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Results from Phase II START study published in The Lancet Diabetes & Endocrinology

Results from the START clinical study (Study of Thymoglobulin to Arrest Newly Diagnosed Type 1 Diabetes), led by Dr. Steve Gitelman (University of California, San Francisco) and sponsored by the Immune Tolerance Network, are published today in The Lancet Diabetes & Endocrinology.

28 Aug 2013

Researchers develop ddPCR technology to quantify rejection biomarker in organ transplant injury

A recently reported blood test for the early detection of organ transplant injury could enable more timely therapeutic intervention in transplant patients and thus help to avoid longer term damage. As described by scientists at the University Medical Center G-ttingen and Chronix Biomedical, a molecular diagnostics company, the new method uses Bio-Rad Laboratories' Droplet Digital PCR (ddPCR-) technology to overcome the obstacles of earlier tests, which were both time-consuming and costly.

28 Aug 2013

Study shows ABL kinases have enhanced expression and activity in CML

Chronic Myelogenous Leukemia (CML) is a cancer of the white blood cells that is most commonly found in adults and in the elderly. Its incidence has been estimated to be 1 to 2 in 100,000 people. CML was the first cancer to be associated with a genetic abnormality, known as the Philadelphia Chromosome, which 95% of all CML patients carry in their cells.

28 Aug 2013

UTHealth researchers find cause for rare type of bleeding disorder

Fifteen years ago, a hematologist came to Dianna Milewicz, M.D., Ph.D., with a puzzle: Multiple generations of an East Texas family suffered from a moderately severe bleeding disorder, but it wasn't hemophilia.

28 Aug 2013

New technique using ice slush and robotic surgery to remove large kidney stone

A first-ever technique using ice slush and minimally invasive robotic surgery to remove a particularly large type of kidney stone has been reported by urologists at Henry Ford Hospital.

28 Aug 2013

Combining fecal immunological test and colonoscopy may improve detection of colorectal cancer

A strategy that combines two effective colorectal cancer screening methods, fecal immunological test and colonoscopy, may improve prevention and detection of colorectal cancer and reduce costs, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

28 Aug 2013

Personalised management: The only way to close mortality gap for AF patients

Personalised management is the only way to close the mortality gap for patients with atrial fibrillation, according to an ESC consensus paper presented at ESC Congress 2013 by Professor Paulus Kirchhof (UK).

27 Aug 2013

Research finding could lead to potential treatment for lymphedema

The molecule interleukin-7 is an important immune messenger protein which ensures that a sufficient number of T cells are present in our body for immune defence. Researchers from ETH Zurich have now demonstrated that IL-7 has another important function: it enhances the drainage function of lymphatic vessels, which collect fluid that has leaked out of blood vessels into the body tissue and return it to the bloodstream.

27 Aug 2013

Implementation of better blood-management plan changes culture at UAB

Blood is in big demand at the University of Alabama at Birmingham Hospital, once the fourth largest user of blood among U.S. hospitals served by the American Red Cross. And although blood transfusions can be life-saving during cancer care, trauma, surgery, transplants and difficult pregnancies, supply doesn't always rise to meet demand.

27 Aug 2013

Northwestern surgical oncologists use minimally invasive procedure to remove malignant melanoma

That's when she received the results from her dermatologist, who removed a part of the blister and had it tested. It turns out that little red bump was malignant melanoma, the leading cause of skin cancer death in the United States. It's a cancer that kills one person every hour, which translates to more than 8,700 Americans each year.

27 Aug 2013

HIV-infected people who carry gene face greater risk of contracting cryptococcal disease

HIV-infected people who carry a gene for a specific protein face a 20-fold greater risk of contracting cryptococcal disease, according to a study published in mBio-, the online open-access journal of the American Society for Microbiology.

27 Aug 2013

Weight-management intervention effective for weight gain prevention among black women

An intervention not focused on weight loss was effective for weight gain prevention among socioeconomically disadvantaged black women, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

27 Aug 2013

Intracerebral injection of BSC may reduce post-stroke cognitive dysfunction

Cognitive deficits following ischemic stroke are common and debilitating, even in the relatively few patients who are treated expeditiously so that clots are removed or dissolved rapidly and cerebral blood flow restored.

27 Aug 2013

Risk of kidney stones increasing among women

The risk of women developing kidney stones is rising, as is the number of cases being seen in U.S. emergency departments, while the rate of hospitalization for the disorder has remained stable.

27 Aug 2013

Mount Sinai scientists receive NIH grant to study clinical benefit of IGF-1 in children with PMS

Scientists at the Seaver Autism Center at the Icahn School of Medicine at Mount Sinai have received a grant from the National Institutes of Health to study Insulin-Like Growth Factor-1, a promising treatment for a subtype of autism called Phelan McDermid Syndrome.

27 Aug 2013

Examining cost: Why are health care services so expensive?

The New York Times looks at the cost of care and asks why it's so difficult for consumers to find out what a service costs. In the meantime, new research shows ending copays and making medication easier to use drives lower rates of hypertension.

27 Aug 2013

Microscopic material in cells offers robust treatment for stroke

In the latest in a series of experiments testing the use of stem cells to treat neurological disease, researchers at Henry Ford Hospital have shown for the first time that microscopic material in the cells offers a "robust" treatment for crippling stroke.

27 Aug 2013

Powerful new option for treating vasculitis

In a study published in the New England Journal of Medicine, a research consortium that includes the University of Alabama at Birmingham (UAB) has shown that a new drug for vasculitis, a potentially life-threatening auto-immune disease which causes inflammation in blood vessels, is as effective as standard therapy over 18 months.

27 Aug 2013

Oxygen-generating compound could preserve muscle tissue after severe injury

The same compound in a common household clothes detergent shows promise as a treatment to preserve muscle tissue after severe injury. Researchers at the Wake Forest Baptist Medical Center's Institute for Regenerative Medicine hope the oxygen-generating compound could one day aid in saving and repairing limbs and tissue.

27 Aug 2013

UAB study points to protein pathway that could lead to new treatments for diabetes

The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham study published online today in the journal Nature Medicine.

27 Aug 2013

Blood News and Research

Results from Phase II START study published in The Lancet Diabetes & Endocrinology

Researchers develop ddPCR technology to quantify rejection biomarker in organ transplant injury

Study shows ABL kinases have enhanced expression and activity in CML

UTHealth researchers find cause for rare type of bleeding disorder

New technique using ice slush and robotic surgery to remove large kidney stone

Combining fecal immunological test and colonoscopy may improve detection of colorectal cancer

Personalised management: The only way to close mortality gap for AF patients

Research finding could lead to potential treatment for lymphedema

Implementation of better blood-management plan changes culture at UAB

Northwestern surgical oncologists use minimally invasive procedure to remove malignant melanoma

HIV-infected people who carry gene face greater risk of contracting cryptococcal disease

Weight-management intervention effective for weight gain prevention among black women

Intracerebral injection of BSC may reduce post-stroke cognitive dysfunction

Risk of kidney stones increasing among women

Mount Sinai scientists receive NIH grant to study clinical benefit of IGF-1 in children with PMS

Examining cost: Why are health care services so expensive?

Microscopic material in cells offers robust treatment for stroke

Powerful new option for treating vasculitis

Oxygen-generating compound could preserve muscle tissue after severe injury

UAB study points to protein pathway that could lead to new treatments for diabetes

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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