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Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

In a study published in the journal Genes & Diseases, researchers from Army Medical University and Shenzhen University investigated the pivotal role of miR-18a-5p, a microRNA, in the development and progression of osteoblastic lesions resulting from prostate cancer (PCa) bone metastasis.

9 Oct 2023

EMC1 protein found to play pivotal role in retinal vascular development

In a groundbreaking study published in the journal Genes & Diseases, researchers from University of Electronic Science and Technology of China have uncovered a key relationship between the EMC1 protein and retinal vascular development.

9 Oct 2023

Study sheds light on PRMT1's role in gastric cancer progression

In a study published in the journal Genes & Diseases, researchers from Southwest University, and Southwest Medical University investigated PRMT1, a protein previously known to be overexpressed in gastric cancer cells.

9 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

The connection between the CHD gene and autism-related gastrointestinal (GI) manifestations.

4 Oct 2023

Could plant-based phytonutrients be the secret weapon against obesity?

This comprehensive review in the journal Foods explores the therapeutic potential of phytonutrients in combating obesity. The paper delves into various plant-based compounds like polyphenols, alkaloids, and terpenoids, detailing their mechanisms of action in inhibiting fat accumulation, regulating metabolism, and even altering gut microbiota.

1 Oct 2023

Study reveals new insights into how the immune system prevents autoimmunity

Researchers at Stanford University School of Medicine, Yale University School of Medicine, and the Hospital for Special Surgery Research Institute have uncovered new details about how the immune system prevents the production of antibodies that can recognize and damage the body's own, healthy tissues.

29 Sep 2023

Racial disparities in survival rates among patients with multiple myeloma and diabetes

Patients with multiple myeloma, a blood cancer of plasma cells in the bone marrow, who also have diabetes have a reduced overall survival when compared to those without diabetes.

29 Sep 2023

Study reveals how DNA damage caused by chromosomal instability increases cancer invasiveness

Chromosomal instability is a phenomenon characterized by rapid changes in the number and structure of chromosomes during cell division.

28 Sep 2023

Blocking Notch signaling pathway could reverse age-related bone loss

A cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.

27 Sep 2023

Study identifies four novel receptors potentially linking endometrial cancer with PCOS

A new research paper was published in Oncotarget's Volume 14 on September 22, 2023, entitled, "Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas."

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

AlphaMissense, an adaptation of AlphaFold, offers a highly accurate model for predicting the pathogenicity of human proteome-wide missense variants at the single amino acid level. The model outperforms existing methods, providing valuable insights for diagnosing rare diseases and developing targeted therapies.

20 Sep 2023

Signaling Pathway News and Research

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

EMC1 protein found to play pivotal role in retinal vascular development

Study sheds light on PRMT1's role in gastric cancer progression

Effectiveness of Lactobacillus in treating inflammatory bowel disease

Study reveals link between CHD8 gene, gut abnormalities, and autism-related behaviors

Could plant-based phytonutrients be the secret weapon against obesity?

Study reveals new insights into how the immune system prevents autoimmunity

Racial disparities in survival rates among patients with multiple myeloma and diabetes

Study reveals how DNA damage caused by chromosomal instability increases cancer invasiveness

Blocking Notch signaling pathway could reverse age-related bone loss

Study identifies four novel receptors potentially linking endometrial cancer with PCOS

Could CaMKK2 enzyme be the key to treating bipolar disorder?

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

HNP-1 may be a promising therapeutic agent for hypertensive left ventricular hypertrophy

Study sheds new light on the role of 'TonEBP' protein in lupus and lupus nephritis

Genetics and diet shape insulin signaling in mice

A combination of inhibitors may suppress tumor growth and prevent cancer relapse

Arf1 inhibition induces tumor regression by promoting T cell infiltration

Human post-implantation embryo models show promise in unraveling early development

PI3K pathway rewiring drives prostate cancer growth

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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