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New JIC research helps to settle important debate on epigenetic inheritance

New research findings by John Innes Centre scientists have helped to settle an important debate in the field of epigenetic inheritance. Using the flowering plant Arabidopsis thaliana as a model for their research, Professor Martin Howard, Professor Caroline Dean and members of their labs, have been trying to understand how organisms 'remember' past events at the cellular level.

4 Jun 2015

Researchers make important breakthrough in identifying major drivers of excessive coughing

Cough treatments could change dramatically after the herpes virus helped researchers discover that the respiratory tract links to two different parts of the nervous system.

27 May 2015

New microscopy technique helps researchers to selectively visualize individual cells in living organism

Researchers at ETH Zurich's Department of Biosystems Science and Engineering in Basel have developed a new microscopy technique that enables for the first time to selectively visualize individual cells within the complex, three-dimensional tissue of a living organism.

20 May 2015

Overexpression of cyclin E protein could lead to breast cancer, leukemia

A new study led by scientists at The Scripps Research Institute sheds light on the cause of some cancers, including breast cancer and leukemia.

8 May 2015

Gentronix signs three-year technology access deal with SIMM

UK based Gentronix Limited, the specialist genetic toxicology company, today announced it has signed a three year technology access deal with one of China's most prestigious research intensive institutes, Shanghai Institute Materia Medica, Chinese Academy of Sciences.

18 Mar 2015

UT Dallas study reports new gene therapy approach

Bioengineers at The University of Texas at Dallas have created a novel gene-delivery system that shuttles a gene into a cell, but only for a temporary stay, providing a potential new gene-therapy strategy for treating disease.

19 Feb 2015

Understanding the pattern of cellular changes that lead to retinal ganglion cell death in glaucoma

Glaucoma, the second leading cause of blindness, usually stems from elevated eye pressure, which in turn damages and destroys specialized neurons in the eye known as retinal ganglion cells. To better understand these cellular changes and how they influence the progression and severity of glaucoma, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute turned to a mouse model of the disease.

12 Feb 2015

Researchers generate new reporter system to study bone regeneration potential of embryonic stem cells

A new reporter system used to study the bone regeneration potential of human embryonic stem cells has been generated in research led by the University of Minnesota. The new reporter system is the first of its kind for human pluripotent stem cells and is important for identifying certain agents and pathways that mediate early stages of human bone development.

11 Feb 2015

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a major role in ALS pathology.

31 Jan 2015

CUMC researcher develops new 3D microscope that can help view living things at very high speeds

Opening new doors for biomedical and neuroscience research, Elizabeth Hillman, associate professor of biomedical engineering at Columbia Engineering and of radiology at Columbia University Medical Center, has developed a new microscope that can image living things in 3D at very high speeds.

20 Jan 2015

CML mouse model reveals previously unreported facets of disease

A humanised murine model of chronic phase chronic myeloid leukaemia, developed by a Swedish research team, provides insight into previously unexplored characteristics of the disease.

12 Jan 2015

TSRI scientists identify 'mechanoreceptor' protein that mediates sense of touch in mammals

A team led by biologists at The Scripps Research Institute has solved a long-standing mystery in neuroscience by identifying the "mechanoreceptor" protein that mediates the sense of touch in mammals.

5 Dec 2014

Physiologists use new method to identify two odorant receptors in live mice

A group of physiologists led by University of Kentucky's Tim McClintock have identified the receptors activated by two odors using a new method that tracks responses to smells in live mice.

2 Dec 2014

Novel technique uses genetic tool and light to map neural networks

For years, neuroscientists have been trying to develop tools that would allow them to clearly view the brain's circuitry in action-from the first moment a neuron fires to the resulting behavior in a whole organism.

22 Sep 2014

New techniques offer insight into cell-by-cell makeup of organisms

In general, our knowledge of biology-and much of science in general-is limited by our ability to actually see things. Researchers who study developmental problems and disease, in particular, are often limited by their inability to look inside an organism to figure out exactly what went wrong and when.

6 Aug 2014

Study shows that mice can identify specific odors amid complex olfactory environments

For many animals, making sense of the clutter of sensory stimuli is often a matter or literal life or death. Exactly how animals separate objects of interest, such as food sources or the scent of predators, from background information, however, remains largely unknown.

4 Aug 2014

New Tel Aviv University study finds link between Alzheimer's and brain hyperactivity

Patients with Alzheimer's disease run a high risk of seizures. While the amyloid-beta protein involved in the development and progression of Alzheimer's seems the most likely cause for this neuronal hyperactivity, how and why this elevated activity takes place hasn't yet been explained - until now.

1 Jul 2014

Study reveals that inflammasomes remain active even after cell death

Even after a cell dies, components of the immune system remain active and continue to fuel inflammatory reactions.

23 Jun 2014

Sleep helps consolidate, strengthen new memories

In study published today in Science, researchers at NYU Langone Medical Center show for the first time that sleep after learning encourages the growth of dendritic spines, the tiny protrusions from brain cells that connect to other brain cells and facilitate the passage of information across synapses, the junctions at which brain cells meet.

6 Jun 2014

Scientists identify new way to reactivate latent HIV

A team of scientists at the Gladstone Institutes has identified a new way to make latent HIV reveal itself, which could help overcome one of the biggest obstacles to finding a cure for HIV infection.