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New guidelines on the management of antithrombotic agents for endoscopic procedures published

According to a new guideline from the American Society for Gastrointestinal Endoscopy (ASGE) regarding the management of antithrombotic agents for endoscopy, aspirin and/or NSAIDs may be continued for all elective endoscopic procedures.

9 Dec 2009

Mozobil with chemotherapy may have a therapeutic impact on leukemic cells, reveals study

Genzyme Corporation announced today that a Phase 1/2 trial provided early clinical data suggesting that Mozobil (plerixafor injection) in combination with chemotherapy may offer a therapeutic impact on leukemic cells protected in bone marrow.

9 Dec 2009

Antithrombotic medication may increase risk of bleeding in dialysis patients undergoing PCI procedure

Approximately 20 percent of dialysis patients undergoing a percutaneous coronary intervention (PCI; procedure such as angioplasty) are given an antithrombotic medication they should not receive, which may increase their risk for in-hospital bleeding, according to a study in the December 9 issue of JAMA.

9 Dec 2009

Tips to prevent hangover during holiday season

"Eating food is an important element in reducing drinking and reducing risk of intoxication," Garbutt said. Eat a meal before you take your first sip of alcohol, he advises, and continue to take in food as the night wears on. Food, fats especially, help slow down the body's absorption of alcohol. But to truly be effective, the food must be in your stomach first. If you wait until you're feeling buzzed or tipsy to start eating, it's already too late.

9 Dec 2009

Texas Sinus Center offers FinESS Sinus Treatment to break the cycle of chronic sinusitis

Dr. James Atkins, founder of the Texas Sinus Center (www.texassinuscenter.com), today announced he is now offering the FinESS® Sinus Treatment, a minimally invasive treatment that breaks the cycle of chronic sinusitis (CRS) at Foundation Surgical Hospital of San Antonio.

8 Dec 2009

Defibrotide drug effective against hepatic veno-occlusive disease

Defibrotide, a novel drug which modulates the response of blood vessels to injury, was markedly more effective than standard treatment in post-stem cell transplant patients with hepatic veno-occlusive disease, a life threatening toxicity of transplant caused by blockages in tiny blood vessels of the liver, according to a study led by Dana-Farber Cancer Institute scientists.

8 Dec 2009

Amgen announces results from first Phase 1/2 study of Nplate

Amgen Inc. today announced results from its first Phase 1/2 study evaluating the safety and efficacy of Nplate® (romiplostim) in children with chronic immune thrombocytopenic purpura (ITP).

8 Dec 2009

Masimo SpHb monitoring technology installed at Brookdale University Hospital and Medical Center

Masimo, the inventor of Pulse CO-Oximetry(TM) and Measure-Through Motion and Low Perfusion pulse oximetry, announced today that Brookdale University Hospital and Medical Center in Brooklyn, New York, has completed its system-wide conversion to Masimo SET pulse oximetry technology.

7 Dec 2009

Atrium Medical commences enrollment in its INFUSE AMI trial

Atrium Medical Corporation announced that the 1st patient was enrolled in the INFUSE AMI trial. INFUSE AMI is a multi-center, multi-national, prospective, randomized, single blind trial examining how patients with heart attacks are treated. The study's aim is to help determine the best way to treat patients with an acute anterior wall myocardial infarction (acute MI) with ST segment elevation, commonly referred to as STEMIs.

7 Dec 2009

Dabigatran etexilate prevents recurrent VTE with less bleeding than warfarin

Boehringer Ingelheim today announced very positive results from their landmark RE-COVER™ study – the most advanced trial programme assessing a novel oral anticoagulant in development for acute venous thromboemolism (VTE) treatment – presented at the American Society of Hematology Annual Meeting1 and published in the New England Journal of Medicine online.

7 Dec 2009

New oral drug is safe and effective to combat clotting disorder

A new study provides welcome news for patients with a common clotting disorder known as venous thromboembolism (VTE).

7 Dec 2009

J&JPRD announces clinical results of new oral anticoagulant therapy for venous thromboembolism

Johnson & Johnson Pharmaceutical Research and Development, L.L.C. (J&JPRD), announced today that results from the Phase III EINSTEIN-Extension (EXT) clinical trial of the novel oral anticoagulant rivaroxaban showed a significant reduction in the risk of recurrent symptomatic venous thromboembolism (VTE), compared to placebo, in patients who have been treated for a previous deep vein thrombosis (DVT) or pulmonary embolism (PE).

7 Dec 2009

Anticoagulants used to prevent clots in placental blood vessels ineffective, reveals research

Blood clotting, or coagulation, is an important process that prevents excessive bleeding when a blood vessel is injured. Sometimes, however, clots form on the inside of vessels without an obvious injury or do not dissolve naturally, a potentially life-threatening situation requiring treatment.

7 Dec 2009

Amgen announces results from three studies on the safety and efficacy of Nplate

Amgen Inc. today announced results from three studies on the safety and efficacy of Nplate® (romiplostim) in adult patients with myelodysplastic syndromes (MDS).

7 Dec 2009

Dabigatran etexilate offers effective therapy to prevent recurrent VTE

Results from the landmark RE-COVER(TM) study were presented today at the American Society of Hematology Annual Meeting and published online in the New England Journal of Medicine.

6 Dec 2009

ISIS-FXIRx and ISIS-SMNRx included in Isis Pharmaceuticals' development pipeline

Isis Pharmaceuticals, Inc. announced today that it has added two new drugs to its development pipeline, ISIS-FXIRx and ISIS-SMNRx.

4 Dec 2009

Enrollment closed early in Cubist Pharmaceuticals' ecallantide Phase 2 program

Cubist Pharmaceuticals, Inc. today announced the early closing of enrollment in its ecallantide Phase 2 program. Ecallantide, in development as therapy to reduce bleeding in on-pump cardiac surgery, is now known as CB-500,929. After a regularly scheduled review meeting, the Data Safety Monitoring Board (DSMB) contacted the company to recommend a temporary suspension in enrollment in one of the CB-500,929 trials, CONSERV-2.

3 Dec 2009

Bleeding News and Research

New guidelines on the management of antithrombotic agents for endoscopic procedures published

Mozobil with chemotherapy may have a therapeutic impact on leukemic cells, reveals study

Antithrombotic medication may increase risk of bleeding in dialysis patients undergoing PCI procedure

Tips to prevent hangover during holiday season

Texas Sinus Center offers FinESS Sinus Treatment to break the cycle of chronic sinusitis

Defibrotide drug effective against hepatic veno-occlusive disease

Amgen announces results from first Phase 1/2 study of Nplate

Masimo SpHb monitoring technology installed at Brookdale University Hospital and Medical Center

Atrium Medical commences enrollment in its INFUSE AMI trial

Dabigatran etexilate prevents recurrent VTE with less bleeding than warfarin

New oral drug is safe and effective to combat clotting disorder

J&JPRD announces clinical results of new oral anticoagulant therapy for venous thromboembolism

Anticoagulants used to prevent clots in placental blood vessels ineffective, reveals research

Amgen announces results from three studies on the safety and efficacy of Nplate

Dabigatran etexilate offers effective therapy to prevent recurrent VTE

ISIS-FXIRx and ISIS-SMNRx included in Isis Pharmaceuticals' development pipeline

Enrollment closed early in Cubist Pharmaceuticals' ecallantide Phase 2 program

Wyeth pledges more than 40 million IUs of factor concentrates to WFH

Earlier diagnosis of cancer saves 5,000 to 10,000 lives each year, says Professor Mike Richards

NHLBI awards stimulus funds for hemophilia drug research

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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