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Complex and messy ethical, social and cultural issues often left on table

Resolving complex ethical, social and cultural issues in the early stage of a global health research project or clinical trial can improve the impact and quality of that research, a new report says.

12 Aug 2013

Proliferation of immune cells within plaques may be potential treatment target for atherosclerosis

New insights into the development of vulnerable atherosclerotic plaques could lead to better treatment or prevention of heart attacks and strokes.

12 Aug 2013

Study of childhood epilepsies links two new genes to severe forms of disease

A genetic study of childhood epilepsies has linked two new genes to severe forms of disease and provides a novel strategy for identifying therapy targets. This study used a cutting-edge genetic technique, called exome sequencing, to search for new mutations that are not inherited.

12 Aug 2013

Children who exhibit lower conscientiousness may have adult obesity

Results from a longitudinal study show that children who exhibit lower conscientiousness (e.g., irresponsible, careless, not persevering) could experience worse overall health, including greater obesity, as adults.

12 Aug 2013

Researchers identify biomarkers of TB that may help in new treatments

Researchers at the University of Southampton have identified new markers of tuberculosis (TB) that may help in the development of new diagnostic tests and treatments.

12 Aug 2013

Celgene's pomalidomide gets approval in UK for multiple myeloma

Celgene confirmed today that Pomalidomide Celgene▼ (pomalidomide), a new oral blood cancer therapy, has been granted Marketing Authorisation by the European Medicines Agency and is now available in the UK and Ireland.

9 Aug 2013

Researchers find antibodies specific to MERS-CoV in dromedary camels

Researchers searching for signs of Middle East respiratory syndrome coronavirus in livestock animals have found antibodies specific to the new virus in dromedary camels. The research, published in The Lancet Infectious Diseases, suggests that these animals have encountered MERS-CoV, or a closely related virus, and may be one reservoir of the virus that is causing MERS in humans.

9 Aug 2013

New microfluidic chip can capture live CTCs from patient's blood

Tumor cells circulating within a patient's bloodstream can carry cancer from a primary tumor site to distant sites of the body, spreading the disease.

9 Aug 2013

Robotic intubation device automatically identifies lungs and navigates toward it

Graduates of the Hebrew University's Biodesign program revealed a robotic intubation device that automatically identifies the lungs using an infrared source and navigates toward it.

9 Aug 2013

Sericin can decrease blood glucose levels and alleviate diabetic hippocampal damage

Preliminary studies by Dr. Zhihong Chen and colleagues from Chengde Medical College have shown that sericin might improve aberrant Akt signaling, decrease heme oxygenase-1 expression in the hippocampus and cerebral cortex, and reduce the apoptosis of hippocampal neurons in diabetic rats, thus protecting the nervous system.

9 Aug 2013

Drug-related emergency department visits increase among younger adults

A new report by the Substance Abuse and Mental Health Services Administration shows that some drug-related emergency department visits increased by 300 percent -- from 5,605 visits in 2005 to 22,949 visits in 2011. These visits, made by adults aged 18 to 34, were related to the nonmedical use of central nervous system stimulants. On average, about 30 percent of these visits also involved alcohol.

9 Aug 2013

TUM scientists decode typical protein profile of tumor cells

In what is the biggest study of its kind to date, researchers from Technische Universit-t M-nchen have identified over 10,000 different proteins in cancer cells. "Nearly all anti-tumor drugs are targeted against cellular proteins," says Prof. Bernhard K-ster, Head of the TUM Chair of Proteomics and Bioanalytics. "Identifying the proteome the protein portfolio of tumor cells increases our chances of finding new targets for drugs."

9 Aug 2013

Pregnant rats fed with high-fat diet experience preeclampsia-like syndromes

Preeclampsia is a relatively common pregnancy disorder, characterized by primary hypertension and proteinuria. In patients with severe preeclampsia, eclampsia can develop, causing nervous system symptoms and signs.

9 Aug 2013

Start-up company specializes in reducing hospital readmission rates

Facing rising penalties under the health-care law for high readmission rates, some hospitals are turning to tech entrepreneurs like Chris Corio of San Francisco for help. Mr. Corio's four-year-old startup sells technology that assists patients in completing the recovery process after getting discharged.

9 Aug 2013

Study: Immune-regulating molecules can trigger lymphomas

A small group of immune-regulating molecules, when overproduced even moderately, can trigger the blood cancers known as lymphomas, according to a new study led by scientists from The Scripps Research Institute (TSRI).

9 Aug 2013

Children born by Caesarean section more vulnerable to allergies

Children who came into the world by Caesarean section are more often affected by allergies than those born in the natural way. The reason for this may be that they have a less diverse gut microbiota, according to a study by universities in Sweden and Scotland.

9 Aug 2013

Enrollment completed for Cook Medical’s study of tibiopedal access technique for treating PAD

Cook Medical has completed patient enrollment in a study evaluating a technique for achieving vascular access via below-the-knee arteries. The new access technique could be used in treating peripheral arterial disease, including patients with critical limb ischemia.

9 Aug 2013

Eisai's investigational compound receives orphan drug designation for cutaneous t-cell lymphoma

Eisai Inc. announced today that the U.S. Food and Drug Administration has granted orphan drug designation to its investigational compound (E7777) for cutaneous t-cell lymphoma. E7777 is designed to have an improved purity profile and manufacturing process.

9 Aug 2013

Investigational malaria vaccine offers protection against malaria infection in healthy adults

An investigational malaria vaccine has been found to be safe, to generate an immune system response, and to offer protection against malaria infection in healthy adults, according to the results of an early-stage clinical trial published Aug. 8 in the journal Science.

9 Aug 2013

Person with type 2 diabetes may spend nearly $85,500 to treat the disease

A person with type 2 diabetes may spend an average of nearly $85,500 to treat the disease and its complications over his or her lifetime, reports a new study in the American Journal of Preventive Medicine.

9 Aug 2013