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Research uncovers new clues to combat dengue and Zika virus

Structural biology research conducted at the U.S. Department of Energy's SLAC National Accelerator Laboratory has uncovered how small insecticidal protein crystals that are naturally produced by bacteria might be tailored to combat dengue fever and the Zika virus.

28 Sep 2016

Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

My research lab studies several classes of systems. We are mostly interested in looking at large protein assemblies to understand their structure, dynamics and how their properties relate to their malfunction in disease.

From Bruker BioSpin Division 21 Sep 2016

AXT to exclusively distribute Unchained Labs biologics research tools in Australia, New Zealand

AXT is excited to announce that they have partnered with Unchained Labs and will now be exclusively distributing their innovative and novel range of instruments for the analysis and formulation of biologics in Australia and New Zealand.

From AXT Pty Ltd 20 Sep 2016

Scientists begin research work at new £650 million Francis Crick Institute building

The first scientists have moved into the new £650 million Francis Crick Institute building in London and are starting work in their purpose-built labs.

20 Sep 2016

Research could pave way for more effective and safer anti-epilepsy drugs

Columbia University Medical Center researchers have discovered how a new epilepsy drug works, which may lead the way to even more effective and safer medications.

8 Sep 2016

Research findings of protein may form foundation for new approach to antibiotics

Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics.

1 Sep 2016

Mitosis study identifies new potential target for cancer therapy

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy.

31 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

EPFL scientists discover new path to combat pathogenic bacteria

Bacteria that cause tuberculosis, leprosy and other diseases, survive by switching between two different types of metabolism.

24 Aug 2016

Novel nanoscale display case could help reveal structure of hard-to-study molecules

Researchers at the Department of Energy's Lawrence Berkeley National Laboratory and UC Berkeley have created a sort of nanoscale display case that enables new atomic-scale views of hard-to-study chemical and biological samples.

19 Aug 2016

Researchers develop new hybrid method to study HIV protein involved in disease progression

More than 36 million people worldwide, including 1.2 million in the U.S., are living with an HIV infection. Today's anti-retroviral cocktails block how HIV replicates, matures and gets into uninfected cells, but they can't eradicate the virus.

3 Aug 2016

Scientists unveil structure of Zika NS1 protein

Researchers have revealed the molecular structure of a protein produced by the Zika virus that is thought to be involved in the virus's reproduction and its interaction with a host's immune system.

26 Jul 2016

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Neutron crystallography allows us to determine the three-dimensional structures of biological macromolecules, such as proteins, by means of the diffraction of neutrons from the regularly spaced atoms of a crystal.

21 Jul 2016

Scientists capture new images of calcium-shuttling molecule linked to aggressive cancers

Scientists have captured new images of a calcium-shuttling molecule that has been linked to aggressive cancers. The three-dimensional structure could help researchers develop novel therapies and diagnostic tools for diseases that are caused by a malfunction in calcium adsorption.

18 Jul 2016

Findings offer renewed hope for speedy development curative medicines for people with toxoplasmosis

In the July 14 edition of Scientific Reports (Nature), 39 researchers from 14 leading institutions in the United States, United Kingdom and France suggest novel approaches that could hasten the development of better medications for people suffering from toxoplasmosis.

17 Jul 2016

Researchers reveal molecular mechanism of autophagy initiation

Researchers revealed that Atg13 links autophagy initiation factors to each other using a string-like conformation, thereby promoting the association of diverse elements of the autophagy initiation machinery, initiating autophagosome formation through the recruitment of Atg9 vesicles and phosphorylation of various Atg factors.

12 Jul 2016

Crystallography News and Research

Research uncovers new clues to combat dengue and Zika virus

Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

AXT to exclusively distribute Unchained Labs biologics research tools in Australia, New Zealand

Scientists begin research work at new £650 million Francis Crick Institute building

Research could pave way for more effective and safer anti-epilepsy drugs

Research findings of protein may form foundation for new approach to antibiotics

Mitosis study identifies new potential target for cancer therapy

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

EPFL scientists discover new path to combat pathogenic bacteria

Novel nanoscale display case could help reveal structure of hard-to-study molecules

Researchers develop new hybrid method to study HIV protein involved in disease progression

Scientists unveil structure of Zika NS1 protein

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Scientists capture new images of calcium-shuttling molecule linked to aggressive cancers

Findings offer renewed hope for speedy development curative medicines for people with toxoplasmosis

Researchers reveal molecular mechanism of autophagy initiation

Researchers uncover sensing mechanism of food poisoning bacteria found in shellfish

Scientists isolate antibodies capable of neutralizing dengue and Zika virus

UT Southwestern study offers more insight into cholesterol transporter

Breakthrough study observes structural changes in carbonic anhydrase for first time

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