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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Sun-damaged skin responds well to laser treatment

Researchers at the University of Michigan Health System Department of Dermatology have found scientific evidence that the appearance of sun-damaged skin may be improved by treatment with a topical product that increases the skin's sensitivity to light, followed by laser therapy.

20 Oct 2008

Johns Hopkins researchers detect sweet cacophany while listening to cellular cross-talk

Johns Hopkins scientists were dubious in the early 1980s when they stumbled on small sugar molecules lurking in the centers of cells; not only were they not supposed to be there, but they certainly weren't supposed to be repeatedly attaching to and detaching from proteins, effectively switching them on and off.

20 Oct 2008

Bristol scientist puts the brakes on breast cancer

Why do breast cells grow out of control? The answer could be a step closer thanks to a grant of around £200,000 from one of the UK's leading breast cancer research charities, Breast Cancer Campaign, to University of Bristol scientist, Dr Claire Perks.

20 Oct 2008

Better TB vaccine in the pipeline

Scientists in the U.S. believe they have a vaccine in the pipeline that offers better protection from tuberculosis (TB).

20 Oct 2008

NIH funds two new centers for imaging technology for neurodegenerative disorders and software for protein analysis

The National Center for Research Resources (NCRR), a part of the National Institutes of Health (NIH), announced today it will provide up to an estimated $11 million over the next five years to create two new Biomedical Technology Research Centers (BTRCs) that will provide researchers nationwide with access to specialized research tools, training and state-of-the-art equipment.

15 Oct 2008

People with severe obstructive sleep apnea often have poor diets

A study in the October 15 issue of the Journal of Clinical Sleep Medicine shows that unrelated to obesity, people with severe SDBs consume a more unhealthy diet, which may be a factor contributing to greater cardiovascular morbidity and mortality. These findings were most evident among women.

15 Oct 2008

Shark antibodies show potential as lifesaver from cancer

Australian scientists have discovered a potentially potent weapon in the fight against cancer in antibodies taken from shark blood.

14 Oct 2008

Resveratrol shows promise for treating human alcoholic fatty liver disease

The accumulation of fat in the liver as a result of chronic alcohol consumption could be prevented by consuming resveratrol, according to a new study with mice. The research found that resveratrol reduced the amount of fat produced in the liver of mice fed alcohol and, at the same time, increased the rate at which fat within the liver is broken down.

14 Oct 2008

Design of a compound that stabilizes the main natural suppressor of tumours

An interdisciplinary team of researchers, headed by Ernest Giralt at the Institute for Research in Biomedicine (IRB Barcelona) and Javier de Mendoza at the "Institut Catala d'Investigaciió Quimica" (ICIQ, Tarragona), have discovered a substance with the capacity to maintain protein p53 stable even when it presents certain mutations that promote the appearance of cancer.

14 Oct 2008

OncoGenex achieves key regulatory milestone for lead product candidate

OncoGenex Pharmaceuticals Inc. today announced that it concluded a meeting with the U.S. Food and Drug Administration (FDA) on October 7, 2008, and that the FDA agreed that "durable pain palliation is an acceptable and desirable study endpoint" to support a product marketing approval for OGX-011 as a treatment for hormone refractory prostate cancer (HRPC).

13 Oct 2008

Unpicking the complexity of human disease

Impressive advances in our understanding of the genetic basis of disease were outlined at the 3rd ESF Functional Genomics Conference in Innsbruck, Austria.

13 Oct 2008

Study specifies chemical pathway for ions through the cell membrane

Life ultimately depends on the traffic of tiny charged particles through porous proteins studding the membrane surrounding every cell. In research published in Nature, scientists at The Rockefeller University have for the first time mapped a stepping-stone pathway of amino acids that these charged particles, or ions, follow across cell membranes.

13 Oct 2008

New maturation inhibitor drugs may help solve HIV treatment conundrum

Since AIDS was first recognized in 1981, significant advances have been made in developing an effective arsenal of drugs to manage the disease and extend patients' lives.

13 Oct 2008

Scientists image transfer of antibodies from mother's milk, to baby's gut

The transportation of antibodies from a mother to her newborn child is vital for the development of that child's nascent immune system. Those antibodies, donated by transfer across the placenta before birth or via breast milk after birth, help shape a baby's response to foreign pathogens and may influence the later occurrence of autoimmune diseases.

13 Oct 2008

Kinaxo partners with Boehringer Ingelheim

Kinaxo Biotechnologies GmbH announced today that it has entered into a two-year collaboration with Boehringer Ingelheim. Under the agreement Kinaxo will apply its new platform technologies to studies on drug mode of action and target identification. Financial details of the agreement were not disclosed.

13 Oct 2008