Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Novan Therapeutics reports positive results from SB204 Phase 2 study for treatment of acne vulgaris

Novan Therapeutics, a specialty pharmaceutical company focused on advancing nitric oxide therapies for a number of diseases, announced today positive Phase 2 study results of its topical SB204 drug candidate for the treatment of acne vulgaris.

19 Mar 2014

Study provides evidence that sepsis-related mortality has steadily decreased over time

In critically ill patients in Australia and New Zealand with severe sepsis or septic shock, there was a decrease in the risk of death from 2000 to 2012, findings that were accompanied by changes in the patterns of discharge of intensive care unit (ICU) patients to home, rehabilitation, and other hospitals, according to a study appearing in JAMA.

19 Mar 2014

Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

Growing drug resistance, a high prevalence of S. aureus bacteria and ineffective antibiotics prescribed to one in three patients are among the challenges facing community hospitals in treating patients with serious bloodstream infections, according to researchers at Duke Medicine.

19 Mar 2014

Scientists build tiny "molecular drill bits" that kill bacteria by bursting through their protective cell walls

In response to drug-resistant "superbugs" that send millions of people to hospitals around the world, scientists are building tiny, "molecular drill bits" that kill bacteria by bursting through their protective cell walls.

18 Mar 2014

Sequencing reveals genetic diversity in hospital-acquired bacterium

Using genome sequencing, National Institutes of Health scientists and their colleagues have tracked the evolution of the antibiotic-resistant bacterium Klebsiella pneumoniae sequence type 258 (ST258), an important agent of hospital-acquired infections.

18 Mar 2014

AV drugs could help curb bacteria's growing resistance to antibiotic treatments

A new type of drug could help to combat growing antibiotic resistance, a study finds. Medicines that stop bacteria from harming their hosts, rather than kill them, could prevent bugs from evolving resistance to drug treatments, a review of research in the field suggests.

18 Mar 2014

New research commissioned to create infection control strategy for AMR and antibiotic usage

It is the health system’s nightmare, bubbling just below the surface of our hospitals. Infections are becoming more and more resistant to antibiotics, while secondary infection rates during hospital stays continue to rise.

18 Mar 2014

Honey helps fight antibiotic resistance, says study

Honey, that delectable condiment for breads and fruits, could be one sweet solution to the serious, ever-growing problem of bacterial resistance to antibiotics, researchers said here today.

17 Mar 2014

Longer looks: The 'making of Obamacare;' unlocking an autistic son's secrets; antibiotics and the obesity epidemic

If you walk into a farm-supply store today, you're likely to find a bag of antibiotic powder that claims to boost the growth of poultry and livestock. That's because decades of agricultural research has shown that antibiotics seem to flip a switch in young animals' bodies, helping them pack on pounds. Manufacturers brag about the miraculous effects of feeding antibiotics to chicks and nursing calves. Dusty agricultural journals attest to the ways in which the drugs can act like a kind of superfood to produce cheap meat. But what if that meat is us? (Pagan Kennedy, 3/8).

14 Mar 2014

TFDA approves TaiGen's Taigexyn NDA for treatment of community-acquired bacterial pneumonia

TaiGen Biotechnology Company, Limited today announced that the Taiwan Food and Drug Administration has approved the new drug application (NDA) of Taigexyn (nemonoxacin) oral formulation (500 mg) for the treatment of community-acquired bacterial pneumonia (CAP). With this NDA approval, Taiwan is the first region to grant marketing approval to Taigexyn.

13 Mar 2014

Aradigm reports record revenue of $4.6M in fourth quarter 2013

Aradigm Corporation (the "Company") today announced financial results for the fourth quarter and full year ended December 31, 2013.

13 Mar 2014

New research raises hopes of new class of drugs to combat antibiotic resistant infections

New research has found some compounds effective in blocking the proliferation of certain bacteria, raising hopes of a new class of drugs to combat antibiotic resistant infections

13 Mar 2014

Gut bacteria and blood cell development relationship helps immune system fight infection

The human relationship with microbial life is complicated. At almost any supermarket, you can pick up both antibacterial soap and probiotic yogurt during the same shopping trip.

13 Mar 2014

EPFL sets up foundation to release antibiotic for tuberculosis

Even though tuberculosis kills more than 1.5 million people every year, the market is not cost-effective for pharmaceutical companies. So EPFL is setting up a foundation to release an antibiotic developed in its own laboratories under EU funding.

12 Mar 2014

Research roundup: Health care and prisoners; hospitalized patients' surrogates; suicides in the army

As a group, jail-involved individuals, which we define here as people with a history of arrest and jail admission in the recent past, carry a heavy illness burden, with high rates of infectious and chronic disease as well as mental illness and substance use.

10 Mar 2014

Researchers find that protein synthesis can be studied in adult stem cells

For the first time, researchers have shown that an essential biological process known as protein synthesis can be studied in adult stem cells - something scientists have long struggled to accomplish. The groundbreaking findings from the Children's Medical Center Research Institute at UT Southwestern (CRI) also demonstrate that the precise amount of protein produced by blood-forming stem cells is crucial to their function.

10 Mar 2014

Scientists uncover bacterial secretion system that allows sharing of genetic material between bacteria

The system that allows the sharing of genetic material between bacteria - and therefore the spread of antibiotic resistance - has been uncovered by a team of scientists at Birkbeck, University of London and UCL.

10 Mar 2014

Study: Severe C. difficile infections occur among children who prescribed antibiotics in doctor's offices

The majority of pediatric Clostridium difficile infections, which are bacterial infections that cause severe diarrhea and are potentially life-threatening, occur among children in the general community who recently took antibiotics prescribed in doctor's offices for other conditions, according to a new study by the Centers for Disease Control and Prevention published this week in Pediatrics.

10 Mar 2014

Food safety measures taken by hospital minimize risk to food handlers

A new study found more than 80 percent of raw chicken used in hospitals in food for patients and staff was contaminated with a form of antibiotic resistant bacteria called extended-spectrum beta-lactamase (ESBL) producing E. coli. While sufficient preparation eliminated the presence of bacteria, poultry meat delivered to hospital kitchens remains a potential point of entry for these dangerous bacteria into the hospital.

10 Mar 2014

Scientists use novel metagenomic approaches to characterize microbial communities that reside in human gut

The gut microbiota contains a vast number of microorganisms from all three domains of life, including bacteria, archaea and fungi, as well as viruses. These interact in a complex way to contribute towards both health and the development of disease - interactions that are only now being elucidated thanks to the application of advanced DNA sequencing technology in this field.

10 Mar 2014

Antibiotic News and Research

Further Reading

Novan Therapeutics reports positive results from SB204 Phase 2 study for treatment of acne vulgaris

Study provides evidence that sepsis-related mortality has steadily decreased over time

Many community hospitals prescribe ineffective antibiotics for patients with bloodstream infections

Scientists build tiny "molecular drill bits" that kill bacteria by bursting through their protective cell walls

Sequencing reveals genetic diversity in hospital-acquired bacterium

AV drugs could help curb bacteria's growing resistance to antibiotic treatments

New research commissioned to create infection control strategy for AMR and antibiotic usage

Honey helps fight antibiotic resistance, says study

Longer looks: The 'making of Obamacare;' unlocking an autistic son's secrets; antibiotics and the obesity epidemic

TFDA approves TaiGen's Taigexyn NDA for treatment of community-acquired bacterial pneumonia

Aradigm reports record revenue of $4.6M in fourth quarter 2013

New research raises hopes of new class of drugs to combat antibiotic resistant infections

Gut bacteria and blood cell development relationship helps immune system fight infection

EPFL sets up foundation to release antibiotic for tuberculosis

Research roundup: Health care and prisoners; hospitalized patients' surrogates; suicides in the army

Researchers find that protein synthesis can be studied in adult stem cells

Scientists uncover bacterial secretion system that allows sharing of genetic material between bacteria

Study: Severe C. difficile infections occur among children who prescribed antibiotics in doctor's offices

Food safety measures taken by hospital minimize risk to food handlers

Scientists use novel metagenomic approaches to characterize microbial communities that reside in human gut

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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