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Uric acid holds potential for central nervous system damage

Uric acid is commonly associated with the excruciatingly painful joint disease known as gout, but it can also play a crucial role in the treatment of spinal cord injury and other central nervous system disorders, such as stroke, multiple sclerosis and Parkinson's disease, according to Rutgers' Bonnie Firestein.

3 Jan 2007

A central thermogenic-like mechanism in feeding regulation

During periods of fasting, brain cells responsible for stimulating the appetite make sure that you stay hungry.

2 Jan 2007

Stem cells grown into brain cells on a new 3D scaffold of tiny protein fragments

An MIT engineer and Italian colleagues will report the invention-which may one day replace the ubiquitous Petri dish for growing cells-in PLoS ONE.

2 Jan 2007

Research offers hope for alcoholics

Scientists at Melbourne's Howard Florey Institute have discovered a system in the brain that stops an alcoholic's craving for alcohol, as well as prevent relapse once they have recovered from alcohol addiction.

12 Dec 2006

Human embryonic stem cells show potential in treating rats with Parkinson's symptoms

Brain cells derived from human embryonic stem cells improved the condition of rats with Parkinson's-like symptoms dramatically, but the treatment caused a significant problem - the appearance of brain tumors - that scientists are now working to solve.

2 Dec 2006

Researchers discover protein interaction that may explain how Huntington's disease affects the brain

The findings, published in and featured on the cover of the current issue of Human Molecular Genetics, show how the mutated Huntington's protein interacts with another protein to cause dramatic accumulation of cholesterol in the brain.

2 Dec 2006

Ecstasy harmful to the brain even in small doses

Dutch researchers have found that even a small amount of ecstasy can be harmful to the brain.

29 Nov 2006

Researchers use gene therapy to reduce the development of epileptic seizures

For the first time, researchers have inhibited the development of epilepsy after a brain insult in animals. By using gene therapy to modify signaling pathways in the brain, neurology researchers found that they could significantly reduce the development of epileptic seizures in rats.

8 Nov 2006

Research sheds light on episodic memory

Memories of events comprise many components--including sights, sounds, smells, and tastes. Somehow the many features of an episodic memory are woven together into a coherent whole, and researchers have had little understanding of how this binding takes place as the memories are processed by the brain's memory center, the hippocampus.

8 Nov 2006

Scientists spot mechanism behind promising new sleep drug

An experimental drug called gaboxadol may soon help millions of bleary-eyed insomniacs get to sleep, and a multi-center team of U.S. scientists believes they've pinpointed just how the drug works.

1 Nov 2006

Potential for first diagnostic DNA test to guide antidepressant treatment

Treatment of depression is difficult for both patients and for psychiatrists. While there are numerous drugs available that work, finding the right one -- or right combination -- is, at times, a matter of trial and error.

31 Oct 2006

Effective test for screening Huntington's disease drugs

A test using cultured cells provides an effective way to screen drugs against Huntington's disease and shows that two compounds - memantine and riluzole - are most effective at keeping cells alive under conditions that mimic the disorder, UT Southwestern Medical Center researchers report.

30 Oct 2006

Implantable chip to establish new nerve connections in brain area that controls movement

Researchers at the University of Washington (UW) are working on an implantable electronic chip that may help establish new nerve connections in the part of the brain that controls movement.

24 Oct 2006

Researchers identify peptide that spurs cargo transport in nerve cells

For the first time, researchers have identified a peptide that can spur cargo transport in nerve cells, a discovery that could help scientists better understand nerve cell function and test possible therapies for neurodegenerative diseases.

24 Oct 2006

Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse

By studying a gene earlier linked to deafness in humans, researchers now have new insight into the molecular process by which components of the inner ear send messages to the brain.

20 Oct 2006

PGC-1 alpha implicated in Huntington's disease neurodegeneration

A metabolic disorder underlies the brain effects found in those with Huntington's disease, researchers report in an advance article publishing online October 19, 2006. The article will appear in the November 2006 issue of the journal Cell Metabolism, published by Cell Press.

20 Oct 2006

New Purdue biochip may speed drug development

Purdue University researchers have developed a biochip that measures the electrical activities of cells and is capable of obtaining 60 times more data in just one reading than is possible with current technology.

20 Oct 2006

Parkinson's disease affects more than just motor control

Although Parkinson's disease is most commonly viewed as a "movement disorder," scientists have found that the disease also causes widespread abnormalities in touch and vision - effects that have now been verified using functional magnetic resonance imaging (fMRI) of the brain.

17 Oct 2006

Researchers identifiy how immune system contributes to nerve fiber damage caused by multiple sclerosis

Researchers have identified how the body's own immune system contributes to the nerve fiber damage caused by multiple sclerosis, a finding that can potentially aid earlier diagnosis and improved treatment for this chronic disease.

16 Oct 2006