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Hereditary cardiac amyloidosis more common in the UK than previously thought

More people in the UK are at risk of a hereditary form of cardiac amyloidosis, a potentially fatal heart condition, than previously thought, according to a new study led by researchers at UCL (University College London) and Queen Mary University of London.

28 Aug 2024

Targeting cancer cells by cutting off essential nutrients and backup supplies

Cancer cells have voracious appetites. And there are certain nutrients they can't live without. Scientists have long hoped they might stop tumors in their tracks by cutting off an essential part of cancer cells' diet.

28 Aug 2024

TCT 2024 to feature latest advances in interventional cardiovascular medicine

The Cardiovascular Research Foundation is pleased to announce the late-breaking clinical trials and science to be featured at TCT 2024.

28 Aug 2024

Cell therapy commercialization: Streamline your path to cell therapy commercialization

Moving your cell therapy clinical trial beyond Phase I is an exciting time, marking a significant milestone. There are many therapeutic developers working to address critical patient needs in oncology, auto-immune, regenerative medicine, and other spaces.

From Charles Rivers Laboratories Cell and Gene Therapy 28 Aug 2024

Unraveling the mystery of viral evolution

All organisms - from fungi to mammals - have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with the ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

Simple intervention offers relief for burned-out nurses in Missouri

Even before the coronavirus pandemic, high rates of burnout and staffing shortages plagued the nursing industry, primarily because of the stressful demands of the job.

27 Aug 2024

NIH funds study on psychedelics' potential to treat methamphetamine addiction

John McCorvy, PhD, Assistant Professor in the Department of Cell Biology, Neurobiology, and Anatomy at the Medical College of Wisconsin (MCW); Adam Halberstadt, PhD, Professor of Psychiatry at the University of California San Diego (UCSD) and Director of the UCSD Center for Psychedelic Research; and Kevin Murnane, PhD, Associate Professor of Pharmacology, Toxicology, and Neuroscience and Director of Basic Science Research for the Louisiana Addiction Research Center at LSU Health Shreveport, were recently awarded a five-year, $2.4 million research grant from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), to uncover critical insights into how psychedelics could be used as a therapeutic to treat methamphetamine addiction.

27 Aug 2024

New insights into γδ T cells could improve treatment for colorectal cancer

The most common form of colorectal cancer, microsatellite-stable colorectal cancer (MSS CRC), can currently only be treated to a limited extent with modern immunotherapies.

27 Aug 2024

New insights on how melanoma cells resist cancer immunotherapy

Immune checkpoint inhibitors are cancer fighting drugs that help the immune system do its job of detecting and attacking tumor cells.

27 Aug 2024

Common chemotherapy supplement weakens the pancreatic cancer's defenses in mice

The fight against cancer is an arms race, and one of the most effective weapons in clinicians' arsenals is immunotherapy. Immune checkpoint therapy has become the standard for treating several types of cancer.

27 Aug 2024

AI enhances understanding of radiation-induced cardiac arrhythmia risk in lung cancer patients

Researchers from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, have used artificial intelligence tools to accelerate the understanding of the risk of specific cardiac arrhythmias when various parts of the heart are exposed to different thresholds of radiation as part of a treatment plan for lung cancer.

27 Aug 2024

UQ study unlocks potential for advanced bladder cancer immunotherapy

University of Queensland research could lead to a more effective immunotherapy treatment against bladder cancer.

27 Aug 2024

New benchmark: 1 kg of plasmid DNA manufactured

Kaneka Eurogentec sets new benchmark in plasmid DNA manufacturing with the production of 1 kg of plasmid DNA.

From Kaneka Eurogentec S.A 27 Aug 2024

Study identifies Gα13 as a key tumor suppressor in ER+ breast cancer

In looking for new ways to fight breast cancer, scientists from Duke-NUS Medical School have unmasked a surprising role of a protein generally associated with cancer growth. They have discovered that in estrogen receptor-positive (ER+) breast cancer, this protein acts as a tumor suppressor instead. ER+ breast cancer constitutes about 80 percent of all breast cancer diagnoses, yet nearly 50 percent of women diagnosed with it experience a relapse after initial treatment.

27 Aug 2024

Renewed interest in psychedelics as potential addiction therapies

After years of being seen as dangerous "party drugs," psychedelic substances are receiving renewed attention as therapies for addiction -- but far more research is needed, according to a new special series of articles in the Journal of Studies on Alcohol and Drugs, published at Rutgers University.

26 Aug 2024

GLP-1 therapy boosts visceral fat metabolism, driving weight loss

Researchers discuss the role of enhanced visceral adipose tissue metabolism in mediating weight loss by glucagon-like peptide-1 drugs.

26 Aug 2024

Total neoadjuvant therapy shows promising results in routine care for advanced rectal cancer

Research on a modified TNT regimen for high-risk rectal cancer reveals similar complete response rates and lower toxicity compared to traditional approaches.

26 Aug 2024

Strength training triggers key mechanisms for cellular waste clearance

The elimination of damaged cell components is essential for the maintenance of the body's tissues and organs.

23 Aug 2024

Hybrid cognitive behavioral therapy shows lasting benefits for pediatric anxiety and OCD

Jacqueline Sperling, PhD, a clinical psychologist and assistant professor of Psychology at Harvard Medical School, and co-program director of the McLean Anxiety Mastery Program, led a study investigating the sustainability of outcomes from an intensive group and family-based outpatient cognitive behavioral treatment (CBT) program, that included a hybrid of in-person and virtual treatment sessions for children and adolescents with anxiety disorders and/or obsessive-compulsive disorder (OCD).

23 Aug 2024