Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Newly discovered ERK pathway proteins related to CagA induced disease

Cytotoxin-associated gene A protein (CagA) from type I H.pylori has been proved by epidemiological and experimental studies to be closely associated with the H.pylori induced gastric diseases, especially gastric cancer.

25 Feb 2008

XYNTHA approved for teatment of hemophilia A by FDA

Wyeth Pharmaceuticals, a division of Wyeth ( NYSE:WYE) , announced today that it has received approval from the U.S. Food and Drug Administration for XYNTHA(TM) (Antihemophilic Factor [Recombinant], Plasma/Albumin-Free), a recombinant factor VIII product, for patients with hemophilia A for both the control and prevention of bleeding episodes and surgical prophylaxis.

22 Feb 2008

New understanding of how big molecules bind will lead to better drugs, synthetic organic materials

Biological and medical research is on the threshold of a new era based on better understanding of how large organic molecules bind together and recognise each other.

22 Feb 2008

Curcumin reduces heart enlargement and may prevent heart failure

Eating curcumin, a natural ingredient in the spice turmeric, may dramatically reduce the chance of developing heart failure, researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital have discovered.

22 Feb 2008

New proof-of-principle findings that thymic involution can be reversed in humans

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) and the University of California, San Francisco (UCSF) have found that therapy can be used to stimulate the production of vital immune cells, called "T- cells," in adults with HIV infection.

21 Feb 2008

Genetic defect causes immune deficiency and balance disorder

A genetic defect that causes a severe immune deficiency in humans may also produce balance disorders, according to a new study by researchers at the University of Iowa, The Jackson Laboratory and East Carolina University.

21 Feb 2008

Deficiency in the protein MBL2 linked to increased cystic fibrosis severity

Cystic fibrosis (CF), a hereditary disorder causing thick mucous production and frequent lung infections, is associated with a high mortality rate primarily due to lung failure.

21 Feb 2008

Biochemists reveal details of mysterious bacterial microcompartments

UCLA biochemists and colleagues have answered an important question about the structure of microcompartments - the mysterious molecular machines that seem to be present in a wide variety of pathogens and other bacteria.

21 Feb 2008

Researchers determine structure of protein that mutates DNA of the AIDS virus HIV-1

Understanding the structure of proteins involved in inhibiting HIV-1 infection could help in the battle against AIDS, and University of Minnesota researchers have taken a crucial step in that direction.

21 Feb 2008

Test for blood sugar not accurate in diabetic dialysis patients

The standard test for measuring blood sugar control in people with diabetes is not accurate in those on kidney hemodialysis, according to new research at Wake Forest University Baptist Medical Center.

21 Feb 2008

Standard test for blood sugar control not accurate in diabetic dialysis patients

21 Feb 2008

Brain's serotonin system differs between men and women

A new thesis from the Swedish medical university Karolinska Institutet shows that the brain's serotonin system differs between men and women.

21 Feb 2008

New method for detecting HER2 breast cancer

Generations of mothers have served up chicken soup to remedy the common cold, but now the therapeutic fowl may find use in diagnosis as well.

21 Feb 2008

Discovery of gene expression pathway that influences process of oxidative stress

The same chemical reaction that causes iron to rust plays a similarly corrosive role in our bodies.

21 Feb 2008

Mutation in TDP-43 gene may play role in common dementia

Scientists at Washington University School of Medicine in St. Louis have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig's disease.

21 Feb 2008

Drinking milk may help women lower risk for hypertension

Women who drank more fat free milk and had higher intakes of calcium and vitamin D from foods, and not supplements, tended to have a lower risk for developing hypertension or high blood pressure, according to a new study published in the American Heart Association journal, Hypertension.

21 Feb 2008

New technique to identify, treat bacterial infections

A new technique developed by a University of Central Florida chemist will help physicians more quickly identify the bacterial infections patients have so they can be treated in hours instead of days.

20 Feb 2008

Single microRNA plays role in innate immune response

Over the last few years scientists have discovered hundreds of microRNAs - tiny RNAs that regulate the expression of protein-coding genes.

20 Feb 2008

Heat shock protein 90 helps explain the speed of evolution

Heat shock protein 90 (HSP90) has a greater impact on the appearance of new traits than previously expected, according to two articles published in the Proceedings of the National Academy of Science (PNAS) by researchers in Whitehead Member Susan Lindquist's lab and their colleagues in Christine Queitsch's lab at Harvard University's FAS Center for Systems Biology.

20 Feb 2008