Interleukin 5 News and Research

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New microneedles could monitor melanoma therapy response

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do.

21 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Researchers used human transcriptomic data to differentiate the molecular mechanisms associated with two phenotypes of allergic rhinitis: rhinitis and rhinitis with asthma.

17 Aug 2023

Study finds inverse correlation between dietary magnesium intake and peripheral arterial disease

Researchers conducted a cross-sectional study to investigate the association between dietary magnesium intake and peripheral arterial disease (PAD).

16 Aug 2023

The gut microbiome of critically ill individuals and its modification by immunonutrition and probiotics

Gut dysbiosis among critically ill individuals

16 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

Novel antibody could be safer and more effective than existing treatments for autoimmune diseases

Researchers have shown that a novel antibody generated to target an 'essential amino acid sequence' of both interleukin-17A and F has greater activity and potentially fewer side effects than existing biological therapies for conditions such as as rheumatoid arthritis (RA), psoriasis, and inflammatory bowel disease (IBD).

14 Aug 2023

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

How complementarity-determining region (CDR) loops in the single-chain variable fragment (scFv) influence chimeric antigen receptor (CAR)-T cell behavior.

14 Aug 2023

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Recently published preclinical data by City of Hope scientists shows the immunotherapy is effective. Advanced ovarian cancer patients are now being enrolled in a Phase 1 first-in-human trial.

10 Aug 2023

How does sun exposure affect skin microbiota composition and diversity?

Researchers recruited healthy volunteers to study how ultraviolet radiation exposure impacted their skin microbiota composition, diversity, and overall skin health.

10 Aug 2023

How conversion between different types of cell death contributes to disease

Researchers elucidate the role of cell death in the pathogenesis of different diseases.

10 Aug 2023

The immune-modulatory effect of lenvatinib investigated in new study

Researchers explore the effect of lenvatinib treatment on patients with advanced thyroid cancer.

9 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

Managing inflammatory bowel disease during pregnancy

Researchers presented information on scientific evidence-based inflammatory bowel disease management methods during pregnancy.

7 Aug 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Research sheds light on the causes of endometriosis-related pelvic pain

Pelvic pain in women with endometriosis is attributed to neuroinflammation. Researchers investigated biochemical mediators of endometriosis-associated pelvic pain to provide a foundation to identify new drugs to improve symptoms and quality of life.

3 Aug 2023

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

A University of Ottawa-led research team has published rigorous new research that advances a quest to understand a puzzling – and heartbreaking – ultra-rare disease that's found almost exclusively in boys.

3 Aug 2023

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

Researchers evaluated the physiological roles of an antimicrobial peptide.

3 Aug 2023

The impact of medicinal plants on the gut microbiome in cancer

Researchers evaluate the associations between medicinal plants, the gut microbiome, and cancer.

2 Aug 2023

Interleukin 5 News and Research

New microneedles could monitor melanoma therapy response

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Interactomics-based analysis suggests that rhinitis and rhinitis with asthma are mechanistically different diseases

Study finds inverse correlation between dietary magnesium intake and peripheral arterial disease

The gut microbiome of critically ill individuals and its modification by immunonutrition and probiotics

Genetic determinants of retinol circulation and their impact on health

Novel antibody could be safer and more effective than existing treatments for autoimmune diseases

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

How does sun exposure affect skin microbiota composition and diversity?

How conversion between different types of cell death contributes to disease

The immune-modulatory effect of lenvatinib investigated in new study

Identification of plasma proteins associated with ovarian cancer risk

Managing inflammatory bowel disease during pregnancy

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Research sheds light on the causes of endometriosis-related pelvic pain

Study sheds light on mechanisms behind a rare disease found almost exclusively in boys

Unlocking the potential of Reg3γ: new insights into its metabolic functions and therapeutic prospects

The impact of medicinal plants on the gut microbiome in cancer

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