Induced Pluripotent Stem Cells News and Research

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Scientific Symposium at LABVOLUTION focuses on key issues in life sciences

The Scientific Symposium at LABVOLUTION will be focusing on key issues in the life sciences. Accordingly, a high level of visitor demand is anticipated.

From LABVOLUTION 25 Mar 2019

Antidepressant drugs may not work when neurons are out of shape

elective serotonin reuptake inhibitors are the most commonly prescribed medication for major depressive disorder, yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.

22 Mar 2019

Major success achieved by Axol Bioscience may help design new brain models

Axol Bioscience, a partner in the EU-funded MESO-BRAIN project (GA # 713140) has had a new proposal selected for funding by the EU through the FET (Future Emerging Technologies) Launchpad scheme.

From Axol Bioscience Ltd 21 Mar 2019

MIT announces creation of the Alana Down Syndrome Center

As part of MIT's continued mission to help build a better world, the Institute announced the creation of the Alana Down Syndrome Center, an innovative new research endeavor, technology development initiative, and fellowship program launched with a $28.6 million gift from Alana Foundation, a nonprofit organization started by Ana Lucia Villela of São Paulo, Brazil.

21 Mar 2019

Researchers find potential therapeutic strategy to treat Alzheimer's

Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro) have identified a potential therapeutic strategy to treat Alzheimer's, according to a study published in Journal of Neuroscience.

20 Feb 2019

CRISPR technology creates pluripotent stem cells that are 'invisible' to the immune system

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants.

18 Feb 2019

Increased activity of EHMT2 gene deficient neurons could cause autism in humans

A novel investigation into the impacts of neuronal mutations on autism-related characteristics in humans has been described in the open-access journal eLife.

13 Feb 2019

New process efficiently reprograms stem cells in one step using measles virus vector

Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.

13 Feb 2019

Researchers generate transplantable, functional B-1 cells from mice

Functional B-1 cells derived from mouse embryonic stem cells are capable of long-term engraftment and secrete natural antibodies after transplantation in mice, researchers report February 7 in the journal Stem Cell Reports.

8 Feb 2019

New breakthrough study can impact drug development and personalized medicine

A breakthrough for brain tumor drug development and personalized medicine published today in Nature Scientific Reports.

6 Feb 2019

Researchers identify treatable mechanism in patients with schizophrenia

For reasons that are unclear, schizophrenia patients have fewer connections between the neurons in the brain. Researchers at Karolinska Institutet, Sweden, and Massachusetts General Hospital, USA, have now succeeded in creating human cell models that show that there is an excessive degradation of connections in the brain of these patients, and they have been able to link this to a genetic risk variant for the disease.

4 Feb 2019

Salk researchers pin down why some patients don't respond to common antidepressants

The most commonly prescribed antidepressants, selective serotonin reuptake inhibitors, lift the fog of depression for many people. But for around a third of people with major depressive disorder, SSRIs don't make much of a difference.

1 Feb 2019

Researchers identify why heart attack triggers arrhythmia in some people

A team of researchers led by the University of California San Diego has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm, or arrhythmia, after experiencing a heart attack. They have also identified a drug candidate that can block this pathway.

29 Jan 2019

Research provides new understanding of genome regulation in early life

After the fertilization of an egg cell, two become one; two sets of genetic information combine to form a genome. We can think of the egg and sperm as information capsules with stored instructions for starting a new life, but post fertilization, what kick starts the interpretation of these instructions?

29 Jan 2019

Low doses of anti-HIV drug appear to reduce tau protein in neurons of Alzheimer’s patients

The accumulation of amyloid beta plaques and tangles of a protein called tau in the brain are hallmarks of Alzheimer's disease.

27 Jan 2019

UCLA researchers demonstrate new technique to develop cancer-fighting T cells

A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells -- which can give rise to every cell type in the body and which can be grown indefinitely in the lab -- into becoming mature T cells capable of killing tumor cells.

18 Jan 2019