Depressive Disorder News and Research

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Study reveals safety, efficacy of brexpiprazole for schizophrenia patients with severe psychotic symptoms

Otsuka Pharmaceutical Co., Ltd. and H. Lundbeck A/S announced study results on the safety and efficacy of brexpiprazole in the treatment of patients with schizophrenia experiencing severe psychotic symptoms during an acute episode. The data will be presented at the upcoming Psych Congress, held in Orlando from October 25-28, 2018.

26 Oct 2018

Supervised aerobic exercise can support major depression treatment

An analysis of randomized controlled clinical trials indicates that supervised aerobic exercise has large antidepressant treatment effects for patients with major depression. The systematic review and meta-analysis is published in Depression and Anxiety.

18 Oct 2018

Antidepressant treatment may lead to improvements in sleep quality of patients with depression

In a study of 15 patients affected by major depressive disorder and complaining of insomnia, initiating treatment with vortioxetine for their depressive symptoms led to significant improvements in subjective sleep quality and daytime sleepiness.

17 Oct 2018

Research provides a more complete picture of suffering caused by terrorist attacks

Terrorist attacks injure far more people than they kill, leaving victims with lost limbs, hearing loss, respiratory disease, depression and other issues. But little research has measured the impact of that damage beyond the number of people who are hurt.

15 Oct 2018

DNA of people with depression, trauma is biologically older than healthy individuals

DNA from people who suffer from major depression is biologically older than that of healthy people by on average 8 months, suggesting that they are biologically older than their corresponding calendar age.

8 Oct 2018

Experts warn health care providers to slow down in allowing smart pill in patient care settings

Enthusiasm for an emerging digital health tool, the smart pill, is on the rise but researchers at the University of Illinois at Chicago have published a paper in the American Journal of Bioethics that cautions health care providers and policymakers to slow down when it comes to allowing this technology in patient care settings.

21 Sep 2018

Brain region for stress control is enlarged in people with depression, finds study

According to the World Health Organization, 322 million people worldwide were affected by depression in 2015--4.4 percent of the world's population.

20 Sep 2018

Childhood adversity associated with impaired social cognition in adults with major psychiatric disorders

A new report published in European Psychiatry identified a significant association between childhood adversity and impaired social cognitive functioning among adults diagnosed with major psychiatric disorders.

12 Sep 2018

WVU researcher works to improve treatment access for rural depressed patients

Rates of depression tend to be higher in rural areas than in urban ones, yet rural residents may have a harder time accessing mental health care. Driving to see a psychiatrist or counselor may take hours, and wait times for an appointment may take months.

6 Sep 2018

New guidelines for evaluation and treatment of perimenopausal depression

It is well-recognized that women are at increased risk of depression during postpartum when hormone levels are changing, but the risk of depression associated with perimenopause -- the time right before menopause when female hormones are in decline -- remains under-recognized and clinical recommendations on how to diagnose and treat this kind of depression in women have been lacking until now.

5 Sep 2018

Looking deep inside the brain to accurately diagnose bipolar disorder and depression

New research has found that neurons deep inside the brain could hold the key to accurately diagnosing bipolar disorder and depression.

4 Sep 2018

Study explores how social networks affect smoking outcomes in people with serious mental illness

People with serious mental illness have a reduced life expectancy of up to 25 years compared to the general population

24 Aug 2018

BrainsWay receives FDA clearance for Deep TMS system to treat adults with obsessive-compulsive disorder

BrainsWay Ltd., the parent company of BrainsWay USA, Inc., and a global leader in the advanced non-invasive treatment of brain disorders, today announces that it has received De Novo clearance from the U.S. Food and Drug Administration (FDA) for its deep transcranial magnetic stimulation (Deep TMS) system for the treatment of obsessive-compulsive disorder (OCD) in adults.

22 Aug 2018

Scientists make surprising discovery in nerve cells

Purkinje cells are a central part of the human cerebellum, the part of the brain that plays an important role in motor learning, fine motor control of the muscle, equilibrium and posture but also influences emotions, perception, memory and language.

10 Aug 2018

New AI algorithm helps predict medication response in patients with complex mood disorder

Mood disorders like major depressive disorder and bipolar disorder are often complex and hard to diagnose, especially among youth when the illness is just evolving.

9 Aug 2018

Researchers identify neural link between depression and sleep problems

The neural link between depression and sleep problems has been identified for the first time in a new study by researchers at the University of Warwick and Fudan University.

25 Jul 2018

Nitrate-cured meats may contribute to mania, study finds

An analysis of more than 1,000 people with and without psychiatric disorders has shown that nitrates-chemicals used to cure meats such as beef jerky, salami, hot dogs and other processed meat snacks-may contribute to mania, an abnormal mood state. Mania is characterized by hyperactivity, euphoria and insomnia.

18 Jul 2018

Scientists develop new understanding of how psychiatric diseases manifest and can be treated

Research scientists from The Feinstein Institute for Medical Research and the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell in Hempstead, NY, in conjunction with their colleagues at Rockefeller University in New York City, have developed a new understanding of how certain psychiatric diseases - those that involve uncontrollable reactions to stimuli such as the high and low experiences attributed to bi-polar disorder, the impulsivity of an individual suffering from attention deficit hyperactivity disorder, and even suicidality - manifest and potentially can be treated. These findings were published today in Proceedings of the National Academy of Sciences.

3 Jul 2018

Massive analysis of genomes reveals insights into genetic overlap among psychiatric diseases

A massive undertaking by the Brainstorm Consortium to analyze the genomes of nearly 900,000 people has revealed important insights into the genetic overlap among some psychiatric diseases, as well as among personality traits.

21 Jun 2018

Osteoarthritis patients with greater disease severity may have higher risk of depression

Two measures of disease severity cumulatively contribute to depressive symptom onset; physical performance and structural severity

14 Jun 2018