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Olive oil's secret weapon against Alzheimer's: phenolic compounds

A comprehensive review in the International Journal of Molecular Sciences highlights the potential of extra-virgin olive oil and its phenolic compounds in preventing and treating Alzheimer's disease through various mechanisms, including reducing amyloid-beta accumulation and neuroinflammation.

12 Feb 2024

Novel approach improves CAR T-cell therapy efficacy against acute myeloid leukemia

St. Jude Children's Research Hospital scientists improved chimeric antigen receptor (CAR) T–cell immunotherapy for acute myeloid leukemia (AML), demonstrating better efficacy in the lab.

12 Feb 2024

Study reveals role of protein modification in neurodegenerative disease progression

Neurodegenerative diseases, such as Alzheimer's and Parkinson's, present a significant health challenge, affecting over 50 million people globally.

12 Feb 2024

Complications during pregnancy linked to higher risk of heart disease and stroke later in life

Heart disease is the leading cause of death among women, and women who have complications during pregnancy, such as high blood pressure or gestational diabetes, have a significantly higher risk of heart disease and stroke later in life, according to a new scientific statement from the American Heart Association, published today in Circulation, the Association's flagship peer-reviewed journal.

12 Feb 2024

Promising new CMV vaccine shows stronger immune response

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

12 Feb 2024

Study reveals a crucial survival tactic employed by cancer cells

A study led by the group of Didier Trono at EPFL has revealed a crucial survival tactic employed by cancer cells.

12 Feb 2024

Study may open up new ways of approaching metabolic diseases

A study led by the University of Barcelona and the Biomedical Research Networking Center in Diabetes and Associated Metabolic Disorders (CIBERDEM) reveals how a new mechanism could improve the efficiency of currently available treatments for diabetes.

12 Feb 2024

Groundbreaking study shows monocytes migrate to brain's emotional centers during stress

Researchers report a mechanism wherein peripheral immune factors could impact central nervous system (CNS) function and behavior under stress.

12 Feb 2024

CRISPR could be used for faster monkeypox testing

Mpox, formerly known as monkeypox, is a rare viral disease that is spread through physical contact between people.

12 Feb 2024

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Humans are still evolving, and Tatum Simonson, PhD, founder and co-director of the Center for Physiological Genomics of Low Oxygen at University of California School of Medicine, plans to use evolution to improve healthcare for all.

12 Feb 2024

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4) expression.

12 Feb 2024

Drug repurposing study finds lonafarnib effective against RSV

A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

11 Feb 2024

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) – the biggest genetic risk factor for late-onset Alzheimer's disease.

9 Feb 2024

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis."

9 Feb 2024

UH Brain Health & Memory Center now treating patients with FDA-approved drug for Alzheimer's disease

University Hospitals (UH) Brain Health & Memory Center is now treating patients with LEQEMBI (lecanemab), a Food and Drug Administration-approved medication for the treatment of Alzheimer's disease.

9 Feb 2024

Understanding the virological properties of SARS-CoV-2 variant JN.1

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a worldwide threat.

9 Feb 2024

Scientists develop safer CAR T-cell strategy for treating lymphomas

In the treatment of aggressive lymphomas and blood cancer (leukaemia), so-called chimeric antigen receptor T cells (CAR T cells) are increasingly being used.

9 Feb 2024

Breakthrough technique unveils secrets of "backtracking" in gene regulation

A technique can determine for the first time how frequently, and exactly where, a molecular event called "backtracking" occurs throughout the genetic material (genome) of any species, a new study shows.

9 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

AI tool maps protein function in tumors, paving way for personalized cancer treatment

Scientists have developed a new AI tool that maps the function of proteins in a cancerous tumor, enabling clinicians to decide how to target treatment in a more precise way.

9 Feb 2024

Protein C News and Research

Olive oil's secret weapon against Alzheimer's: phenolic compounds

Novel approach improves CAR T-cell therapy efficacy against acute myeloid leukemia

Study reveals role of protein modification in neurodegenerative disease progression

Complications during pregnancy linked to higher risk of heart disease and stroke later in life

Promising new CMV vaccine shows stronger immune response

Study reveals a crucial survival tactic employed by cancer cells

Study may open up new ways of approaching metabolic diseases

Groundbreaking study shows monocytes migrate to brain's emotional centers during stress

CRISPR could be used for faster monkeypox testing

Understanding how natural genetic variation contributes to adaptive responses to low oxygen

Androgen receptor signaling found to upregulate gene driving melanoma severity in men

Drug repurposing study finds lonafarnib effective against RSV

Unlocking Alzheimer's secrets: Study pinpoints APOE4's harmful effect on lipids

Blood biomarkers in TGF-β pathway identify hidden liver cancer risk

UH Brain Health & Memory Center now treating patients with FDA-approved drug for Alzheimer's disease

Understanding the virological properties of SARS-CoV-2 variant JN.1

Scientists develop safer CAR T-cell strategy for treating lymphomas

Breakthrough technique unveils secrets of "backtracking" in gene regulation

Rucaparib and its major metabolite exhibit differential biological activity and synergy

AI tool maps protein function in tumors, paving way for personalized cancer treatment

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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