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A core system for the implementation of task sets

Scientists have used data from scans of 183 subjects to identify brain areas that consistently become active in a variety of cognitive tasks, such as reading, learning a rhythm or analyzing a picture.

7 Jun 2006

Midbrain, striatal and amygdalar dopaminergic dysfunction in ADHD

The brain's dopamine system, which has long been associated with reward learning and reward-related behavior, works differently in treated and untreated attention deficit hyperactivity disorder (ADHD) individuals.

7 Jun 2006

TB drug may cure Parkinson-type symptoms of manganese intoxication

Researchers have discovered that a drug used to treat tuberculosis apparently cures patients of a Parkinson's-like illness suffered by thousands of mineworkers, welders and others exposed to high levels of the metal manganese.

7 Jun 2006

Activity in the lateral prefrontal cortex reflects multiple steps of future events in action plans

Studies in which monkeys were asked to manipulate computer cursors for fruit juice rewards have revealed that the brain's "executive" center plans behaviors not by specifying movements required for given actions, but rather the events that will result from those actions.

6 Jun 2006

Novel research points to promising relief target for chronic pain

By some accounts, chronic pain affects nearly 100 million Americans from such varied causes as arthritis, sciatica, cancer, diabetes. Most forms of pain result from identifiable causes which serve the "good" purpose in warning of a real physical problem that needs attention, or rest.

6 Jun 2006

Researchers show that different forms of amyloid beta lead to neural damage in different ways

Researchers at UC Irvine have shown that different forms of amyloid beta lead to neural damage in different ways, leading to an increasingly complex view of amyloid toxicity in the Alzheimer brain.

6 Jun 2006

Naturally produced protein that helps protect us from cancer may also determine how long we live

The reason why people are at greater risk of developing cancer as they get older may be explained by research published today.

From The University of Manchester 1 Jun 2006

Molecular pathway may contribute to age related diseases

A common molecular denominator in aging and many age-related diseases is oxidative stress.

1 Jun 2006

Siestas may help treat obesity and eating disorders

The Spaniards may have been right all along - a siesta after a hearty lunch is natural, new research suggests.

From The University of Manchester 1 Jun 2006

Cause of neurodegeneration in Huntington's disease discovered

The severe neurodegeneration associated with Huntington's disease may result from molecular mutations that block the transport of nutrients within cells.

1 Jun 2006

Identification of molecule that links both sides of the brain

A Queensland Brain Institute-led team has identified a molecule that plays a key role in establishing the major nerve connections between each side of the adult brain.

24 May 2006

Researchers identify target of the widely prescribed antidepressant Prozac

Researchers at Cold Spring Harbor Laboratory on Long Island have identified which among several different kinds of cells in the brain is the chief target of the widely prescribed antidepressant Prozac.

23 May 2006

Brain research offers insight into mechanisms of prejudice

By scanning subjects' brains while they were thinking about people either politically like or different from them, researchers have found that different areas of the brain are active in the two cases.

17 May 2006

Search for gene search for sporadic amyotrophic lateral sclerosis

Though it's the more common form of the disease, sporadic Amyotrophic Lateral Sclerosis (ALS), which affects roughly 90 percent of those living with the fatal neurodegenerative illness, has been the one less studied, simply because, unlike familial ALS, no genes have turned up.

17 May 2006

Taking astrocytes seriously

By blowing gentle puffs of air onto a mouse's whiskers and watching how its brain reacts, scientists are discovering that a long-overlooked signaling system in the brain is crucial to our everyday activity.

17 May 2006

German scientists synthesize new compound that reduces stroke damage

A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.

16 May 2006

SOX2 neural stem cell gene important in eye development

Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place.

16 May 2006

Researchers link novel mutated gene to mental retardation and imbalance syndrome

Researchers at the University of California, San Diego School of Medicine have identified a genetic cause for a form of pediatric brain malformation involving the cerebellum.

11 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Autopsy study of mild cognitive impairment

A study led by Mayo Clinic demonstrates that mild cognitive impairment, a memory disorder considered a strong early predictor of Alzheimer's disease, not only results in behavioral symptoms, but also structural changes that can be identified in the brain. Findings will be published in the May issue of Archives of Neurology.

9 May 2006