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High levels of social support may protect brain during stroke

New research in mice suggests that high levels of social support may provide some protection against strokes by reducing the amount of damaging inflammation in the brain.

18 Nov 2008

Neuralstem enters stem cell collaboration for Huntington's disease in Germany

Neuralstem, Inc. announced today that it has entered into a collaboration with Professor Guido Nikkah Ph.D, of Albert-Ludwigs-University in Freiburg, Germany, to advance development of Neuralstem's human neural stem cell therapies.

18 Nov 2008

Maas Biolab scientists validate cyclosporin human neuroprotection

Maas Biolab researchers CSO Eskil Elmer, M.D., Ph.D. and neuroscientist Magnus Hansson, M.D., Ph.D., and colleagues have for the first time ever demonstrated the mitochondrial permeability transition (mPT) or "megapore" occurs in viable adult human neuron mitochondria and the ability of cyclosporin-A to block its formation.

18 Nov 2008

A link found between nicotine addiction and autism

Scientists have identified a relationship between two proteins in the brain that has links to both nicotine addiction and autism.

17 Nov 2008

New evidence on how proteins help cells fix broken DNA

Aucott et al. report the first in vivo experiments on the heterochromatin protein 1 (HP1) family, which sidles up to silent DNA.

17 Nov 2008

Glucocorticoids may cause damage in the brain

A class of drugs that are used in premature infants to treat chronic lung damage can cause damage in the brain.

17 Nov 2008

Seniors with sharp brains reveal first secrets of sharp memory in old age

Maybe you have an 85-year-old grandfather who still whips through the newspaper crossword puzzle every morning or a 94-year-old aunt who never forgets a name or a face.

16 Nov 2008

New research reveals key steps in HIV's assault on the brain

Scientists have unraveled in unprecedented detail the cascade of events that go wrong in brain cells affected by HIV, a virus whose assault on the nervous system continues unabated despite antiviral medications that can keep the virus at bay for years in the rest of the body.

16 Nov 2008

New clue for cellular damage in Huntington's disease

"Huntington's disease presents an ideal vantage point to study neurodegenerative disease, because we know the misfolded protein that's responsible," says Martin Duennwald, formerly a postdoctoral researcher in the lab of Whitehead Member Susan Lindquist.

16 Nov 2008

Breakthrough in cellular analysis

Like skilled assassins, many diseases seem to know exactly what types of cells to attack.

16 Nov 2008

Breakthrough in cell-type analysis offers new ways to study development and disease

Like skilled assassins, many diseases seem to know exactly what types of cells to attack. While decimating one cadre of cells, diseases will inexplicably spare a seemingly identical group of neighbors. What makes cells vulnerable or not depends largely on the kinds and amounts of proteins they produce - their 'translational profile,' in the lingo of molecular biology. For this reason, scientists have struggled to parse the subtle molecular differences among the hundreds of specialized cell types that are tangled together in tissues like the brain.

13 Nov 2008

Light triggers a new chemical code for brain cells

Brain cells can adopt a new chemical code in response to cues from the outside world, scientists working with tadpoles at the University of California, San Diego report in the journal Nature this week.

12 Nov 2008

Discovery of essential mechanism for maintenance of myelin's structure

In a new study, researchers at the Montreal Neurological Institute (MNI), McGill University, and the University of Montreal have discovered an essential mechanism for the maintenance of the normal structure of myelin, the protective covering that insulates and supports nerve cells (neurons).

12 Nov 2008