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Neurostimulation improves movement in adults with spinal muscle atrophy

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal muscle atrophy (SMA), an inherited neuromuscular disease.

5 Feb 2025

Alzheimer’s disease may leave early signs in the gut, study finds

Scientists used high-resolution 3D X-ray imaging to uncover major structural and immune changes in the gut of Alzheimer's disease models, suggesting a potential early biomarker.

3 Feb 2025

3D-printed brain-like model helps unlock neuron growth secrets

Key cells in the brain, neurons, form networks by exchanging signals, enabling the brain to learn and adapt at incredible speed.

31 Jan 2025

Researchers create high-performance artificial neurons for advanced perception systems

Artificially engineered biological processes, such as perception systems, remain an elusive target for organic electronics experts due to the reliance of human senses on an adaptive network of sensory neurons, which communicate by firing in response to environmental stimuli.

30 Jan 2025

Study reveals how glial cells respond to damage in neuron dendrites

Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste, and protect neurons from harm.

29 Jan 2025

Researchers identify brain circuit to reduce anxiety without side effects

Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.

28 Jan 2025

Decades of DNA expansion linked to Huntington’s disease neurodegeneration

Researchers uncover how slow CAG repeat expansions in neurons drive Huntington’s disease over decades.

24 Jan 2025

Breakthrough discovery sheds light on how brain cells activate learning genes

A breakthrough study published today in the Journal of Neuroscience sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and memory.

21 Jan 2025

Early brain changes in Huntington’s disease detected two decades before symptoms

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease, finds a new study led by UCL researchers.

17 Jan 2025

Scientists discover new mechanism behind Huntington’s disease brain cell death

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

16 Jan 2025

Researchers develop a computational model of grid cell-mediated episodic encoding

Nearly 50 years ago, neuroscientists discovered cells within the brain's hippocampus that store memories of specific locations. These cells also play an important role in storing memories of events, known as episodic memories. While the mechanism of how place cells encode spatial memory has been well-characterized, it has remained a puzzle how they encode episodic memories.

16 Jan 2025

Research identifies role of PV interneurons in pain processing

A research team led by Prof. HU Li at the Institute of Psychology of the Chinese Academy of Sciences, has revealed that parvalbumin (PV) interneurons in the primary somatosensory cortex (S1) preferentially encode pain intensity and drive nociceptive-evoked gamma oscillations (GBOs).

13 Jan 2025