Genomic News and Research

RSS

ACE2 protein may play a protective role against high blood pressure and type 2 diabetes

A collaborative study from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London has found that the protein ACE2 may play a protective role against two common conditions, high blood pressure and type-2 diabetes, which affect millions of people worldwide.

19 Dec 2025

Social living allows genetic effects to spread through the gut microbiome

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

18 Dec 2025

AI tool reveals hidden proteins in Earth’s vital microalgae

Scientists at NYU Abu Dhabi have developed a powerful new artificial intelligence tool called LA⁴SR that can rapidly identify previously overlooked proteins in microalgae - tiny organisms that produce much of the Earth's oxygen and support entire aquatic ecosystems.

16 Dec 2025

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance demonstrated in studies in mice that could lay the groundwork for safer, more precise treatments for cancer and other diseases.

16 Dec 2025

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

An Thought Leaders Invited Review published today in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual identity.

16 Dec 2025

SARS-CoV-2 evolves after jumping from humans to zoo animals

Research on SARS-CoV-2 in zoo tigers, lions, and hyenas shows rapid viral evolution and adaptation, offering insights into cross-species transmission dynamics.

16 Dec 2025

Indoor tanning loads normal skin with mutations linked to melanoma

Indoor tanning is associated with markedly higher mutation burdens and cancer-driving genetic changes in melanocytes taken from normal-appearing skin, including areas usually protected from sunlight. These molecular alterations provide a biological explanation for the higher odds of melanoma and multiple primary tumors seen in heavy tanning bed users.

15 Dec 2025

New initiative aims to transform care for early-onset cancer patients

More people under age 50 are developing cancer, and with that comes a shift in the model of care needed to serve this unique cancer patient population – including early access to fertility counseling, universal genomic testing to identify underlying genetic drivers, support resources to address long-term survivorship considerations, and community education regarding early detection and screening.

15 Dec 2025

Novel AI tool not only identifies genetic mutations but also predicts the type of disease

Scientists at the Icahn School of Medicine at Mount Sinai have developed a novel artificial intelligence tool that not only identifies disease-causing genetic mutations but also predicts the type of disease those mutations may trigger.

15 Dec 2025

Virus shells use asymmetry to control RNA release and infection

Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new research led by scientists at Penn State reveals a deliberate imbalance in their shape that helps them infect their hosts.

12 Dec 2025

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

A prospective, multicenter cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) has validated an improved method for predicting treatment benefits in patients with hormone receptor-positive (HR+) metastatic breast cancer that has spread primarily or exclusively to the bones.

12 Dec 2025

Researchers identify chromatin accessibility changes driving stem cell transformation in MDS

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation.

12 Dec 2025

Massive genetics study shows what truly separates and unites 14 psychiatric disorders

This large-scale genomic analysis of 14 psychiatric disorders shows that most heritable risk is shared across five broad genetic factors, with only limited disorder-specific variation. The study maps where risks converge or diverge biologically, revealing distinct cell type signatures and developmental pathways that may guide future diagnostic and therapeutic frameworks.

12 Dec 2025

Study reveals shared genetic roots across multiple psychiatric disorders

Distinct psychiatric disorders have more in common biologically than previously believed, according to the largest and most detailed analysis to date of how genes influence mental illness.

11 Dec 2025

Researchers discover the enzyme responsible for chromothripsis in cancer

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.

11 Dec 2025

Shared genetic roots of 14 psychiatric disorders revealed

Researchers from the Psychiatric Genomics Consortium (PGC) report that most genetic influences on mental illness are shared across diagnostic categories, revealing a more interconnected biological landscape than traditional classifications suggest.

11 Dec 2025

AI turns routine pathology slides into powerful maps of the tumor immune landscape

A large study shows that routine H&E pathology slides contain rich spatial proteomic signals that can be decoded by AI to model the tumor immune microenvironment at population scale. By generating virtual multiplex immunofluorescence images, GigaTIME enables pan-cancer discovery of immune patterns linked to invasion stage, survival, and genomic alterations.

10 Dec 2025

Deep learning uncovers why synthetic cannabinoids cause harmful effects

New psychoactive substances, originally developed as potential analgesics but abandoned due to adverse side effects, may still have pharmaceutical value if researchers could nail down the causes of those side effects.

10 Dec 2025

AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer

An artificial intelligence (AI) model created by integrating clinical, molecular, and histopathological data significantly improved recurrence risk stratification in hormone receptor (HR)-positive, HER2-negative breast cancer, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA circulating in the blood.

9 Dec 2025

Genomic News and Research

ACE2 protein may play a protective role against high blood pressure and type 2 diabetes

Social living allows genetic effects to spread through the gut microbiome

AI tool reveals hidden proteins in Earth’s vital microalgae

First-of-its-kind mRNA system switches on therapeutic genes inside targeted cells

Tau biology expands beyond microtubules to neurodegeneration, metabolism and mental illness

SARS-CoV-2 evolves after jumping from humans to zoo animals

Indoor tanning loads normal skin with mutations linked to melanoma

New initiative aims to transform care for early-onset cancer patients

Novel AI tool not only identifies genetic mutations but also predicts the type of disease

Virus shells use asymmetry to control RNA release and infection

Metabolic imaging enables early response prediction in bone-dominant metastatic breast cancer

Researchers identify chromatin accessibility changes driving stem cell transformation in MDS

Massive genetics study shows what truly separates and unites 14 psychiatric disorders

Study reveals shared genetic roots across multiple psychiatric disorders

Researchers discover the enzyme responsible for chromothripsis in cancer

Shared genetic roots of 14 psychiatric disorders revealed

AI turns routine pathology slides into powerful maps of the tumor immune landscape

Deep learning uncovers why synthetic cannabinoids cause harmful effects

AI model improves recurrence risk stratification in HR-positive, HER2-negative breast cancer

Highly sensitive CRISPR-based method designed to detect low-frequency cancer mutations

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News