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AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Five University of California, San Diego scientists and professors are among the first class of the Fellows of the American Association for Cancer Research Academy, created to recognize researchers whose scientific contributions have propelled significant innovation and progress against cancer.

29 Mar 2013

Exposure to multiple estrogen-mimicking chemicals distorts hormone action

For years, scientists have been concerned about chemicals in the environment that mimic the estrogens found in the body. In study after study, researchers have found links between these "xenoestrogens" and such problems as decreased sperm viability, ovarian dysfunction, neurodevelopmental deficits and obesity.

29 Mar 2013

MD Anderson researchers named Fellows to new AACR academy

Five researchers and leaders from The University of Texas MD Anderson Cancer Center have been named Fellows to a new academy launched by the world's oldest and largest organization dedicated to cancer research, the American Association for Cancer Research.

29 Mar 2013

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.

29 Mar 2013

A new strategy to protect against HIV infection

An effective vaccine against HIV-1 remains elusive, but one promising strategy focuses on designer antibodies that have much broader potency than most normal, exquisitely specific antibodies.

29 Mar 2013

Research shows certain cells take on new identities through reprogramming mechanism

Researchers have been able to reprogram cells experimentally, but few have shown that cells can change their identities under normal physiological conditions in the body, particularly in mammals.

29 Mar 2013

Study: Hormone-therapy-related breast cancer cells can be attacked by cancer therapies

More than 100 women per day die from breast cancer in the United States. The odds of developing breast cancer increase for women taking hormone replacement therapy to avoid the effects of menopause.

28 Mar 2013

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Inflammation can be thought of as taking two major forms: acute or chronic. Acute inflammation, which can be painful, usually arises quickly and resolves quickly. It accompanies bacterial infections, traumatic injury and is useful to fight infections and promote healing.

28 Mar 2013

Phase 2 study of REOLYSIN meets primary endpoint in patients with squamous cell lung cancer

Oncolytics Biotech Inc. today announced that it has met the primary overall statistical endpoint in its U.S. Phase 2 single arm clinical trial in patients with squamous cell carcinoma of the lung using intravenous administration of REOLYSIN in combination with carboplatin and paclitaxel in patients with metastatic stage IIIB, or stage IV, or recurrent SCCLC who are chemotherapy naïve for their metastatic or recurrent cancer (REO 021).

28 Mar 2013

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Amarantus BioScience, Inc., a biotechnology company discovering and developing treatments and diagnostics for diseases associated with neurodegeneration and apoptosis, today reported positive preclinical data for its lead therapeutic MANF in neuroprotection 6-hydroxydopamine (6-OHDA) rat models of Parkinson's disease.

28 Mar 2013

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

It's been more than 50 years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined.

28 Mar 2013

Research findings could lead to improved treatment for neuropathic pain

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery of peripheral nerves after injury.

28 Mar 2013

Neurological researchers study promising new treatment for deadly brain tumors

A promising new treatment for deadly brain tumors taken orally with minimal side effects is being studied by neurological researchers at Rush University Medical Center, Chicago.

28 Mar 2013

Exosomes can transfer membrane proteins, study reveals

Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting discovery that means these tiny vehicles could one day be loaded with therapeutic agents, such as RNA interference, and directly target disease-carrying cells.

28 Mar 2013

Environmental enrichment increases endogenous cell migration, facilitates functional repair

A team of Korean researchers investigated whether "environmental enrichment" can improve the neurobehavioral function of six week-old mice after transplantation of adipose-derived stem cells to treat hypoxic-ischemic brain injury, and found that brain repair (neurogenesis) was aided in some animals through exercise-induced fibroblast growth factor 2 (FGF2), a strong pro-angiogenic factor.

28 Mar 2013

Researchers shed new light on role of methylation in gene expression

Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed.

28 Mar 2013

Virginia G. Piper Cancer Center Clinical Trials successfully tests cabozantinib

The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute.

28 Mar 2013

New laboratory study shows certain protein particles multiply, spread from one cell to another

In diseases like Alzheimer's and Parkinson's endogenous proteins accumulate in the brain, eventually leading to the death of nerve cells. These deposits, which consist of abnormally formed proteins, are supposed to migrate between interconnected areas of the brain, thereby contributing to the development of the illness.

28 Mar 2013

Tecfidera gets FDA approval for adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Tecfidera (dimethyl fumarate) capsules to treat adults with relapsing forms of multiple sclerosis.

28 Mar 2013

New study associates commonly used diabetes drugs with pancreatic cancer risk

ndividuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine tumors, according to a new study by researchers from UCLA and the University of Florida.

28 Mar 2013

B Cell News and Research

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Exposure to multiple estrogen-mimicking chemicals distorts hormone action

MD Anderson researchers named Fellows to new AACR academy

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

A new strategy to protect against HIV infection

Research shows certain cells take on new identities through reprogramming mechanism

Study: Hormone-therapy-related breast cancer cells can be attacked by cancer therapies

Inflammation and epigenetics: an interview with Dr Belkina and Dr Denis, Boston University School of Medicine

Phase 2 study of REOLYSIN meets primary endpoint in patients with squamous cell lung cancer

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

Research findings could lead to improved treatment for neuropathic pain

Neurological researchers study promising new treatment for deadly brain tumors

Exosomes can transfer membrane proteins, study reveals

Environmental enrichment increases endogenous cell migration, facilitates functional repair

Researchers shed new light on role of methylation in gene expression

Virginia G. Piper Cancer Center Clinical Trials successfully tests cabozantinib

New laboratory study shows certain protein particles multiply, spread from one cell to another

Tecfidera gets FDA approval for adults with relapsing forms of MS

New study associates commonly used diabetes drugs with pancreatic cancer risk

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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