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Combination regimen improves overall survival in certain patients with AML

A combination regimen of venetoclax and azacitidine was safe and improved overall survival (OS) over azacitidine alone in certain patients with acute myeloid leukemia (AML), according to the Phase III VIALE-A trial led by The University of Texas MD Anderson Cancer Center.

12 Aug 2020

Researchers determine the effects of after-hours cannabis use on workplace performance

Although it has become increasingly accepted for medical and recreational use, cannabis is still considered among one of the most widely used illegal substances in the United States and in many European countries.

12 Aug 2020

Study identifies factors that influence women's decisions regarding therapy options

Removal of the ovaries before natural menopause (surgical menopause) often exacerbates menopause symptoms and places women at increased risk for heart disease, osteoporosis, and cognitive decline.

12 Aug 2020

SARS-CoV-2 a "swarm" of mutant viruses

In this new study, the virus was serially passaged in independent cell types in a controlled environment. The researchers found that the virus rapidly adapts to the changing conditions in culture by selecting for pre-existing species.

12 Aug 2020

New technology could serve as more reliable model of amyotrophic lateral sclerosis

A new study published today demonstrates that a technology developed at the University of Central Florida could serve as a more reliable clinically-based model of amyotrophic lateral sclerosis (ALS) and a better screening tool for novel therapies than currently use preclinical models.

12 Aug 2020

Opioid risk is higher for patients transitioning to skilled nursing facilities

Hospital patients discharged to skilled nursing facilities often bring a high-dose painkiller prescription with them, suggesting more attention should be paid to opioid safety for those patients, research from the Oregon State University College of Pharmacy shows.

11 Aug 2020

SARS-CoV-2 infection and transmission possible in North American deer mice

The current COVID-19 pandemic began as a zoonosis in China, at the end of 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel betacoronavirus with significant similarity to an earlier virus of the same family.

11 Aug 2020

Researchers document increasing frequency, cost, and severity of gunshot wounds

The rise in firearm violence has coincided with an increase in the severity of injuries firearms inflict as well as the cost of operations to treat those injuries; policy makers must be more aggressive in addressing violence to curb these trends, researchers report in a large national study of gunshot wounds that appears as an "article in press" on the Journal of the American College of Surgeons website ahead of print.

10 Aug 2020

HPV type may impact cervical cancer characteristics and prognosis

An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumors caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics and prognosis.

10 Aug 2020

Kids with silent malaria remain vulnerable to developing endemic Burkitt lymphoma

A study has found strong similarities between children with endemic Burkitt lymphoma — an aggressive cancer that attacks the body's defense system and children with silent malaria infection.

10 Aug 2020

Stress-induced activity in the brain region may predict chest pain in people with coronary artery disease

Stress-induced activity in the inferior frontal lobe of the brain may have a direct correlation with chest pain among people with coronary artery disease.

10 Aug 2020

USA the source of most of New Zealand's coronavirus cases

New Zealand, an island country in the southwestern Pacific Ocean, is marked by its early and fierce determination to totally arrest the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the viral illness that is causing the current COVID-19 pandemic.

9 Aug 2020

Encouraging results from Phase I NovaVax SARS-CoV-2 nanoparticle vaccine trial

NVX-CoV2373, a recombinant nanoparticle vaccine developed by Novavax and manufactured at Emergent Biosolutions, was found to be well tolerated and immunogenic – inducing T-cell response and neutralization antibodies four-fold higher than the mean observed in hospitalized coronavirus disease (COVID-19) patients, shows a recent study available on the medRxiv* preprint server.

9 Aug 2020

Parental views of lay theories influence children's diet and their food preferences

Young children naturally like sugar and salt in food and develop food preferences based on what their parents serve them, but new research suggests that how parents view self-regulation also is a contributing factor.

7 Aug 2020

New brain study could make it easier to monitor people with sleep disorders

When we dream, our brains are filled with noisy electrical activity that looks nearly identical to that of the awake brain.

7 Aug 2020

Study shows recombination among SARS-CoV-2 strains is already occurring, but remains rare

A recent study by U.S. researchers, currently available on the bioRxiv preprint server, indicates that the recombination events among the viral strains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are already occurring – however, considering current levels of viral genetic diversity, they are neither widespread nor readily detectable.

6 Aug 2020

Individual’s alpha wave frequency can be used as reliable pain indicator, shows study

Rhythms produced by the brain can reliably be used to predict how sensitive we are to pain, new research shows.

6 Aug 2020

Study could refine treatment recommendations for younger adult patients with acute leukemia

The findings of a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) could refine an important set of prognostic and treatment recommendations for younger adult patients with acute myeloid leukemia (AML.

6 Aug 2020

Study reveals changes in transmissibility of SARS-CoV-2 due to D614G spike mutation

A recent research endeavor from the UK, currently available on the medRxiv preprint server, indicates that spike 614G variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) increases in frequency relative to 614D variant in a selective advantage manner – but without higher coronavirus disease (COVID-19) mortality rates.

5 Aug 2020

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

The Myelodysplastic Syndromes Group of Josep Carreras Leukaemia Research Institute, led by Dr. Francesc Solé, has participated in the first international study that confirms that having two mutated copies of the TP53 gene, as opposed to a single mutated copy, is associated with a worse prognosis in patients diagnosed with myelodysplastic syndrome (MDS).

4 Aug 2020

Frequency News and Research

Combination regimen improves overall survival in certain patients with AML

Researchers determine the effects of after-hours cannabis use on workplace performance

Study identifies factors that influence women's decisions regarding therapy options

SARS-CoV-2 a "swarm" of mutant viruses

New technology could serve as more reliable model of amyotrophic lateral sclerosis

Opioid risk is higher for patients transitioning to skilled nursing facilities

SARS-CoV-2 infection and transmission possible in North American deer mice

Researchers document increasing frequency, cost, and severity of gunshot wounds

HPV type may impact cervical cancer characteristics and prognosis

Kids with silent malaria remain vulnerable to developing endemic Burkitt lymphoma

Stress-induced activity in the brain region may predict chest pain in people with coronary artery disease

USA the source of most of New Zealand's coronavirus cases

Encouraging results from Phase I NovaVax SARS-CoV-2 nanoparticle vaccine trial

Parental views of lay theories influence children's diet and their food preferences

New brain study could make it easier to monitor people with sleep disorders

Study shows recombination among SARS-CoV-2 strains is already occurring, but remains rare

Individual’s alpha wave frequency can be used as reliable pain indicator, shows study

Study could refine treatment recommendations for younger adult patients with acute leukemia

Study reveals changes in transmissibility of SARS-CoV-2 due to D614G spike mutation

Study identifies impact of gene mutations on severity of myelodysplastic syndrome

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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