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New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Among younger patients newly diagnosed with chronic lymphocytic leukemia (CLL), treatment with a combination of chemotherapy and a molecularly targeted drug significantly improves response over what is typically seen with chemotherapy alone, according to an investigator-initiated multi-center phase II clinical trial.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

PARP inhibitor can be new treatment option for patients with metastatic breast cancer, BRCA mutations

In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended progression-free survival (PFS) and improved quality-of-life measures over available chemotherapies for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

8 Dec 2017

University of Adelaide receives $23.2 million for preterm birth research

The University of Adelaide has been awarded $23.2 million for new research tackling some of the world's most significant health problems, including one of the biggest killers of children: preterm birth.

8 Dec 2017

Bacteria may be involved in progression of cancers in the mouth, study suggests

Scientists at the School of Dental Science in Trinity have made an important discovery involving bacteria and a pre-cancerous growth called oral leukoplakia which can precede oral cancer.

7 Dec 2017

Statisticians estimate modern contraceptive prevalence in world’s poorest nations

Statisticians Leontine Alkema, Niamh Cahill and Chuchu Wei at the University of Massachusetts Amherst, with others, today released new estimates and projections of modern contraceptive prevalence and other family planning outcomes for the 69 poorest countries of the world.

5 Dec 2017

Study uncovers genes that drive peanut allergy reactions

Mount Sinai researchers have identified six genes that activate hundreds of other genes in children experiencing severe allergic reactions to peanuts.

5 Dec 2017

Penn study: New dental material kills bacteria and resists biofilm growth

Dentists rely on composite materials to perform restorative procedures, such as filling cavities. Yet these materials, like tooth enamel, can be vulnerable to the growth of plaque, the sticky biofilm that leads to tooth decay.

5 Dec 2017

Researchers identify oral bacteria linked to esophageal cancer

Researchers at NYU Langone Health's Perlmutter Cancer Center report that at least three kinds of bacteria in the mouths of Americans may heighten or lower their risk of developing esophageal cancer.

1 Dec 2017

Oral bacteria that lead to periodontal disease linked to higher risk of esophageal cancer

An analysis of bacteria present in the mouth showed that some types of bacteria that lead to periodontal disease were associated with higher risk of esophageal cancer.

1 Dec 2017

AIDA project optimizes use of old antibiotics for better patient care

A European consortium of researchers studied five off-patent community and hospital antibiotics with modern methods. They integrated the results of three randomised controlled clinical trials with extensive non-clinical studies.

29 Nov 2017

Elevated oral pathogens, less bacterial diversity linked to risk of developing precancerous gastric lesions

Elevated pathogen colonization and a lack of bacterial diversity in the mouth were identified in people with precancerous lesions that could precede stomach cancer, finds a new study led by New York University College of Dentistry and New York University School of Medicine.

28 Nov 2017

Capsule research could transform treatment for C. difficile infections

An Alberta-led clinical trial has shown Fecal Microbiota Transplant (FMT) is as effective in treating clostridium difficile (C. difficile) infections whether delivered by colonoscopy or by swallowing capsules.

28 Nov 2017

New cancer drug begins clinical trial in human patients with rare brain tumor

A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the brain.

28 Nov 2017

Study highlights overlooked impact of sugar-sweetened beverages on oral health

The latest Australian research to look at sugar-sweetened beverage consumption reveals one in seven adolescents is drinking more than two cups a day, and is two to three times more likely to have oral health problems than those who do not drink sweetened beverages.

27 Nov 2017

Novel discovery connects innate immunity deficiencies to rampant caries in some children

Researchers at Umeå University in Sweden have made a novel discovery connecting genetic innate immunity deficiencies to rampant caries and increased risk of dental caries affecting about one in five children.

27 Nov 2017

Postmenopausal hormone therapy not linked to increased risk of stroke

Postmenopausal hormone therapy is not associated with increased risk of stroke, provided that it is started early, according to a report from Karolinska Institutet in Sweden published in the journal PLOS Medicine.

23 Nov 2017

Study: Cancer patients willing to swap drug efficacy for reduced risk of adverse events

When choosing their preferred treatment, people with chronic lymphocytic leukemia (CLL) place the highest value on medicines that deliver the longest progression-free survival, but are willing to swap some drug efficacy for a reduced risk of serious adverse events according to a study published online in Blood Advances, a Journal of the American Society of Hematology.

22 Nov 2017

Young people in Britain becoming more sexually adventurous

New research has shown that young heterosexual couples in United Kingdom are trying out a wide range of different sexual practices including anal sex with their partners of the opposite sex.

20 Nov 2017

Oral News and Research

New, more easily administered therapies offer benefits for bleeding and clotting disorders

Combination of chemotherapy and targeted drug improves response in younger CLL patients

Two immunotherapy approaches for multiple myeloma show hope

PARP inhibitor can be new treatment option for patients with metastatic breast cancer, BRCA mutations

University of Adelaide receives $23.2 million for preterm birth research

Bacteria may be involved in progression of cancers in the mouth, study suggests

Statisticians estimate modern contraceptive prevalence in world’s poorest nations

Study uncovers genes that drive peanut allergy reactions

Penn study: New dental material kills bacteria and resists biofilm growth

Researchers identify oral bacteria linked to esophageal cancer

Oral bacteria that lead to periodontal disease linked to higher risk of esophageal cancer

AIDA project optimizes use of old antibiotics for better patient care

Elevated oral pathogens, less bacterial diversity linked to risk of developing precancerous gastric lesions

Capsule research could transform treatment for C. difficile infections

New cancer drug begins clinical trial in human patients with rare brain tumor

Study highlights overlooked impact of sugar-sweetened beverages on oral health

Novel discovery connects innate immunity deficiencies to rampant caries in some children

Postmenopausal hormone therapy not linked to increased risk of stroke

Study: Cancer patients willing to swap drug efficacy for reduced risk of adverse events

Young people in Britain becoming more sexually adventurous

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