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Mental Health America urges greater attention to mental health impact of Hurricane Sandy

Mental Health America today said local affiliates in areas affected by Hurricane Sandy are struggling to deliver vital services to fellow citizens and urged greater attention to the mental health impact of the disaster.

3 Nov 2012

Weill Cornell researchers awarded Grand Challenges Explorations grants

Weill Cornell Medical College announced today that it is a Grand Challenges Explorations winner, an initiative funded by the Bill & Melinda Gates Foundation.

3 Nov 2012

Scientists decipher the brain's code for visual working memory in monkeys

The brain holds in mind what has just been seen by synchronizing brain waves in a working memory circuit, an animal study supported by the National Institutes of Health suggests. The more in-sync such electrical signals of neurons were in two key hubs of the circuit, the more those cells held the short-term memory of a just-seen object.

3 Nov 2012

New tool can particularly sort tumor-causing cancer cells

A new tool developed by scientists at The Methodist Hospital separates tumor-causing cancer cells from more benign cells by subjecting the cells to a microscopic game of Plinko -- except only the squishiest cells make it through.

3 Nov 2012

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

A University of Cincinnati (UC) cancer biology team reports breakthrough findings about specific cellular mechanisms that may help overcome endocrine (hormone) therapy-resistance in patients with estrogen-positive breast cancers, combating a widespread problem in effective medical management of the disease.

3 Nov 2012

Researchers develop new technique to predict enzymes known to accelerate diseases

Predicting how atherosclerosis, osteoporosis or cancer will progress or respond to drugs in individual patients is difficult.

3 Nov 2012

CIBMTR renews Stem Cell Therapeutics Outcomes Database contract with HRSA

The Medical College of Wisconsin Center for International Blood and Marrow Transplant Research successfully competed for, and was awarded, renewal of the Stem Cell Therapeutics Outcomes Database contract with the U.S. Health Resources and Services Administration.

3 Nov 2012

New partnership to make advancements in personalized breast cancer treatment and care

The Edith Sanford Breast Cancer Foundation and The Scripps Research Institute today announced the formation of a dynamic partnership that will lay the groundwork for lifesaving advancements in personalized breast cancer treatment and care.

3 Nov 2012

Scientists find new way to unlock cells' destinies

Scientists have discovered that breaking a biological signaling system in an embryo allows them to change the destiny of a cell.

3 Nov 2012

NICE decides to recommend Bristol-Myers Squibb’s YERVOY for treatment of advanced melanoma

Bristol-Myers Squibb Company is pleased to announce that today the National Institute of Health and Clinical Excellence (NICE) has decided to recommend YERVOY (ipilimumab), which is approved in the European Union for the treatment of previously-treated metastatic (advanced) melanoma, within the Final Appraisal Determination (FAD).

3 Nov 2012

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

Weill Cornell Medical College researchers report that mass spectrometry, a tool currently used to detect and measure proteins and lipids, can also now allow biologists to "see" for the first time exactly how drugs work inside living cells to kill infectious microbes.

3 Nov 2012

University of Cambridge forms new spin-out company to supply hIPSC-derived cells

The potential therapeutic applications of stem cells - such as regenerating damaged tissues or organs - have generated a great deal of interest over the past decade. While these types of applications are exciting, it is a long journey from lab to clinic. The most immediate impact of stem cells on human health will most likely come from their use in the development of new drugs.

3 Nov 2012

State of glycocalyx barrier indicates vascular risk in dialysis patients

The glycocalyx barrier – a mesh of proteoglycans and associated glycosaminoglycans present on vascular endothelium – is impaired in patients with renal failure, probably contributing to their predisposition to endothelial dysfunction and vascular disease, say researchers.

2 Nov 2012

Virginia G. Piper, TESARO announce initiation of TSR-011 clinical trial for advanced cancer

TESARO, Inc. announced today that the first clinical trial of its proprietary Anaplastic Lymphoma Kinase (ALK) inhibitor, TSR-011, has commenced with the dosing of the first patient at the Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare, a partnership between Scottsdale Healthcare and the Translational Genomics Research Institute (TGen).

2 Nov 2012

Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.

2 Nov 2012

CD22 protein could prove to be important new target for anti-cancer therapy

A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of the protein with monoclonal antibodies reduced the size of tumors, lowered the occurrence of metastases and substantially lengthened survival time.

2 Nov 2012

New video-protocol details steps to generate human iPSCs from peripheral blood cells

Stem cells are a valuable resource for medical and biological research, but are difficult to study due to ethical and societal barriers. However, genetically manipulated cells from adults may provide a path to study stem cells that avoid any ethical concerns. A new video-protocol in JoVE (Journal of Visualized Experiments), details steps to generate human induced pluripotent stem cells (iPSC) from cells in the peripheral blood.

2 Nov 2012

XJB-5-131 compound suppresses symptoms of Huntington's in mice

There's new hope in the fight against Huntington's disease. A group of researchers that includes scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.

2 Nov 2012

Researchers unlock complex cellular mechanics that instruct glial progenitor cells to divide

In a new study appearing this month in the Journal of Neuroscience, researchers have unlocked the complex cellular mechanics that instruct specific brain cells to continue to divide. This discovery overcomes a significant technical hurdle to potential human stem cell therapies; ensuring that an abundant supply of cells is available to study and ultimately treat people with diseases.

2 Nov 2012

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

Affymax, Inc. and Takeda Pharmaceuticals U.S.A., Inc. (TPUSA) today announced the presentation of post-hoc sub-group analyses of the EMERALD Phase 3 studies that evaluated OMONTYS (peginesatide) Injection, an erythropoiesis-stimulating agent (ESA), for the treatment of anemia due to chronic kidney disease (CKD) in adult dialysis patients.

2 Nov 2012

B Cell News and Research

Mental Health America urges greater attention to mental health impact of Hurricane Sandy

Weill Cornell researchers awarded Grand Challenges Explorations grants

Scientists decipher the brain's code for visual working memory in monkeys

New tool can particularly sort tumor-causing cancer cells

MED1 plays a central role in mediating tamoxifen resistance in breast cancer

Researchers develop new technique to predict enzymes known to accelerate diseases

CIBMTR renews Stem Cell Therapeutics Outcomes Database contract with HRSA

New partnership to make advancements in personalized breast cancer treatment and care

Scientists find new way to unlock cells' destinies

NICE decides to recommend Bristol-Myers Squibb’s YERVOY for treatment of advanced melanoma

Mass spectrometry can help visualize how drugs work inside living cells to kill infectious microbes

University of Cambridge forms new spin-out company to supply hIPSC-derived cells

State of glycocalyx barrier indicates vascular risk in dialysis patients

Virginia G. Piper, TESARO announce initiation of TSR-011 clinical trial for advanced cancer

Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

CD22 protein could prove to be important new target for anti-cancer therapy

New video-protocol details steps to generate human iPSCs from peripheral blood cells

XJB-5-131 compound suppresses symptoms of Huntington's in mice

Researchers unlock complex cellular mechanics that instruct glial progenitor cells to divide

Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD

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