help build a national public cord blood bank by making a financial donation to the $12.5 million For All Canadians fundraising campaign.

29 Nov 2014

Researchers use mathematical models to predict how immune cells respond to disease

Walter and Eliza Hall Institute researchers have defined for the first time how the size of the immune response is controlled, using mathematical models to predict how powerfully immune cells respond to infection and disease.

28 Nov 2014