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Researchers use pioneering stem cell techniques to better understand causes of Spinal Muscular Atrophy

New research from the Advanced Gene and Cell Therapy Lab at Royal Holloway, University of London has used pioneering stem cell techniques to better understand why certain cells are more at risk of degenerating in Spinal Muscular Atrophy than others.

1 Jul 2015

Nuclea and Aelan partner to develop, commercialize novel biomarker tests using STEM cells as models

Nuclea Biotechnologies Inc. announced today that it is partnering with Aelan Cell Technologies Inc. (San Francisco, California) for the development, validation and commercialization of novel biomarker tests and companion diagnostics using human STEM cells as models.

1 Jul 2015

Bibby Scientific’s Integrity 10 Reaction Station helps scientists to speed up drug development research

Analytical scientists at the University of Lincoln’s School of Pharmacy are accelerating their drug development research thanks to Bibby Scientific’s Integrity 10 Reaction Station, which enables different reactions to be performed simultaneously with varied process conditions.

1 Jul 2015

UCSD researchers discover cell signaling pathway that controls initiation, progression of colorectal cancer

Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be predictive of cancer survival rates.

1 Jul 2015

Omega-3 fatty acids and antioxidants may benefit people with Alzheimer's disease

Here's more evidence that fish oil supplementation and antioxidants might be beneficial for at least some people facing Alzheimer's disease: A new report published in the July 2015 issue of The FASEB Journal describes the findings of a very small study in which people with mild clinical impairment, such as those in the very early stages of the disease, saw clearance of the hallmark amyloid-beta protein and reduced inflammation in neurological tissues.

1 Jul 2015

Tree nut consumption associated with lower body weight and lower risk of obesity

In a study published this week in Nutrition Journal*, researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index (p=0.004), systolic blood pressure (p=0.001), insulin resistance (p=0.043) and higher levels of high-density lipoprotein-cholesterol (good cholesterol) (p=0.022).

30 Jun 2015

Researchers map physical properties of live breast cancer cells using advanced AFM technology

Researchers who developed a high-speed form of atomic force microscopy have shown how to image the physical properties of live breast cancer cells, for the first time revealing details about how deactivation of a key protein may lead to metastasis.

30 Jun 2015

Researchers explore why some mutations can cause severe disease in humans, but benign in animals

Researchers at Duke University School of Medicine and Brigham and Women's Hospital, Harvard Medical School have identified a mechanism that explains why some mutations can be disease-causing in one genome but benign in another.

30 Jun 2015

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Scientists have discovered a new inherited form of obesity and type 2 diabetes in humans. A large number of genes are involved in regulating body weight, and there are now over 30 genes known in which people with harmful changes in DNA sequence become extremely overweight. Similarly, there are a number of genes that can, when altered, cause type 2 diabetes. These conditions are inherited through families in exactly the same way as disorders such as cystic fibrosis or Huntington's disease.

30 Jun 2015

Researchers complete participants’ enrollment in Phase III trial of vaginal ring for HIV prevention

In a first for HIV prevention, an international team of researchers have completed follow-up of participants enrolled in a pivotal Phase III trial that tested the safety and effectiveness of a vaginal ring for preventing HIV in women.

30 Jun 2015

New informatics technology could accelerate search for potential new drug targets on protein structures

Researchers have developed a new informatics technology that analyzes existing data repositories of protein modifications and 3D protein structures to help scientists identify and target research on "hotspots" most likely to be important for biological function.

30 Jun 2015

New discovery could lead to personalized treatment for colon cancer

A UNC Lineberger Comprehensive Cancer Center discovery of just how a certain tumor suppressor molecule works to prevent tumor growth could lead to a personalized treatment approach for colon cancer.

30 Jun 2015

Study may predict which glioblastoma patients may respond well to dasatinib drug treatment

Clinicians testing the drug dasatinib, approved for several blood cancers, had hoped it would slow the aggressive growth of the deadly brain cancer glioblastoma; however, clinical trials to date have not found any benefit. Researchers at Mayo Clinic, who conducted one of those clinical trials, believe they know why dasatinib failed — and what to do about it.

30 Jun 2015

Researchers identify better way to screen for lung cancer

The Valley Hospital in Ridgewood, NJ, is pleased to announce that two of its oncologists and a research scientist are helping pave the way to an easier, more accurate, less invasive way to screen for the most common form of lung cancer. Lung cancer is the most common cancer in men worldwide and the number one cancer killer in the United States.

30 Jun 2015

Study could point the way to new treatments for people with severe asthma

The immune response that occurs in patients with severe asthma is markedly different than what occurs in milder forms of the lung condition, according to researchers from the University of Pittsburgh School of Medicine. Those unique features could point the way to new treatments, they said in an article published online today in the Journal of Clinical Investigation.

30 Jun 2015

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

Canada's first human gene therapy trial for eyes -- the replacement of a faulty gene with a healthy one -- is now underway at the Royal Alexandra Hospital to preserve and potentially restore vision for people with a genetic disorder that leaves them blind by middle age.

30 Jun 2015

University of Oklahoma professor finds key mosquito protein for development of new malaria vaccine

A University of Oklahoma professor studying malaria mosquito interaction has discovered a new mosquito protein for the development of a new vaccine that is expected to stop the spread of the disease in areas where it is considered endemic.

30 Jun 2015

Study on fruit flies, brewer's yeast may provide clues about cause of Spinal Muscular Atrophy

Scientists at the University of Malta and the Institut de Génétique Moléculaire de Montpellier (CNRS/Université de Montpellier) have shown that fruit flies and brewer's yeast can reveal clues about the cause of Spinal Muscular Atrophy (SMA), the most common genetic killer of infants.

30 Jun 2015

Drinking low-calorie cranberry juice may help lower risk of heart disease, diabetes and stroke

A new study reveals that drinking low-calorie cranberry juice cocktail may help lower the risk of chronic diseases that rank among the leading causes of death worldwide, including heart disease, diabetes and stroke. The finding is welcome news considering the World Health Organization estimates the trio of diseases annually claim 15.6 million lives around the globe.

30 Jun 2015

Kay E. Davies named recipient of ASHG's 2015 William Allan Award

The American Society of Human Genetics has named Kay E. Davies, DPhil, Dr. Lee's professor of anatomy, associate head of the medical sciences division; and director of the Medical Research Council Functional Genomics Unit in the department of physiology, anatomy and genetics at the University of Oxford, the 2015 recipient of the annual William Allan Award.

30 Jun 2015

G Protein News and Research

Researchers use pioneering stem cell techniques to better understand causes of Spinal Muscular Atrophy

Nuclea and Aelan partner to develop, commercialize novel biomarker tests using STEM cells as models

Bibby Scientific’s Integrity 10 Reaction Station helps scientists to speed up drug development research

UCSD researchers discover cell signaling pathway that controls initiation, progression of colorectal cancer

Omega-3 fatty acids and antioxidants may benefit people with Alzheimer's disease

Tree nut consumption associated with lower body weight and lower risk of obesity

Researchers map physical properties of live breast cancer cells using advanced AFM technology

Researchers explore why some mutations can cause severe disease in humans, but benign in animals

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Researchers complete participants’ enrollment in Phase III trial of vaginal ring for HIV prevention

New informatics technology could accelerate search for potential new drug targets on protein structures

New discovery could lead to personalized treatment for colon cancer

Study may predict which glioblastoma patients may respond well to dasatinib drug treatment

Researchers identify better way to screen for lung cancer

Study could point the way to new treatments for people with severe asthma

Canada's first human gene therapy trial for choroideremia now underway at Royal Alexandra Hospital

University of Oklahoma professor finds key mosquito protein for development of new malaria vaccine

Study on fruit flies, brewer's yeast may provide clues about cause of Spinal Muscular Atrophy

Drinking low-calorie cranberry juice may help lower risk of heart disease, diabetes and stroke

Kay E. Davies named recipient of ASHG's 2015 William Allan Award

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