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Village doctor-led telemedicine reduces cardiovascular events in rural China

Telemedicine support to village doctors could hold the key to improving access to care for China's rural elderly at risk for developing potentially life-threatening complications resulting from untreated atrial fibrillation, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug - 2 Sept).

2 Sep 2024

Invasive strategy shows no benefit in cardiovascular death reduction for older NSTEMI patients

An invasive strategy vs. optimal medical therapy alone after a non-ST-elevation myocardial infarction (NSTEMI) in older adults did not affect the combined risk of cardiovascular death or MI, although non-fatal MIs and subsequent revascularisation procedures were reduced, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

Melbourne researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for children with leukemia and bone marrow failure disorders.

2 Sep 2024

New method revolutionizes DNA-encoded chemical libraries

Nowadays, there's lots of buzz about spectacular new medical treatments such as personalised cancer therapy with modified immune cells or antibodies.

2 Sep 2024

$Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction$

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, according to an international clinical trial led by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system.

2 Sep 2024

Edoxaban monotherapy superior to dual therapy in patients with high-risk AF and stable CAD

Edoxaban monotherapy reduced net adverse clinical events compared with edoxaban plus a single antiplatelet agent, when used as long-term antithrombotic therapy, in patients with high-risk atrial fibrillation (AF) and stable coronary artery disease (CAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

OCEANIC-AF trial reveals inferiority of asundexian to apixaban for stroke prevention

Asundexian 50 mg daily was inferior to apixaban for stroke and systemic embolism prevention in high-risk patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

New study confirms safety of SGLT2 inhibitors after acute myocardial infarction

The SGLT2 inhibitor empagliflozin confers kidney-protective benefits and can therefore be given safely and effectively to patients when they are hospitalized for acute myocardial infarction (MI), a Mount Sinai-led global team of researchers has shown.

1 Sep 2024

Study links blood markers to long-term cardiovascular risk in women

Research supported by the National Institutes of Health has found that measuring two types of fat in the bloodstream along with C-reactive protein (CRP), a marker of inflammation, can predict a woman's risk for cardiovascular disease decades later.

1 Sep 2024

Triple-pill combination GMRx2 outperforms standard care in lowering blood pressure

New research shows that a treatment plan based on novel combination of low doses of three anti-hypertensive drugs in a single pill - known as GMRx2 - was superior to a high-quality standard care treatment plan at lowering blood pressure in patients with uncontrolled hypertension.

1 Sep 2024

QUADRO trial demonstrates superior blood pressure control with four-in-one medication

A single-pill combination of four blood-pressure (BP)-lowering medications was significantly more effective than a combination of three medications, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

RESHAPE-HF2 trial shows M-TEER as effective treatment for functional mitral regurgitation

Mitral transcatheter edge-to-edge repair (M-TEER) reduced cardiovascular death and heart failure (HF)-related hospitalizations with improved health status in patients with HF and moderate to severe functional mitral regurgitation (FMR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Low-dose triple-pill combination outperforms standard care for blood pressure control in Nigerian adults

A low-dose triple single-pill combination-based protocol achieved better blood pressure (BP) control than a standard-care protocol in Black African Nigerian adults with uncontrolled hypertension, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

MATTERHORN trial finds TEER non-inferior to surgery for secondary mitral regurgitation

There was no difference in efficacy between transcatheter edge-to-edge repair (TEER) and surgery in patients with secondary mitral regurgitation (MR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

T-TEER shows promising outcomes in severe tricuspid regurgitation patients after one year

Tricuspid transcatheter edge-to-edge repair (T-TEER) significantly reduced the severity of secondary tricuspid regurgitation and improved quality of life after 1 year, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Research suggests flexible approach to antiplatelet management after drug-eluting stent implantation

Among patients undergoing non-cardiac surgery more than 1 year after coronary drug-eluting stent (DES) implantation, there was no difference with respect to ischaemic outcomes or major bleeding between perioperative aspirin monotherapy and receiving no antiplatelet therapy, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TAVI outperforms surgery in reducing complications for women with severe aortic stenosis

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Study finds no added benefit to routine potassium supplementation after CABG

For the prevention of new-onset atrial fibrillation (AF) after isolated coronary artery bypass graft (CABG) surgery, giving potassium supplements only when levels dropped below the lower limit of normal was non-inferior to routinely supplementing potassium to the upper limit of normal, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

New imaging technology enhances detection of tumor remnants

The imaging techniques currently used in biological research cannot penetrate into deeper tissue layers.

30 Aug 2024

Advancing precision medicine with functional information in cancer treatment

A new editorial was published in Volume 11 of Oncoscience on July 19, 2024, entitled, "Functional information offers individualized adaptive cancer therapies."

30 Aug 2024

Therapy News and Research

Village doctor-led telemedicine reduces cardiovascular events in rural China

Invasive strategy shows no benefit in cardiovascular death reduction for older NSTEMI patients

Breakthrough in blood stem cell development offers hope for leukemia and bone marrow failure

New method revolutionizes DNA-encoded chemical libraries

Finerenone shows promise for heart failure with mildly reduced or preserved ejection fraction

Edoxaban monotherapy superior to dual therapy in patients with high-risk AF and stable CAD

OCEANIC-AF trial reveals inferiority of asundexian to apixaban for stroke prevention

New study confirms safety of SGLT2 inhibitors after acute myocardial infarction

Study links blood markers to long-term cardiovascular risk in women

Triple-pill combination GMRx2 outperforms standard care in lowering blood pressure

QUADRO trial demonstrates superior blood pressure control with four-in-one medication

RESHAPE-HF2 trial shows M-TEER as effective treatment for functional mitral regurgitation

Low-dose triple-pill combination outperforms standard care for blood pressure control in Nigerian adults

MATTERHORN trial finds TEER non-inferior to surgery for secondary mitral regurgitation

T-TEER shows promising outcomes in severe tricuspid regurgitation patients after one year

Research suggests flexible approach to antiplatelet management after drug-eluting stent implantation

TAVI outperforms surgery in reducing complications for women with severe aortic stenosis

Study finds no added benefit to routine potassium supplementation after CABG

New imaging technology enhances detection of tumor remnants

Advancing precision medicine with functional information in cancer treatment

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