Immune Response News and Research

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Delaying second dose of Pfizer-BioNTech SARS-CoV-2 vaccine may be feasible in some cases

Researchers in Spain have conducted the most extensive study to date investigating the effectiveness of vaccinating healthcare workers with a single dose of the Pfizer-BioNTech vaccine to protect against coronavirus disease 2019 (COVID-19).

11 Mar 2021

People previously infected with SARS-CoV-2 may achieve immunity after one mRNA vaccine dose, finds study

A team of researchers led by Thomas W. McDade of Northwestern University suggests people who were previously infected with SARS-CoV-2, the causative agent of COVID-19, may require only one dose of the mRNA vaccine to obtain immunity.

11 Mar 2021

Is a single mRNA COVID-19 vaccine dose enough for recovered individuals?

A new study deals with the evaluation of adaptive immune response to COVID-19 vaccination in candidates who have recovered from SARS-CoV-2 infection.

11 Mar 2021

SARS-CoV-2 spike S1 subunit induces hypercoagulability

The vascular complications of the condition include a range of various coagulopathies that cause bleeding and thrombocytopenia or a hypercoagulable state. A new preprint research paper posted to the medRxiv server describes the role of a fibrinogen-related protein in inducing these clinical features of COVID-19.

10 Mar 2021

South African SARS-CoV-2 variant most problematic for BNT-162b2 vaccine

Researchers from Germany and the US investigated the efficacy of neutralizing antibodies against newer variants using serum and saliva samples obtained from groups of infected, vaccinated (with Pfizer BNT-162b2), and uninfected individuals. The researchers started this study to uncover vaccine-induced immune response and show the efficiency of antibody binding and neutralization in SARS-CoV-2 variants.

10 Mar 2021

Mosquito protein study could lead to therapeutics against deadly viruses

The mosquito protein AEG12 strongly inhibits the family of viruses that cause yellow fever, dengue, West Nile, and Zika and weakly inhibits coronaviruses, according to scientists at the National Institutes of Health (NIH) and their collaborators.

10 Mar 2021

Researchers shed light on T-cell receptor activation in response to infection

Immune cells specialize to ensure the most efficient defense against viruses and other pathogens. Researchers at the University of Basel have shed light on this specialization of T cells and shown that it occurs differently in the context of an acute and a chronic infection.

10 Mar 2021

NTU scientists design new compound that could help reduce overactive immune response

When the body detects a pathogen, such as bacteria or viruses, it mounts an immune system response to fight this invader. In some people, the immune system overreacts, resulting in an overactive immune response that causes the body to injure itself, which may prove fatal in some cases.

10 Mar 2021

mRNA COVID-19 vaccines show high efficacy in pregnancy and lactation

A reassuring study reports the immunogenicity and lack of reactogenicity of the coronavirus disease 2019 (COVID-19) vaccine when given to this group of subjects. This will contribute to the sum of knowledge about the implications of vaccination in this high-risk cohort.

10 Mar 2021

How likely is SARS-CoV-2 reinfection?

The coronavirus disease 2019 (COVID-19) pandemic has already caused over 117.6 million confirmed cases the world over. Yet, researchers debate the exact incidence of reinfection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19’s causative pathogen.

10 Mar 2021

Researchers confirm new drug development route for treating multiple sclerosis, asthma

Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.

10 Mar 2021

New compound can reduce overactivation without impairing the body's immunity response

10 Mar 2021

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

A new SARS-CoV-2 vaccine candidate, developed by giving a key protein's gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.

10 Mar 2021

New study may lead to therapeutic strategies for chronic lung disease

Scientists at Washington University School of Medicine in St. Louis have implicated a type of immune cell in the development of chronic lung disease that sometimes is triggered following a respiratory viral infection.

10 Mar 2021

Researchers discover new COVID-19 variants in three South African provinces

Variants of the coronavirus are appearing in different parts of the world, many of them spreading with alarming speed.

10 Mar 2021

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

In a recent bioRxiv* preprint paper, researchers isolated anti-RBD nanobodies from llamas and “nanomice” (they engineered to produce VHHs cloned from alpacas, dromedaries and camels).

10 Mar 2021

New study assesses the effects of one versus two doses of COVID-19 vaccine

While receiving just one dose of a two-dose SARS-CoV-2 vaccine tends to decrease infections in the short-term if it produces a strong immune response, it may increase the potential for the virus to "escape" therapies in the longer-term if one-dose vaccinal immunity is weak.

9 Mar 2021

2% of individuals carry 90% of SARS-CoV-2 virions: Study of 72,500 tests

In a new study published on the medRxiv* preprint server, researchers analyzed viral loads from pre-symptomatic and asymptomatic individuals in an extensive university surveillance program.

9 Mar 2021

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Some of Princeton's leading cancer researchers were startled to discover that what they thought was a straightforward investigation into how cancer spreads through the body -- metastasis -- turned up evidence of liquid-liquid phase separations: the new field of biology research that investigates how liquid blobs of living materials merge into each other, similar to the movements seen in a lava lamp or in liquid mercury.

9 Mar 2021

Buck scientists develop a predictive model to help identify people at risk for severe COVID-19

Researchers at the Buck Institute analyzed data from the COVID-19 Symptom Tracker app used by 3 million people in the United Kingdom, adding the use of immunosuppressant medication, use of a mobility aid, shortness of breath, fever, and fatigue to the list of symptoms and comorbidities that increase the risk for severe COVID-19.

9 Mar 2021

Immune Response News and Research

Delaying second dose of Pfizer-BioNTech SARS-CoV-2 vaccine may be feasible in some cases

People previously infected with SARS-CoV-2 may achieve immunity after one mRNA vaccine dose, finds study

Is a single mRNA COVID-19 vaccine dose enough for recovered individuals?

SARS-CoV-2 spike S1 subunit induces hypercoagulability

South African SARS-CoV-2 variant most problematic for BNT-162b2 vaccine

Mosquito protein study could lead to therapeutics against deadly viruses

Researchers shed light on T-cell receptor activation in response to infection

NTU scientists design new compound that could help reduce overactive immune response

mRNA COVID-19 vaccines show high efficacy in pregnancy and lactation

How likely is SARS-CoV-2 reinfection?

Researchers confirm new drug development route for treating multiple sclerosis, asthma

New compound can reduce overactivation without impairing the body's immunity response

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

New study may lead to therapeutic strategies for chronic lung disease

Researchers discover new COVID-19 variants in three South African provinces

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

New study assesses the effects of one versus two doses of COVID-19 vaccine

2% of individuals carry 90% of SARS-CoV-2 virions: Study of 72,500 tests

Princeton researchers discover previously unknown organelle that plays role in bone metastasis

Buck scientists develop a predictive model to help identify people at risk for severe COVID-19

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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