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Scientists identify potential treatment for idiopathic pulmonary fibrosis

Investigators at the University of Alabama at Birmingham (UAB) have unlocked another piece of the puzzle surrounding idiopathic pulmonary fibrosis, an often fatal lung disease with no cure and no effective treatments.

25 Mar 2013

Researchers expand hematopoietic stem cells for bone marrow transplantation

More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.

25 Mar 2013

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not previously been linked to the disease.

25 Mar 2013

Protein with key job in muscle function moonlights in nucleus to help regulate genes

A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.

25 Mar 2013

Study investigates new way to treat necrotizing enterocolitis

Stem cells taken from amniotic fluid were used to restore gut structure and function following intestinal damage in rodents, in new research published in the journal Gut.

25 Mar 2013

Study uncovers new relationship between nuclear architecture, gene activity

Every time a cell divides it makes a carbon copy of crucial ingredients, including the histone proteins that are responsible for spooling yards of DNA into tight little coils.

25 Mar 2013

Study reveals role of SNX27 protein in brain function

What is it about the extra chromosome inherited in Down syndrome-chromosome 21-that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute have new evidence that points to a protein called sorting nexin 27, or SNX27.

25 Mar 2013

Experts outline new agenda for inflammatory bowel disease research

Every five years, the Crohn's & Colitis Foundation of America gathers top researchers in inflammatory bowel disease to set the research agenda for the next five years.

25 Mar 2013

Researchers study how nerve cells repair themselves after injury

One molecule makes nerve cells grow longer. Another one makes them grow branches. These new experimental manipulations have taken researchers a step closer to understanding how nerve cells are repaired at their farthest reaches after injury.

25 Mar 2013

Researchers identify patterns of mutations in early stage node negative lung adenocarcinoma

Molecular driven therapeutic targets have resulted in a paradigm shift in the treatment of advanced lung adenocarcinoma. However, in early non-small cell lung cancer, surgical resection remains the treatment of choice with adjuvant chemotherapy.

25 Mar 2013

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Collaborating scientists from Nationwide Children's Hospital, Baylor Institute for Immunology Research, and Mount Sinai School of Medicine have identified an important mechanism for stimulating protective immune responses following seasonal influenza vaccinations.

25 Mar 2013

Researchers identify a new approach for treating brain metastases associated with lung cancer

Lung cancer is the world's most common cause of death from cancer. In Austria, around 4,000 people develop this type of cancer every year. One particular problem is the development of brain metastases in association with the lung tumour.

24 Mar 2013

SLU researcher studies effect of bitter melon extract on treating cancer

A Saint Louis University researcher has received a $39,425 grant from the Lottie Caroline Hardy Charitable Trust to continue her research on treating cancer with a natural substance -- the extract taken from a vegetable that is part of her diet.

24 Mar 2013

Study of genetically modified immune cells could help improve promising treatment for melanoma

A new study of genetically modified immune cells by scientists from UCLA and the California Institute of Technology could help improve a promising treatment for melanoma, an often fatal form of skin cancer.

24 Mar 2013

Translational Research's April issue examines progress, outlook of gene therapy research

The April issue of Translational Research examines the progress and outlook of gene therapy research, with a specific focus on the clinical applicability of gene therapy today.

22 Mar 2013

Fralin Life Science Institute researchers use TALENS to alter mosquito genome

Virginia Tech researchers successfully used a gene disruption technique to change the eye color of a mosquito - a critical step toward new genetic strategies aimed at disrupting the transmission of diseases such as dengue fever.

22 Mar 2013

MU researchers redefine key regulatory process in defective protein responsible for cystic fibrosis

A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future.

22 Mar 2013

B Cell News and Research

Scientists identify potential treatment for idiopathic pulmonary fibrosis

Researchers expand hematopoietic stem cells for bone marrow transplantation

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

Protein with key job in muscle function moonlights in nucleus to help regulate genes

Study investigates new way to treat necrotizing enterocolitis

Study uncovers new relationship between nuclear architecture, gene activity

Study reveals role of SNX27 protein in brain function

Experts outline new agenda for inflammatory bowel disease research

Researchers study how nerve cells repair themselves after injury

Researchers identify patterns of mutations in early stage node negative lung adenocarcinoma

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Researchers identify a new approach for treating brain metastases associated with lung cancer

SLU researcher studies effect of bitter melon extract on treating cancer

Study of genetically modified immune cells could help improve promising treatment for melanoma

Translational Research's April issue examines progress, outlook of gene therapy research

Fralin Life Science Institute researchers use TALENS to alter mosquito genome

MU researchers redefine key regulatory process in defective protein responsible for cystic fibrosis

Dysfunction of Calcium channel in neurons of cerebellum causes different motor diseases

Findings provide structural basis for development of drugs to fight enterovirus 71 infection

Fibromyalgia: an interview with Dr Frederick Wolfe, University of Kansas School of Medicine

Using single B cell screening to boost antibody discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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