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Gene expression ratio linked to prognosis in solid tumors

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

3 Aug 2023

Expression of two key genes influences cancer progression

Tissues, blood vessels, cells: tumours develop in a complex ecosystem known as the tumour microenvironment.

3 Aug 2023

Surprising new role for a key immune regulator revealed

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

3 Aug 2023

Mothers' diet during pregnancy can protect brain health of children and grandchildren

Mothers who eat apples and herbs in early pregnancy could be protecting the brain health of their children and grandchildren, a Monash University study using genetic models has found.

3 Aug 2023

Nanoengineered bioink improves tumor model accuracy

Scientists from the Terasaki Institute for Biomedical Innovation have developed a nanoengineered bioink with improved bonding and cross-linking capabilities for 3D bioprinting of tumor models.

3 Aug 2023

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Researchers discuss the mechanisms of triptans for the treatment of spontaneous migraine attacks by using transcriptomics and metabolomics.

3 Aug 2023

Can genome editing transform ocular disease treatment?

The discovery and development of gene-editing technologies and their applications in managing ocular diseases.

3 Aug 2023

Uncommon genetic allele variants may play a vital role in treatment-resistant depression, finds study

The association between treatment-resistant depression and uncommon functional genetic alleles.

3 Aug 2023

UCLA study finds new way to protect livers during transplantation

UCLA-led research describes the role that a protein called CEACAM1 plays in protecting the liver from injury during the transplantation process, potentially improving transplant outcomes.

2 Aug 2023

Researchers develop new way to detect brain changes associated with schizophrenia

New research led by scientists working with Georgia State University's TReNDS Center has identified age-related changes in brain patterns associated with the risk for developing schizophrenia.

2 Aug 2023

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Individuals with Down syndrome, the genetic condition caused by triplication of human chromosome 21, also known as trisomy 21, display a very high risk of hospitalization and mortality after developing lung infections.

2 Aug 2023

Is there clinical value in screening healthy children with genome sequencing compared with a gene panel for medically actionable pediatric conditions?

Researchers compared the efficacy of proactive genome sequencing and a medically actionable gene panel in identifying potential risk for pediatric-onset disorders in healthy newborns and children.

2 Aug 2023

Study offers deeper understanding of regulatory T cells yielding therapeutic benefits

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

1 Aug 2023

Novel algorithm characterizes RNA motifs in SARS-CoV and SARS-CoV-2

Researchers developed a novel algorithm to analyze large genomic datasets of RNA viruses, applying it to SARS-CoV-2 and SARS-CoV.

1 Aug 2023

Genes News and Research

Gene expression ratio linked to prognosis in solid tumors

Expression of two key genes influences cancer progression

Surprising new role for a key immune regulator revealed

Mothers' diet during pregnancy can protect brain health of children and grandchildren

Nanoengineered bioink improves tumor model accuracy

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Can genome editing transform ocular disease treatment?

Uncommon genetic allele variants may play a vital role in treatment-resistant depression, finds study

UCLA study finds new way to protect livers during transplantation

Researchers develop new way to detect brain changes associated with schizophrenia

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Is there clinical value in screening healthy children with genome sequencing compared with a gene panel for medically actionable pediatric conditions?

Study offers deeper understanding of regulatory T cells yielding therapeutic benefits

Antiviral protein protects against COVID-19 in live mouse models

Scientists develop breakthrough technology for detecting protein modifications

Moving to polluted areas can lead to weight gain in kids

New study spotlights effective strategy against COVID-19 variants: the E7 monoclonal antibody

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Novel algorithm characterizes RNA motifs in SARS-CoV and SARS-CoV-2

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