Protein Synthesis News and Research

RSS

Scientists identify hidden signals in RNAs that control protein synthesis

Scientists have long known that RNA encodes instructions to make proteins. The building blocks that comprise RNA - A, U, C, and Gs - form a blueprint for the protein-making machinery in cells. To make proteins, the machinery latches on RNA at one end and then scans along the RNA until it reaches an AUG string, which is the signal to start translating the genetic code into a protein.

17 Jul 2018

New drug strategy can alleviate multiple behavioral, cellular deficiencies in FXS mouse model

Research in mice shows that a pharmacological strategy can alleviate multiple behavioral and cellular deficiencies in a mouse model of fragile X syndrome, the most common inherited form of intellectual disability and a major single-gene cause of autism spectrum disorders.

13 Jul 2018

Researchers develop novel approach to bridge gap in cell-free systems

Engineering cellular biology, minus the actual cell, is a growing area of interest in biotechnology and synthetic biology.

13 Jul 2018

Alternative splicing plays vital role in adult muscle mass maintenance

Despite the importance that changes in muscle mass have in aging, overall body metabolism and in chronic disease, we still don't fully understand the mechanisms that contribute to the maintenance of adult muscle mass.

11 Jul 2018

Cellular 'garbage disposal' may actually work on some of the proteins to neuronal development

Johns Hopkins researchers have found that the cellular "garbage disposal," known to scientists as proteasomes, may not only be responsible for the removal of cellular waste, but actually work on some of the most important proteins to neuronal development.

11 Jul 2018

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption of a fine balance in the composition of ribosomes (huge molecules that translate the genetic code into proteins) results in a shutdown of cancer cell proliferation, triggering a process called senescence.

26 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Jumping genes or transposons and their role in the genetic code

Researchers have found that there a numerous transposons or “jumping genes” within the genetic code that is responsible for development of the embryo and its growth. These were earlier thought to be junk or useless parts of the genome.

22 Jun 2018

Researchers uncover new therapeutic opportunity in the treatment of malignant melanoma

A team of researchers led by Dr Pierre Close, WELBIO researcher at the ULiège GIGA Institute and Dr Francesca Rapino has uncovered a new therapeutic opportunity in the treatment of malignant melanoma that acquired resistance to targeted therapies.

21 Jun 2018

Scientists develop method to determine metabolic activity of neural networks

During the last decade, neurobiologists's attention has been focused on the study of the functioning of neural networks rather than single nerve cells.

14 Jun 2018

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

One of the most frequent causes of drug-resistant epilepsy, considered a difficult disease to control, is a brain malformation known as focal cortical dysplasia.

16 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Researchers uncover mechanism critical to keeping blood stem cells functional

Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function - and defective regulation of protein production is common in certain types of aggressive human blood cancers.

6 Apr 2018

New $3.2 million grant funds research to advance promising malaria vaccine

The Global Health Innovative Technology Fund has awarded the University of Florida and partners in the United States and Japan $3.2 million to advance a promising vaccine to prevent transmission of malaria.

29 Mar 2018

TSRI scientists discover new pathway to promote mitochondrial function during stress

Scientists at The Scripps Research Institute have discovered a new pathway in cells that promotes mitochondrial function during times of stress, a response that can guard against disease as we age.

15 Mar 2018

TSRI researchers show path to developing treatments for Charcot-Marie-Tooth disease

Scientists at The Scripps Research Institute have now shown a path to developing treatments for disease subtype CMT2D.

8 Mar 2018

Researchers determine cause of difficult-to-control mitochondrial diseases

A Japanese research group has discovered that taurine is conjugated with mitochondrial transfer RNAs (tRNAs), small RNAs that decode genetic information, and that taurine deficiency in tRNA dramatically reduces both mitochondrial protein translation and impairs mitochondrial membrane integrity.

7 Mar 2018

Daffodils may hold secrets of cancer cure

A natural extract from daffodils may help in treatment of cancer find researchers at the Faculty of Sciences at the ULB led by Denis Lafontaine. The team published their research titled, “The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth” in the journal Structure that appeared in their latest issue this week.

1 Mar 2018

Fresh insights into depression could pave way for new therapies

Fresh insights into changes in the brain linked to depression could pave the way for new therapies.

27 Feb 2018

Research reveals anti-cancer effects of natural extract from Daffodils

A research describes the anti-cancer effects of a natural alkaloid extracted from Daffodils. Led by Denis Lafontaine, affiliated with the Faculty of Sciences at the ULB, the researchers have discovered that this compound triggers the activation of an anti-tumoral surveillance pathway.

26 Feb 2018