ELISA News and Research

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On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

In a new study posted to the medRxiv* preprint server, researchers in China developed an MPXV assay combining clustered regularly interspaced short palindromic repeats and CRISPR-associated protein (CRISPR/Cas) and recombinase-aided amplification (RAA) for the first time.

18 Oct 2022

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

In a new study, researchers determined plasma signatures of proteins related to or derived from platelets in acute isolated pulmonary embolism (iPE) and deep vein thrombosis-associated PE (DVT-PE), compared to isolated DVT (iDVT).

17 Oct 2022

Owner SARS-CoV-2 RNA load shown to be associated with infection in pet dogs

A new study assessed the potential association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) load in owners with SARS-CoV-2 infection in their dogs.

17 Oct 2022

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

Researchers examined single clones of SARS-CoV-2-specific memory B cells to understand their adaptability and fate.

13 Oct 2022

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

A new study aimed to analyze the immunometalobism BALF cells from mild to severe COVID-19 patients using computational algorithms that quantified metabolic fluxes and metabolic pathways.

13 Oct 2022

Modeling the risk factors for household transmission of SARS-CoV-2

Researchers analyze the risks of contracting SARS-CoV-2 from the household and community

12 Oct 2022

Evaluating graphene field effect biosensor for ultraprecise and simultaneous influenza and SARS-CoV-2 detection

In a new study, researchers developed an antibody (Ab)-modified graphene field effect transistor (GFET)-based biosensor for ultraprecise and rapid influenza A virus (IAV) and SARS-CoV-2 protein detection and differentiation.

10 Oct 2022

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

In a new study, researchers investigated the breadth and longevity of immunity induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure among the Kenyan population.

10 Oct 2022

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

In a new study, researchers assessed the safety, efficacy, and immunogenicity of a candidate SARS-CoV-2 subunit vaccine in black-footed ferrets (BFF), and investigated the susceptibility of these endangered North American mammals to the virus.

7 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Researchers explored SARS-CoV-2-targeted immune responses among COVAC1 participants who received a novel saRNA vaccine followed by the mRNA BNT162b2 vaccine BNT162b2 vaccine, with or without prior COVID-19 history.

7 Oct 2022

$The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series$

The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series

Researchers evaluated the vaccine effectiveness of half-doses of AZD1222 or BNT162b2 COVID-19 vaccines as a booster dose following primary series vaccination with CoronaVac.

6 Oct 2022

PerkinElmer’s Oxford Immunotec receives U.S. FDA approval for T-cell select to automate clinically superior tuberculosis detection

PerkinElmer’s (NYSE: PKI) Oxford Immunotec today announced the U.S. Food and Drug Administration (FDA) has approved the use of the T-Cell Select™ reagent kit for the automation of its T-SPOT®.TB test workflow for in vitro diagnostic (IVD) use by certified laboratories.

From Oxford Immunotec 6 Oct 2022

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Researchers determined the T cell response to the NVX-CoV2373, an adjuvanted recombinant full-length SARS-CoV-2 spike (S) trimer protein vaccine.

5 Oct 2022

Spike-specific memory B cells develop resilience to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers explored the cross-reactivity, avidity, and kinetics of memory B-cells and serum antibodies in vaccinated and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals.

4 Oct 2022

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Researchers developed a high-throughput, rapid antigen SARS-CoV-2 spike protein detection test using allonamers, a new type of aptamers that carry out allosteric regulation instead of catalytic activity.

28 Sep 2022

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

In a new study, a team of researchers demonstrated that testicular injury in humans is not due to direct SARS-CoV-2 infection but more likely is an indirect effect of exposure to systemic inflammation or SARS-CoV-2 antigens.

26 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

In a recent study posted to the medRxiv* preprint server, researchers in the United States described the safety, efficacy, and immunogenicity of the NVX-CoV2373 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), tested in PREVENT-19 — a phase 3, randomized, placebo-controlled, observer-blinded trial among 12- to 17-year-old adolescents in the United States (U.S).

25 Sep 2022

A good night's sleep promotes immunity

In a recent study published in the Journal of Experimental Medicine, researchers in the United States used mice models to understand how sleep fragmentation affects immunological responses and the epigenetic modifications of hematopoietic stem and progenitor cells (HSPCs). They also conducted a sleep restriction trial in humans to determine HPSC programming and hematopoiesis.

25 Sep 2022

ELISA News and Research

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

Investigating plasma signatures of platelet-derived proteins in acute pulmonary embolism

Owner SARS-CoV-2 RNA load shown to be associated with infection in pet dogs

Study finds memory B cell clones harbor the capacity to adopt multiple and functionally different fates in COVID-19 patients

The immunometabolic regulatory mechanisms for the pathogenesis of COVID-19

Modeling the risk factors for household transmission of SARS-CoV-2

Evaluating graphene field effect biosensor for ultraprecise and simultaneous influenza and SARS-CoV-2 detection

Scientists explore kinetics of naturally induced anti-SARS-CoV-2 antibodies in the Kenyan population

Study evaluates efficacy of a candidate SARS-CoV-2 subunit vaccine to protect endangered black-footed-ferrets

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

The immune responses and safety of fractional third-doses of heterologous COVID-19 vaccines after CoronaVac primary series

PerkinElmer’s Oxford Immunotec receives U.S. FDA approval for T-cell select to automate clinically superior tuberculosis detection

Novel protein vaccine NVX-CoV2373 triggered functional T cell responses to SARS-CoV-2

Spike-specific memory B cells develop resilience to SARS-CoV-2

Q-LAAD: a dynamic, cost-effective rapid antigen test for detection of SARS-CoV-2

Systemic inflammation triggered by SARS-CoV-2 found to cause human testicular injury

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Trial tests efficacy and safety of NVX-CoV2373 COVID-19 vaccine among adolescents

A good night's sleep promotes immunity

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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