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Research offers a phylogenetic and ontogenetic overview of the primitive streak

In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of Virginia Health System, USA) offer a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, and discuss the implications of embryonic stem cell-based models of early mammalian embryogenesis on the function of this structure.

4 Dec 2021

Non-coding RNA plays a key role in regulating behavior of chromosome loops and gene expression

An important player in the healthy development of female embryos turns out also to play a key role in regulating the behavior of chromosome loops and gene expression in both sexes, according to a new study by researchers at Massachusetts General Hospital.

2 Dec 2021

Researchers shed light on an important stage of early human embryogenesis for the first time

Scientists have shed light on an important stage of early embryonic development that has never been fully mapped out in humans before.

29 Nov 2021

Study discovers new role of Hox genes in adulthood

Among their many extraordinary feats, some planarian flatworms reproduce by tearing off pieces of themselves to regenerate new worms.

18 Nov 2021

GPR126 gene may play an essential role in placental development, study reveals

Scientists working with an experimental mouse model at the Centro Nacional de Investigaciones Cardiovasculares have identified the essential role of the gene GPR126 in the development of the placenta during pregnancy.

12 Nov 2021

New insight into the tremendously complex "genetic dance"

The rapid scientific advancements that followed the mapping of the human genome have revealed just how staggeringly complex the world of genetics is.

28 Oct 2021

Research reveals the mechanisms of cardiac sex disparities at an early stage

Males and females differ in prevalence, treatment responses, and survival rates for a variety of diseases. For cardiac disease, women almost uniformly fare far worse than men. There are likely many reasons for this, and scientists at the University of North Carolina at Chapel Hill and Princeton University seemed to have found one deep inside cells before we're even born.

21 Oct 2021

Researchers develop a new method to remove old cells from tissues to slow down aging

No one knows why some people age worse than others and develop diseases -such as Alzheimer's, fibrosis, type 2 diabetes or some types of cancer- associated with this ageing process.

20 Oct 2021

UGA study makes breakthrough for treatment of male infertility

With global rates of male infertility continuing to rise, a new study in spermatogonial stem cell research led by researchers at the University of Georgia provides hope for future clinical therapies.

19 Oct 2021

Study highlights the critical role of junk DNA in mammalian development

Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.

19 Oct 2021

Mothers pass on the legacy of stress exposure to future generations

A mother's response to stress can even influence her grandchildren. Biologists at the University of Iowa found that roundworm mothers subjected to heat stress passed, under certain conditions and through modifications to their genes, the legacy of that stress exposure not only to their offspring but even to their offspring's children.

13 Oct 2021

Using genetic screening for selecting the 'best' embryo in IVF

Each year, tens of thousands of babies are born in the United States as the result of IVF (in vitro fertilization) – where several eggs are fertilized outside the mother's body and then an embryo is selected for transfer into her womb.

12 Oct 2021

Using AI in biology to unravel how cells fight off invaders

Imagine the day when any tissue or organ can be repaired or the replacements personalized to the patient.

7 Oct 2021

Scientists create a novel cell model for understanding human development

The earliest moments of human development—between the time of fertilization and when the embryo implants in the womb—have remained opaque to scientists.

9 Sep 2021

Highly extensive Gut Cell Atlas will transform research into intestinal diseases

Many diseases have their origin in early human development, and today (8th September), two publications in Nature reveal how researchers from the Human Cell Atlas (HCA) consortium are advancing understanding of this.

9 Sep 2021

New, one-stop method developed to avoid de novo genetic disease in embryos

De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have.

31 Aug 2021

Can molecular mimicry impact fertility in female COVID-19 patients?

There exists a possibility that COVID-19 can also affect the reproductive function in the body, which can lead to infertility in infected patients. A study published in the American Journal of Reproductive Immunology explored the impact of SARS-CoV-2 infection on reproductive functions and fertility.

30 Aug 2021

Mystery of roe deer embryonic diapause revealed

Everyone is familiar with the roe deer, either from crossword puzzles or from real-life encounters during a jog or a hike in the forest: majestic creatures with elegant big black eyes.

28 Aug 2021

Novel CRISPR-based technology for rapidly screening genes to understand human health and disease

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

20 Aug 2021

Blue light can activate key signaling pathway that plays role in embryonic development and cancer

Blue light is illuminating new understanding of a key signaling pathway in embryo development, tissue maintenance and cancer genesis.

17 Aug 2021