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Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus.

2 Mar 2013

Study shows triple-negative breast cancer cells missing key enzyme

A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain - providing insight into potential therapeutic targets to treat the aggressive cancer.

2 Mar 2013

Mercury exposure raises diabetes risk later in life

People with a high level of mercury exposure in young adulthood are at an increased risk for developing diabetes later in life, report researchers.

1 Mar 2013

Kallikrein gene variants modulate OSCC development

Polymorphisms in the kallikrein7 and kallikrein10 genes are associated with the development and progression of oral squamous cell carcinoma, a study in Taiwanese men indicates.

1 Mar 2013

Eye-rubbing may provoke, aggravate keratoconus

Rubbing the eyes leads to an increase in protease activity and levels of protease and inflammatory mediators, a clinical study shows.

1 Mar 2013

First Edition: March 1, 2013

Kaiser Health News staff writer Mary Agnes Carey reports: "David P. Blom is one of thousands of hospital executives across the country who are bracing for a reduction in Medicare payments as part of a series of federal spending cuts that begin Friday. Blom, 58, is president and chief executive officer of OhioHealth, a Columbus, Ohio, based not-for-profit health care system that includes 18 hospitals, 23 health and surgery centers, home-health providers and other facilities."

1 Mar 2013

Researchers elucidate how Fgf8 is controlled by multiple regulatory elements in mammal embryos

During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in this process, controlling in particular the growth of the limbs and the formation of the different regions of the brain. Researchers at EMBL have elucidated how Fgf8 in mammal embryos is, itself, controlled by a series of multiple, interdependent regulatory elements.

1 Mar 2013

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for under-served medical needs in neurology and cardiology, announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).

1 Mar 2013

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Promethera Biosciences, a Belgian biotechnology company developing Promethera(R) HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announced that it has successfully treated a patient with liver progenitor cells enrolled in its Phase I/II trial.

1 Mar 2013

New way to identify heterogeneous brain cells by looking at epigenetic variation

Scientists from the Johns Hopkins University School of Medicine in Baltimore, MD have developed a new way to identify heterogeneous brain cells by looking at epigenetic variation (the heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence).

1 Mar 2013

Not all acne bacteria trigger pimples: Study

The bacteria that cause acne live on everyone's skin, yet one in five people is lucky enough to develop only an occasional pimple over a lifetime.

1 Mar 2013

UMDNJ biochemist to research into mechanisms that control gene expression in mitochondria

Dmitry Temiakov, PhD, a biochemist at the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, has received a five-year, $1.5 million grant from the National Institutes of Health (NIH) to fund research into the molecular mechanisms that control gene expression in mitochondria, the organelles that are the "power plants" of cellular activity.

1 Mar 2013

Study identifies neural pathways tied to eating for pleasure

New research from the University of Georgia has identified the neural pathways in an insect brain tied to eating for pleasure, a discovery that sheds light on mirror impulsive eating pathways in the human brain.

1 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Brown University develops new implantable and rechargeable wireless brain sensor

A team of neuroengineers based at Brown University has developed a fully implantable and rechargeable wireless brain sensor capable of relaying real-time broadband signals from up to 100 neurons in freely moving subjects.

28 Feb 2013

TikoMed, BRI partner to investigate IBsolvMIR in phase II trial for chronic pancreatitis

Baylor Research Institute (BRI), the research arm of Baylor Health Care System, and TikoMed AB announced today that an agreement has been established to investigate TikoMed´s product IBsolvMIR® in a phase II clinical trial.

28 Feb 2013

Viewpoints: Michelle Obama makes a business case for healthy food; Orszag weighs reforms to Medical malpractice

For years, America's childhood obesity crisis was viewed as an insurmountable problem, one that was too complicated and too entrenched to ever really solve. According to the conventional wisdom, healthy food simply didn't sell - the demand wasn't there and higher profits were found elsewhere - so it just wasn't worth the investment. But thanks to businesses across the country, today we are proving the conventional wisdom wrong.

28 Feb 2013

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

New research published today in the Biochemical Journal describes the discovery of a new cancer target.

28 Feb 2013

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Hailed as a major step forward in the effort to develop targeted cancer therapies, a recently approved drug for the most common type of skin cancer has been a mixed blessing for patients. Although the initial response is usually dramatic, the tumors often recur as the cancer becomes resistant to treatment.

28 Feb 2013

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.

28 Feb 2013

B Cell News and Research

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Study shows triple-negative breast cancer cells missing key enzyme

Mercury exposure raises diabetes risk later in life

Kallikrein gene variants modulate OSCC development

Eye-rubbing may provoke, aggravate keratoconus

First Edition: March 1, 2013

Researchers elucidate how Fgf8 is controlled by multiple regulatory elements in mammal embryos

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

New way to identify heterogeneous brain cells by looking at epigenetic variation

Not all acne bacteria trigger pimples: Study

UMDNJ biochemist to research into mechanisms that control gene expression in mitochondria

Study identifies neural pathways tied to eating for pleasure

Stem cell line could also advance research into liver cancers, cystic fibrosis

Brown University develops new implantable and rechargeable wireless brain sensor

TikoMed, BRI partner to investigate IBsolvMIR in phase II trial for chronic pancreatitis

Viewpoints: Michelle Obama makes a business case for healthy food; Orszag weighs reforms to Medical malpractice

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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