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New consortium tackles genetic origins of neurodevelopmental and psychiatric disorders

Neurodevelopmental and psychiatric disorders (NPD) including schizophrenia, bipolar disorder, autism, and depression are detrimental to individuals, their families and society as a whole, and in many cases still lack effective treatments.

12 Sep 2024

Current and emerging biomarkers in the management of inflammatory bowel disease

Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disorder of the gastrointestinal (GI) tract that significantly impacts the quality of life of patients.

12 Sep 2024

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

12 Sep 2024

New discovery offers hope for overcoming CAR-T cell therapy resistance

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

12 Sep 2024

B cell abnormalities identified as potential biomarkers for triple negative breast cancer treatment response

Researchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell changes in blood and bone marrow of triple negative breast cancer patients.

12 Sep 2024

Nucleophagy identified as key DNA repair mechanism in cancer treatments

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is particularly relevant for patients undergoing colorectal cancer treatments.

12 Sep 2024

New research aims to target IL-6 for treating diabetic retinopathy

Scientists at the Medical College of Georgia at Augusta University are searching for a new treatment target for a common complication of diabetes that can cause retinal blood vessels to break down, leak, or become blocked.

12 Sep 2024

Five key factors identified for predicting immunotherapy response in cancer patients

Immunotherapy has transformed cancer treatment in recent years by enabling the immune system to attack tumor cells.

12 Sep 2024

QB3-led team awarded $12 million to explore autism origins with advanced models

A QB3-led team uniting researchers from the University of California campuses at Berkeley, San Francisco, and Santa Cruz was awarded a $12 million grant from the California Institute for Regenerative Medicine (CIRM) to investigate the origins of autism using sophisticated cellular models called "neural organoids."

12 Sep 2024

Sickle cell trait increases risk of blood clots across diverse ancestries

National Institutes of Health (NIH) researchers and collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk that is the same among diverse human populations that may not traditionally be associated with sickle cell disease.

12 Sep 2024

AI tool enhances cancer diagnosis by transforming standard tissue images

VirtualMultiplexer transforms histology images into detailed cancer markers, streamlining diagnostics and enhancing patient outcomes through AI innovation.

12 Sep 2024

Researchers uncover why typically normal protein drives prostate cancer

NSD-2 is crucial for AR activity in prostate cancer, promoting tumor growth and offering a potential therapeutic target for advanced prostate cancer treatment.

12 Sep 2024

MSK researchers identify a new, rare type of small cell lung cancer

A team of doctors and researchers at Memorial Sloan Kettering Cancer Center (MSK) have identified a new, rare type of small cell lung cancer that primarily affects younger people who have never smoked.

11 Sep 2024

Microcins offer promising new approach to treating cholera

More than a million people each year die from infections by pathogens that are resistant to antimicrobials, and the problem is growing.

11 Sep 2024

Ropirio Therapeutics secures exclusive license for novel lymphatic system activators

The Wyss Institute at Harvard University announced today that Ropirio Therapeutics, Inc. (Ropirio) has secured a worldwide, exclusive license from Harvard's Office of Technology Development (OTD) and Boston University (BU)'s Technology Development office for novel molecules that activate the lymphatic system - a first in the pharma industry.

11 Sep 2024

Study reveals shared and unique molecular markers across multiple forms of dementia

Researchers have for the first time identified degeneration-associated "molecular markers" – observable changes in cells and their gene-regulating networks – that are shared by several forms of dementia that affect different regions of the brain.

11 Sep 2024

Scripps Research develops breakthrough technique for adding unique amino acids to proteins

It's a dogma taught in every introductory biology class: Proteins are composed of combinations of 20 different amino acids, arranged into diverse sequences like words.

11 Sep 2024

2-bromopalmitate reduces senescence phenotype in human cells by modulating palmitoylation

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 16 on August 23, 2024, entitled, "2-Bromopalmitate treatment attenuates senescence phenotype in human adult cells - possible role of palmitoylation."

11 Sep 2024

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

The c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an acceptable safety profile in patients of Asian race with c-Met protein-overexpressing, epidermal growth factor receptor (EGFR) wildtype (WT), locally advanced/metastatic nonsquamous non-small cell lung cancer (NSCLC), according to research presented today at the International Association for the Study of Lung Cancer's 2024 World Conference on Lung Cancer.

11 Sep 2024

Study shows CAR T-cell therapy's risk of second primary malignancies comparable to other treatments

The frequency of second primary malignancies (SPMs) arising in cancer survivors following treatment with CAR T-cell therapy was statistically comparable to the frequency of SPMs following other standard-of-care therapies, according to a systematic review and meta-analysis.

11 Sep 2024

B Cell News and Research

New consortium tackles genetic origins of neurodevelopmental and psychiatric disorders

Current and emerging biomarkers in the management of inflammatory bowel disease

Early Phase I data shows promise for mRNA cancer immunotherapy in advanced solid cancers

New discovery offers hope for overcoming CAR-T cell therapy resistance

B cell abnormalities identified as potential biomarkers for triple negative breast cancer treatment response

Nucleophagy identified as key DNA repair mechanism in cancer treatments

New research aims to target IL-6 for treating diabetic retinopathy

Five key factors identified for predicting immunotherapy response in cancer patients

QB3-led team awarded $12 million to explore autism origins with advanced models

Sickle cell trait increases risk of blood clots across diverse ancestries

AI tool enhances cancer diagnosis by transforming standard tissue images

Researchers uncover why typically normal protein drives prostate cancer

MSK researchers identify a new, rare type of small cell lung cancer

Microcins offer promising new approach to treating cholera

Ropirio Therapeutics secures exclusive license for novel lymphatic system activators

Study reveals shared and unique molecular markers across multiple forms of dementia

Scripps Research develops breakthrough technique for adding unique amino acids to proteins

2-bromopalmitate reduces senescence phenotype in human cells by modulating palmitoylation

Telisotuzumab vedotin shows promising results in asian patients with c-Met overexpressing NSCLC

Study shows CAR T-cell therapy's risk of second primary malignancies comparable to other treatments

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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