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Tossed medicine, delayed housing: How homeless sweeps are thwarting Medicaid’s goals

Andrew Douglass shoved his clothes and belongings into plastic trash bags as five police officers surrounded his encampment — a drab gray tent overflowing along a bustling sidewalk in the gritty Tenderloin neighborhood, where homeless people lie sprawled on public sidewalks, sometimes in drug overdoses.

16 Sep 2024

Laughter is as good as eye drops in soothing dry eyes, study finds

A study reveals laughter exercise is as effective as artificial tears for dry eye disease, improving symptoms and tear film stability without adverse effects.

16 Sep 2024

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

16 Sep 2024

Antibody-drug conjugate shows promise in treating ovarian and endometrial cancers

Studies reported at ESMO 2024 reveal new groups of women with early-stage endometrial and cervical cancers who gain clinically meaningful benefit from adding immunotherapy to current standard treatments, while a first-in-human study found 'promising' antitumor activity with a novel antibody drug conjugate (ADC) targeting the protein claudin 6 in heavily pretreated patients with ovarian and endometrial cancers.

14 Sep 2024

New cancer drug shows encouraging results in Phase I/II trial

The antibody-drug conjugate (ADC) puxitatug samrotecan (AZD8205) demonstrated a manageable safety profile consistent with similar ADCs and initial efficacy in heavily pretreated patients with advanced or metastatic solid tumors, according to interim data shared today at the 2024 European Society for Medical Oncology (ESMO) Congress by researchers from The University of Texas MD Anderson Cancer Center.

14 Sep 2024

Innovative heart valve technology could improve patient lives

Now, a team of UBC Okanagan researchers believe they have found a way to harness the strengths of both technologies in a way that could be life-changing - and life-saving - for many. Dr. Hadi Mohammadi and his fellow researchers in the Heart Valve Performance Laboratory at UBC Okanagan are focused on developing the mechanical heart valves of the future.

14 Sep 2024

Scientists develop novel technique to combat T cell exhaustion

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion. This phenomenon also hinders adoptive cell therapies, in which healthy, tumor-targeting T cells are infused into patients with cancer. A novel method to boost mitochondrial activity and charge up T cells is needed.

14 Sep 2024

Scientists develop selective therapy for tau tangles

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.

14 Sep 2024

New drug shows strong activity against brain metastases in HER2-positive breast cancer

A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer.

13 Sep 2024

Study sheds light on potential demand for psilocybin-assisted therapy for depression in the U.S.

In the wake of mounting evidence for the efficacy of psychedelic-assisted therapies, the U.S. Food and Drug Administration (FDA) is considering approving psilocybin, the active ingredient in "magic mushrooms," for treating depression in the near future.

13 Sep 2024

Semaglutide and tirzepatide significantly improve weight loss and glycemic control in type 1 diabetes

Semaglutide and tirzepatide treatment lead to significant weight loss and improve blood sugar control in individuals with type 1 diabetes (T1D) who are living with overweight or obesity, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) has found.

13 Sep 2024

Coordinated health teams may help improve outcomes for children with Trisomy 21 and heart conditions

A coordinated, multidisciplinary health care team to address the specific physical, psychological and developmental needs of children with Trisomy 21, or Down syndrome, and congenital heart disease may help children with these conditions lead longer and more productive lives, according to a new scientific statement from the American Heart Association.

13 Sep 2024

PPARs and PROTACs: A new strategy in cancer therapeutics

The growing challenge in cancer therapy lies in overcoming tumor heterogeneity, drug resistance, and associated side effects.

13 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

Trial finds no benefit of adding nivolumab to tivozanib for advanced kidney cancer

In an international multicenter randomized phase 3 clinical trial led by Dana-Farber Cancer Institute, researchers tested the addition of the immune checkpoint inhibitor (ICI) nivolumab to treatment with tivozanib for patients with advanced clear cell renal cell carcinoma, a form of kidney cancer.

13 Sep 2024

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

A new editorial was recently published in Oncotarget's Volume 15, on July 10, 2024, entitled, "The advances in targeting CD47/SIRPα "do not eat me" axis and their ongoing challenges as an anticancer therapy."

13 Sep 2024

Salt can boost antitumor responses of T cells

Elevated sodium levels in tumors boost T-cell metabolic fitness and cytotoxicity, revealing potential avenues for improving cancer therapies.

13 Sep 2024

$Hypofractionation proven safer and more convenient for breast cancer treatment$

Hypofractionation proven safer and more convenient for breast cancer treatment

Giving higher doses per fraction of radiation therapy over a shorter time after breast cancer surgery significantly reduces the risk of side effects and improves quality of life compared with a conventional schedule, finds a study published by The BMJ today.

13 Sep 2024

‘What happens three months from now?’ Mental health after Georgia High School shooting

About an hour after gunfire erupted at Apalachee High School, ambulances started arriving at nearby Northeast Georgia Medical Center Barrow with two students and two adults suffering from panic attacks and extreme anxiety, not bullet wounds.

13 Sep 2024

Significant global cardiovascular risk linked to high lipoprotein(a) levels

Review in The Lancet finds that one in five globally are at risk of contracting cardiovascular diseases, because they carry a genetic risk of high levels of a specific lipoprotein, which can be tested for and possibly treated.

12 Sep 2024

Therapy News and Research

Tossed medicine, delayed housing: How homeless sweeps are thwarting Medicaid’s goals

Laughter is as good as eye drops in soothing dry eyes, study finds

Early data shows mRNA-4359 may benefit patients with advanced solid cancers

Antibody-drug conjugate shows promise in treating ovarian and endometrial cancers

New cancer drug shows encouraging results in Phase I/II trial

Innovative heart valve technology could improve patient lives

Scientists develop novel technique to combat T cell exhaustion

Scientists develop selective therapy for tau tangles

New drug shows strong activity against brain metastases in HER2-positive breast cancer

Study sheds light on potential demand for psilocybin-assisted therapy for depression in the U.S.

Semaglutide and tirzepatide significantly improve weight loss and glycemic control in type 1 diabetes

Coordinated health teams may help improve outcomes for children with Trisomy 21 and heart conditions

PPARs and PROTACs: A new strategy in cancer therapeutics

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Trial finds no benefit of adding nivolumab to tivozanib for advanced kidney cancer

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

Salt can boost antitumor responses of T cells

Hypofractionation proven safer and more convenient for breast cancer treatment

‘What happens three months from now?’ Mental health after Georgia High School shooting

Significant global cardiovascular risk linked to high lipoprotein(a) levels

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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