Antigen News and Research

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Soligenix, Emergent BioSolutions sign development agreement

Soligenix, Inc., a late-stage biopharmaceutical company developing products that address unmet medical needs in the areas of inflammation, oncology and biodefense, announced today that it has initiated a development agreement with Emergent BioSolutions to implement a commercially viable, scalable production technology for the RiVax drug substance protein antigen.

13 May 2015

Australian researchers discover rogue germinal centre B cells that trigger autoimmune disease

Australian researchers believe they have discovered a group of cells that trigger autoimmune disease, as well as the molecular 'trigger guard' that normally holds them in check.

13 May 2015

World renowned surgeon evaluates parallels between Prostate cancer, Breast cancer

World renowned robotic prostate cancer surgeon, Dr. David Samadi, evaluates the parallels between Prostate cancer and Breast cancer. Prostate cancer is just as common in men as breast cancer is in women with over 233,000 cases diagnosed each year.

12 May 2015

Dana-Farber/Boston Children's joins immunotherapy clinical trial for children with ALL

Dana-Farber/Boston Children's Cancer and Blood Disorders Center has joined a clinical trial of immunotherapy for children with relapsed or treatment-resistant acute lymphoblastic leukemia (ALL). Led by Memorial Sloan Kettering Cancer Center, the trial is one of several nationally that are evaluating cancer immunotherapy, a treatment approach -- hailed by Science magazine as their Breakthrough of the Year in 2013 -- that triggers a patient's immune system to attack his or her cancer cells.

11 May 2015

GenVec reports net loss of $1.5 million for first quarter 2015

GenVec, Inc. today reported financial results for the first quarter ended March 31, 2015. For the three months ended March 31, 2015, GenVec reported a net loss of $1.5 million, or $0.09 per share, on revenues of $0.4 million, compared with a net loss of $1.0 million, or $0.07 per share, on revenues of $2.1 million, for the same period in the prior year.

8 May 2015

Transition Therapeutics acquires worldwide rights from Lilly to develop, commercialize TT701

Transition Therapeutics Inc. today announced its wholly-owned subsidiary, Transition Therapeutics Ireland Limited, has exclusively licensed worldwide rights to a novel small molecule drug candidate ("TT701") from Eli Lilly and Company.

6 May 2015

Study shows that periodontal treatment can reduce symptoms of prostatitis

Treating gum disease reduced symptoms of prostate inflammation, called prostatitis, report researchers from Case Western Reserve University School of Dental Medicine and the Departments of Urology and Pathology at University Hospitals Case Medical Center.

6 May 2015

Antigen-loaded porous silicon microparticles can boost effectiveness of breast cancer vaccines

The effectiveness of cancer vaccines could be dramatically boosted by first loading the cancer antigens into silicon microparticles, report scientists from Houston Methodist and two other institutions in an upcoming Cell Reports (early online).

6 May 2015

Protein Sciences, CTH@H to provide Flublok vaccine to home health and hospice agencies in Connecticut

Protein Sciences Corporation, along with The Connecticut Association for Healthcare at Home, announced a new partnership today that will bring Flublok influenza vaccine to home health and hospice agencies across the state. As a new affinity partner of CTH@H, Protein Sciences will make Flublok available to CTH@H member agencies for the 2015/16 flu season.

5 May 2015

TxCell presents preclinical efficacy and tolerability data for Col-Treg at 2015 ARVO Annual Meeting

TxCell SA, a biotechnology company developing innovative, personalized T-cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, today announces that activity and tolerance data for its second lead product Col-Treg were presented through a poster presentation at the 2015 ARVO Annual Meeting, May 3-7, 2015, in Denver, Colorado, US.

5 May 2015

T cell expansion technology: an interview with Alexander Malykhin, CVPF, University of Pennsylvania

T cells are taken from the patient’s blood and then modified using lentivirus, adenovirus or RNA electroporation.

From Beckman Coulter Life Sciences - Flow Cytometry 5 May 2015

Novel Ga-68-PSMA-ligand PET/CT effective for early detection of prostate cancer recurrence

A recent study reported in The Journal of Nuclear Medicine compared use of the novel Ga-68-PSMA-ligand PET/CT with other imaging methods and found that it had substantially higher detection rates of prostate-specific membrane antigen (PSMA) in patients with biochemical recurrence after radical prostatectomy.

5 May 2015

Pre-POINT trial raises hope for Type 1 diabetes prevention

Giving oral insulin to children at genetic high risk of diabetes stimulates a regulatory immune response without inducing hypoglycaemia, show the findings of the Pre-POINT study.

1 May 2015

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

Scientists at Texas Biomedical Research Institute have begun work on a nearly $3.4 million study funded by the National Institutes of Health over the next four years to create an attenuated, or weakened, virus that is a hybrid of the papilloma virus and the human immunodeficiency virus, with the potential to jumpstart a body's immune response to develop antibodies against both viruses.

30 Apr 2015

Scientists report efficient way to transform A and B blood into neutral type

Every day, thousands of people need donated blood. But only blood without A- or B-type antigens, such as type O, can be given to all of those in need, and it's usually in short supply. Now scientists are making strides toward fixing the situation. In ACS' Journal of the American Chemical Society, they report an efficient way to transform A and B blood into a neutral type that can be given to any patient.

30 Apr 2015

TDF switch effective in Asian chronic HBV patients

Switching therapy to tenofovir disoproxil fumarate is effective in treatment-resistant chronic hepatitis B, show results from a cohort of Asian patients.

29 Apr 2015

Scientists reveal complex role of soy in preventing and advancing breast cancer

Scientists have mapped the human genes triggered by the phytonutrients in soy, revealing the complex role the legume plays in both preventing and advancing breast cancer.

29 Apr 2015

New T1D Prevention Initiative launched to identify pathways to prevent type 1 diabetes

As the incidence of type 1 diabetes (T1D) rises worldwide, The Leona M. and Harry B. Helmsley Charitable Trust today announced the launch of an ambitious new T1D Prevention Initiative to investigate the early stages of development of the disease and identify new pathways to prevent it.

28 Apr 2015

Novel immunotherapeutic shows promise against chronic hepatitis B

A novel immunotherapeutic in early development for chronic hepatitis B (CHB), TG1050, has been shown to reach the clinical goals that are considered to be the hallmarks of a cure for CHB, according to results revealed today at The International Liver Congress 2015.

23 Apr 2015

Scientists identify missing genetic link in common variable immunodeficiency disorder

In the largest genetic study to date of a challenging immunodeficiency disorder, scientists have identified a gene that may be a "missing link" between overactive and underactive immune activity. The gene candidate also plays a key role in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and allergies.

23 Apr 2015

Antigen News and Research

Soligenix, Emergent BioSolutions sign development agreement

Australian researchers discover rogue germinal centre B cells that trigger autoimmune disease

World renowned surgeon evaluates parallels between Prostate cancer, Breast cancer

Dana-Farber/Boston Children's joins immunotherapy clinical trial for children with ALL

GenVec reports net loss of $1.5 million for first quarter 2015

Transition Therapeutics acquires worldwide rights from Lilly to develop, commercialize TT701

Study shows that periodontal treatment can reduce symptoms of prostatitis

Antigen-loaded porous silicon microparticles can boost effectiveness of breast cancer vaccines

Protein Sciences, CTH@H to provide Flublok vaccine to home health and hospice agencies in Connecticut

TxCell presents preclinical efficacy and tolerability data for Col-Treg at 2015 ARVO Annual Meeting

T cell expansion technology: an interview with Alexander Malykhin, CVPF, University of Pennsylvania

Novel Ga-68-PSMA-ligand PET/CT effective for early detection of prostate cancer recurrence

Pre-POINT trial raises hope for Type 1 diabetes prevention

Texas Biomed scientists awarded NIH grant to develop potential HPV-based HIV vaccine

Scientists report efficient way to transform A and B blood into neutral type

TDF switch effective in Asian chronic HBV patients

Scientists reveal complex role of soy in preventing and advancing breast cancer

New T1D Prevention Initiative launched to identify pathways to prevent type 1 diabetes

Novel immunotherapeutic shows promise against chronic hepatitis B

Scientists identify missing genetic link in common variable immunodeficiency disorder

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