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Researchers identify ways to predict patients with small-cell lung cancer

Researchers for TGen Clinical Research Services at Scottsdale Healthcare (TCRS) have identified a way to predict which patients with small-cell lung cancer may be resistant to first-line chemotherapy.

18 Jan 2010

Study reveals interaction of genetic and environmental factors in the pathogenesis of Parkinson's disease

"Our study reveals the interaction of genetic and environmental factors such as dietary habits in the pathogenesis of Parkinson's disease," explained Dr. Matthias Elstner of the Neurological Clinic of LMU and Helmholtz Zentrum M-nchen, lead author of the study.

18 Jan 2010

MediSens Wireless to begin its wireless body-monitoring system clinical trials following FDA approval

MediSens Wireless, a startup company in UCLA's on-campus technology incubator at the California NanoSystems Institute, has obtained approval under federal Food and Drug Administration guidelines to begin clinical trials on its novel wireless body-monitoring system, which assesses muscle and neuromotor functions in the upper extremities.

18 Jan 2010

Scientists discover new links between inherited blindness and AHI1 gene

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine have discovered new links between a common form of inherited blindness affecting children and a gene known as Abelson helper integration site-1 (AHI1).

18 Jan 2010

Treatment for chronic hepatitis C with pegylated-interferon and ribavirin proves effective

The current standard treatment for chronic hepatitis C with pegylated-interferon (PEG-IFN) and ribavirin is effective in approximately 50%-60% of patients, so that a substantial proportion of patients remain unresponsive.

18 Jan 2010

Androgen replacement therapy may ward off heart damage, says study

A man's male hormones may ward off heart damage by helping vessels around the heart regenerate, suggest Australian researchers in a report posted January 13 in the Journal of Experimental Medicine (www.jem.org).

18 Jan 2010

Celgene acquires Gloucester Pharmaceuticals

Celgene Corporation today announced it has closed its acquisition of Gloucester Pharmaceuticals following the early termination of the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976.

18 Jan 2010

Role of H. pylori in autoimmune atrophic gastritis

Experimental animal studies have shown that H. pylori shares several antigenic regions in common with acid secreting cells in gastric mucosa. Antibodies triggered by H. pylori destroy acid secreting cells due to this antigenic mimicry.

17 Jan 2010

CSI receives authorization to begin its pivotal trial of ORBIT II

Cardiovascular Systems, Inc. (CSI), has received Food and Drug Administration (FDA) conditional Investigational Device Exemption (IDE) approval to evaluate the safety and effectiveness of its Diamondback 360® System in the treatment of calcified coronary lesions. With this conditional approval, CSI is authorized to begin its pivotal trial, ORBIT II, in early 2010 and initially enroll up to 100 patients at as many as 50 U.S. sites.

17 Jan 2010

Results from Bionovo's phase 1B clinical trial of Bezielle published

Bionovo, Inc. announced today the publication of their results from its phase 1B clinical trial of Bezielle (BZL101) for metastatic breast cancer. The results of the study are available online in Breast Cancer Research and Treatment and demonstrate that Bezielle continues to be safe and well tolerated with clinical evidence of anticancer activity in a heavily pretreated population of women diagnosed with metastatic breast cancer.

17 Jan 2010

Studies show treatment success for chronic hepatitis C may be predicted by rapid virological response

The likelihood of treatment success of 48 wk peg-interferon (PEG-IFN) plus ribavirin (RBV) therapy for chronic hepatitis C may be predicted by viral kinetics on therapy. In particular, recent studies have shown that sustained virological response (SVR) can be predicted by a rapid virological response (RVR), and an early virological response (EVR).

17 Jan 2010

Early immune response needed for 'hit-and-hide' cancer viruses

Retroviruses such as HIV and HTLV-1 don't hit-and-run, they hit-and-hide. They slip into host cells and insert their own DNA into the cell's DNA, and from this refuge they establish an infection that lasts a lifetime.

14 Jan 2010

Multimmune GmbH and Boulder Diagnostics partner to develop HSP70 lateral flow point of care test

Multimmune GmbH and Boulder Diagnostics Inc. announce today the joint development of an HSP70 lateral flow point of care test. Multimmune has discovered that many tumor types display the heat shock protein 70 (Hsp70) on the cell surface.

13 Jan 2010

Tips to prevent injuries during winter season

"There is always a risk of suffering injuries during physical activities, and skiing and snowboarding are no exception," said orthotraumatologist Wade Smith, Vice-Chairman of Orthopedics for Geisinger Health System. "Due to the nature of these sports, many of the injuries that skiers and snowboarders suffer are serious and require immediate medical attention."

13 Jan 2010

In-home virtual reality videogames improve hand function in teens with hemiplegic cerebral palsy

Remotely monitored in-home virtual reality videogames improved hand function and forearm bone health in teens with hemiplegic cerebral palsy, helping them perform activities of daily living such as eating, dressing, cooking, and other tasks for which two hands are needed.

13 Jan 2010

Work provides new insight into potential therapeutic treatments for cancer diseases

An enzyme that normally helps break down stored fats goes into overdrive in some cancer cells, making them more malignant, according to new findings by a team at The Scripps Research Institute.

13 Jan 2010

Massage Heights Houston opens new retreat in Royal Oaks area of Houston

Just in time for one of the most romantic holidays for couples -- Valentine's Day -- Massage Heights Houston opened its 11th Houston location on December 18th, 2009 in the Royal Oaks area of Houston.

13 Jan 2010

Growth hormone deficiency can lead to memory deficits later in life

Scientists have shown that early growth hormone supplementation in rats with growth hormone deficiency can prevent defects in memory developing later in adulthood. The study, published in the Journal of Endocrinology is the first to show that memory defects in adults as a result of growth hormone deficiency arising in childhood can be prevented by growth hormone treatment during adolescence.

13 Jan 2010

Researchers discover 93-gene signature associated with EGFR mutations in lung cancer tumors

Epidermal growth factor receptor (EGFR) is a validated therapeutic target for non-small cell lung cancer. Researchers have now discovered a 93-gene signature that is associated with the presence of EGFR mutations in tumors from lung cancer patients and is a favorable prognostic marker in patients with early stage lung cancer.

13 Jan 2010

Findings may pave way for significant advancements in cochlear implant technology for hearing loss

Loss of spiral ganglion neurons or hair cells in the inner ear is the leading cause of congenital and acquired hearing impairment. Researchers at the University of California, San Diego, School of Medicine and the National Institutes of Health found that Sox2, a protein that regulates stem cell formation, is involved in spiral ganglion neuron development. The study was published in the January 13 issue of the Journal of Neuroscience.

13 Jan 2010

Therapy News and Research

Researchers identify ways to predict patients with small-cell lung cancer

Study reveals interaction of genetic and environmental factors in the pathogenesis of Parkinson's disease

MediSens Wireless to begin its wireless body-monitoring system clinical trials following FDA approval

Scientists discover new links between inherited blindness and AHI1 gene

Treatment for chronic hepatitis C with pegylated-interferon and ribavirin proves effective

Androgen replacement therapy may ward off heart damage, says study

Celgene acquires Gloucester Pharmaceuticals

Role of H. pylori in autoimmune atrophic gastritis

CSI receives authorization to begin its pivotal trial of ORBIT II

Results from Bionovo's phase 1B clinical trial of Bezielle published

Studies show treatment success for chronic hepatitis C may be predicted by rapid virological response

Early immune response needed for 'hit-and-hide' cancer viruses

Multimmune GmbH and Boulder Diagnostics partner to develop HSP70 lateral flow point of care test

Tips to prevent injuries during winter season

In-home virtual reality videogames improve hand function in teens with hemiplegic cerebral palsy

Work provides new insight into potential therapeutic treatments for cancer diseases

Massage Heights Houston opens new retreat in Royal Oaks area of Houston

Growth hormone deficiency can lead to memory deficits later in life

Researchers discover 93-gene signature associated with EGFR mutations in lung cancer tumors

Findings may pave way for significant advancements in cochlear implant technology for hearing loss

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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