Androgen News and Research

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NIH researchers unravel how male, female mouse embryos acquire sex-specific reproductive systems

A protein called COUP-TFII determines whether a mouse embryo develops a male reproductive tract, according to researchers at the National Institutes of Health and their colleagues at Baylor College of Medicine, Houston.

17 Aug 2017

Mice study shows why women with obesity have more aggressive breast cancer

Women with obesity are more likely to get breast cancer, and a number of studies have provided a reasonable explanation why: after menopause, fat tissue manufactures estrogen, and the estrogen then promotes tumor growth.

8 Aug 2017

Researchers provide evidence supporting need for gender-specific anti-inflammatory drugs

Perhaps you have come across the titles 'Men are from Mars, women are from Venus' or 'Why men don't listen and women can't read maps': just two of the many books and articles -- some enlightening or amusing and others irritating -- that theorise about fundamental differences between men and women.

26 Jul 2017

Excess male hormones in PCOS women contribute to metabolic complications, study shows

Scientists from the University of Birmingham have discovered the link between increased male hormones and metabolic complications such as diabetes and fatty liver disease in patients with polycystic ovary syndrome.

23 Jun 2017

Moffitt researchers develop novel drug that may help combat castration-resistant prostate cancer

Prostate cancer is the third most common cause of cancer-related death in men in the United States. It is estimated that 161,360 men will be diagnosed and more than 26,700 men will die from the disease in this year.

12 Jun 2017

Study explores effects of androgen deprivation therapy on overall geriatric health

Androgen drives many prostate cancers. But the body uses androgen for muscle growth and maintenance, among other functions.

5 Jun 2017

Standard therapy plus abiraterone lowers relative risk of death in men with advanced prostate cancer

A clinical trial of nearly 2,000 men shows that adding abiraterone acetate (Zytiga) to a standard initial treatment regimen for high-risk, advanced prostate cancer lowers the relative risk of death by 37%.

5 Jun 2017

Precise delivery of HDR brachytherapy provides good quality of life to prostate cancer patients

Doctors have found that treating prostate cancer with a single, high dose of radiation delivered precisely to the site of the tumor results in good quality of life and fewer trips to the hospital, with adverse side effects that are no worse than if the radiation treatment had been given in several lower doses.

8 May 2017

Molecular mechanism reprograms tumor cells to drive treatment resistance in advanced prostate cancer

Columbia University Medical Center researchers have discovered a molecular mechanism that reprograms tumor cells in patients with advanced prostate cancer, reducing their response to anti-androgen therapy.

4 May 2017

Combined treatment regimen shows early promise in eliminating metastatic prostate cancer

In the past, all forms of metastatic prostate cancer have been considered incurable. In recent years, the FDA has approved six drugs for men with metastatic disease, all of which can increase survival.

18 Apr 2017

Clinical study examines impact of yoga on side-effects caused by prostate cancer treatment

Men who attended a structured yoga class twice a week during prostate cancer radiation treatment reported less fatigue and better sexual and urinary function than those who didn't, according to a clinical trial led by the Perelman School of Medicine at the University of Pennsylvania.

6 Apr 2017

Treating PCOS in adolescent girls may help prevent future subfertility, research suggests

In adolescent girls with polycystic ovary syndrome (PCOS), bringing the amount of abdominal visceral fat and liver fat down to normal restores ovulation, normalizes the symptoms of androgen excess, and may help prevent future subfertility, new research from Spain suggests.

4 Apr 2017

Amgen, UCB present romosozumab Phase 2 results at ENDO 2017

Amgen and UCB today announced results from the fourth year of a Phase 2 study showing the efficacy and safety of a second course of treatment with EVENITY™* (romosozumab), an investigational agent for postmenopausal women with osteoporosis.

3 Apr 2017

Novel highly potent SARDs may offer treatment option for advanced prostate cancer, study reports

Novel molecules called selective androgen receptor degraders (SARDs) may offer the next generation of treatment options for advanced prostate cancer, a new industry-sponsored study reports. The results of this research will be presented Saturday, April 1, at ENDO 2017, the 99th annual meeting of the Endocrine Society, in Orlando, Fla.

2 Apr 2017

QIAGEN announces commercialization of AdnaTest kit for clinical research in prostate cancer

QIAGEN N.V. today announced it is commercializing the Research use only AdnaTest Prostate Cancer Panel AR-V7 to detect the androgen receptor splice variant 7 (AR-V7) from liquid biopsies to investigate resistance to potential drugs for advanced prostate cancer.

From QIAGEN Manchester Limited 31 Mar 2017

New analysis shows correlation between testosterone-lowering therapy for prostate cancer and dementia

A new analysis of patients who have undergone treatment for prostate cancer shows a connection between androgen deprivation therapy (ADT) - a testosterone-lowering therapy and a common treatment for the disease - and dementia, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

30 Mar 2017

Androgens more important for ovarian development, study suggests

Scientists have discovered that the male "androgen" hormone is an important element in the ovarian development of female chicken embryos, more so than in the development of male testes.

23 Mar 2017

Direct-to-consumer ‘low-T’ medication advertising increases prescriptions but may not improve health

Direct-to-consumer advertising for drugs to treat testosterone deficiency -- or "low T" -- increases prescriptions to men for hormone-replacement therapies but may not improve their health, UC Davis physician Richard Kravitz said in an editorial published in the March 21 issue of the Journal of the American Medical Association.

22 Mar 2017

Novel androgens play major role in development of PCOS, research shows

Scientists led by the University of Birmingham have discovered that a new class of male sex hormones known as androgens plays a key role in the development of polycystic ovary syndrome (PCOS).

13 Mar 2017

Mayo study provides vital information on tumor sequencing in newly diagnosed breast cancer patients

Tumor sequencing is increasingly used to select treatment for patients with cancer, but its role in women with newly diagnosed breast cancer is unknown.